Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Yunkou Wu"'
Autor:
Jennifer M. Coughlin, Yong Du, Wojciech G. Lesniak, Courtney K. Harrington, Mary Katherine Brosnan, Riley O’Toole, Adeline Zandi, Shannon Eileen Sweeney, Rehab Abdallah, Yunkou Wu, Daniel P. Holt, Andrew W. Hall, Robert F. Dannals, Lilja Solnes, Andrew G. Horti, Martin G. Pomper
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Purpose Study of the contribution of microglia to onset and course of several neuropsychiatric conditions is challenged by the fact that these resident immune cells often take on different phenotypes and functions outside the living brain. I
Externí odkaz:
https://doaj.org/article/76ad44458537447c9f4f54f7ef2310a0
Autor:
Catherine A. Foss, Alvaro A. Ordonez, Ravi Naik, Deepankar Das, Andrew Hall, Yunkou Wu, Robert F. Dannals, Sanjay K. Jain, Martin G. Pomper, Andrew G. Horti
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:4088-4096
Macrophages represent an essential means of sequestration and immune evasion for Mycobacterium tuberculosis. Pulmonary tuberculosis (TB) is characterized by dense collections of tissue-specific and recruited macrophages, both of which abundantly expr
Autor:
Yong Du, Jennifer M. Coughlin, Mary Katherine Brosnan, Allen Chen, Laura K. Shinehouse, Rehab Abdallah, Martin A. Lodge, William B. Mathews, Chen Liu, Yunkou Wu, Il Minn, Paige Finley, Andrew W. Hall, Wojciech G. Lesniak, Robert F. Dannals, Andrew G. Horti, Martin G. Pomper
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging.
Autor:
Shaowei Bo, Julia Stabinska, Yunkou Wu, Kowsalya Devi Pavuluri, Aruna Singh, Zinia Mohanta, Rehan Choudhry, Max Kates, Farzad Sedaghat, Zaver Bhujwalla, Martin G. Pomper, Michael T. McMahon
Publikováno v:
NMR in Biomedicine. 36
Here we describe and assess the potential of 14 newly synthesized imidazole-4,5-dicarboxyamides (I45DCs) for pH and perfusion imaging. A number of these aromatic compounds possess large labile proton chemical shifts (up to 7.7 ppm from water) due to
Autor:
Mathews, William B.1 bmathews@jhu.edu, Yunkou Wu1, Horti, Andrew G.1, Naik, Ravi1, Hall, Andrew W.1, Holt, Daniel P.1, Dannals, Robert F.1
Publikováno v:
Journal of Labelled Compounds & Radiopharmaceuticals. Nov2019, Vol. 62 Issue 13, p903-908. 6p.
Autor:
Yong Du, Jennifer M. Coughlin, Mary Katherine Brosnan, Allen Chen, Laura K. Shinehouse, Rehab Abdallah, Martin A. Lodge, William B. Mathews, Chen Liu, Yunkou Wu, Andrew Hall, Wojciech Lesniak, Robert Dannals, Andrew Horti, Martin Pomper
Purpose: We report findings from the first-in-human study of [ 11 C]MDTC, a radiotracer developed to image the cannabinoid receptor type 2 (CB2R) with positron emission tomography (PET). Methods: Ten healthy adults were imaged according to a 90 min d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::621ad5840c34a6250cd0d1343675e3e5
https://doi.org/10.21203/rs.3.rs-1479303/v1
https://doi.org/10.21203/rs.3.rs-1479303/v1
Autor:
William B. Mathews, Yunkou Wu, Daniel P. Holt, Ravi Naik, Andrew Hall, Andrew G. Horti, Robert F. Dannals
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:903-908
In this practitioner protocol, the radiochemical synthesis of [11 C]CPPC is described in detail, and a quality control summary of three validation productions is presented. The results indicate that the radiotracer product can be produced in good rad
Autor:
Céline Taglang, Thomas R. Hayes, Renuka Sriram, Robert R. Flavell, Andrew S. Hong, Sinan Wang, Zhen J. Wang, Robert Bok, David M. Wilson, Henry Li, Yunkou Wu, David E. Korenchan, Paola M. Perez, John Kurhanewicz
Publikováno v:
Chemistry – A European Journal. 25:11842-11846
Alterations in Zn2+ concentration are seen in normal tissues and in disease states, and for this reason imaging of Zn2+ is an area of active investigation. Herein, enriched [1-13 C]cysteine and [1-13 C2 ]iminodiacetic acid were developed as Zn2+ -spe
Autor:
Mikhail V. Pletnikov, Heather Valentine, Hwanhee Nam, Olga Pletnikova, Il Minn, Ravi Naik, William B. Mathews, Yunkou Wu, Yong Du, Varia Misheneva, Yuchuan Wang, Matthew D. Smith, Peter A. Calabresi, Wojciech G. Lesniak, Andrew Hall, Juan C. Troncoso, Robert F. Dannals, Alena Savonenko, Catherine LaCourse, Martin G. Pomper, Catherine A. Foss, Andrew G. Horti, Hye Hyun Ahn
Publikováno v:
Proceedings of the National Academy of Sciences. 116:1686-1691
While neuroinflammation is an evolving concept and the cells involved and their functions are being defined, microglia are understood to be a key cellular mediator of brain injury and repair. The ability to measure microglial activity specifically an
Lanthanide-Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Publikováno v:
Angewandte Chemie International Edition. 56:16626-16630
The CEST and T1 /T2 relaxation properties of a series of Eu3+ and Dy3+ DOTA-tetraamide complexes with four appended primary amine groups are measured as a function of pH. The CEST signals in the Eu3+ complexes show a strong CEST signal after the pH w