Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Yunkai ZHU"'
Autor:
Yueming Yuan, An Fang, Zongmei Wang, Zhihui Wang, Baokun Sui, Yunkai Zhu, Yuan Zhang, Caiqian Wang, Rong Zhang, Ming Zhou, Huanchun Chen, Zhen F. Fu, Ling Zhao
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102769- (2023)
Cholesterol-24-hydroxylase (CH24H or Cyp46a1) is a reticulum-associated membrane protein that plays an irreplaceable role in cholesterol metabolism in the brain and has been well-studied in several neuro-associated diseases in recent years. In the pr
Externí odkaz:
https://doaj.org/article/f757cf7b193c460abbb4a5f2d6d1ad88
Autor:
Xiaoyang Zhou, Weiyang Sun, Yu Zhang, Hongjing Gu, Ruixuan Wang, Peng Xie, Yunkai Zhu, Minyue Qiu, Xiaoyan Ding, Hui Wang, Yuwei Gao, Jintao Li
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is responsible for the coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) receptor to enter the host, and the gastrointest
Externí odkaz:
https://doaj.org/article/e75549d82df04fa5ba65147341bf0ec1
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Orthotopic LNCaP xenograft mouse models closely mimic the progression of androgen-dependent prostate cancer in humans; however, orthotopic injection of LNCaP cells into the mouse prostate remains a challenge. Methods Under the gui
Externí odkaz:
https://doaj.org/article/cc8d22f5f4344a4a8031161319df5507
Autor:
Changbai Huang, Fei Feng, Yongxia Shi, Wenhui Li, Ziqiao Wang, Yunkai Zhu, Shuai Yuan, Dandan Hu, Jun Dai, Qiqi Jiang, Rong Zhang, Chao Liu, Ping Zhang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Infection by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has posed a severe threat to global public health. The current study revealed that several inhibitors of protein kinases C (PKCs) possess protective activity a
Externí odkaz:
https://doaj.org/article/d6e60e085b9a40c7914eca1a6f8728d5
Autor:
Ming Zhao, Yu Yu, Li-Ming Sun, Jia-Qing Xing, Tingting Li, Yunkai Zhu, Miao Wang, Yin Yu, Wen Xue, Tian Xia, Hong Cai, Qiu-Ying Han, Xiaoyao Yin, Wei-Hua Li, Ai-Ling Li, Jiuwei Cui, Zhenghong Yuan, Rong Zhang, Tao Zhou, Xue-Min Zhang, Tao Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Coronavirus nucleocapsid (N) protein is important for viral genome packaging and virion assembly. Here the authors show that natural chemical (-)-gallocatechin gallate (GCG) disrupts the liquid–liquid phase separation of N and inhibits SARS-CoV-2 r
Externí odkaz:
https://doaj.org/article/b7901ebbdbb44f8fa47ee44897662e08
Autor:
Yunkai Zhu, Fei Feng, Gaowei Hu, Yuyan Wang, Yin Yu, Yuanfei Zhu, Wei Xu, Xia Cai, Zhiping Sun, Wendong Han, Rong Ye, Di Qu, Qiang Ding, Xinxin Huang, Hongjun Chen, Youhua Xie, Qiliang Cai, Zhenghong Yuan, Rong Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The SARS-CoV-2 spike protein contains a multi-basic cleavage site. Here, the authors show how this multi-basic cleavage site affects entry of SARS-CoV-2 into cells and transmission in the hamster model and identify host factors affecting entry of SAR
Externí odkaz:
https://doaj.org/article/614198775ef44e57a0a5f7bb249a104c
Autor:
Yafei Qu, Xin Wang, Yunkai Zhu, Weili Wang, Yuyan Wang, Gaowei Hu, Chengrong Liu, Jingjiao Li, Shanhui Ren, Maggie Z. X. Xiao, Zhenshan Liu, Chunxia Wang, Joyce Fu, Yucai Zhang, Ping Li, Rong Zhang, Qiming Liang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative agent for the coronavirus disease 2019 (COVID-19) pandemic and there is an urgent need to understand the cellular response to SARS-CoV-2 infection. Beclin 1 is an essential
Externí odkaz:
https://doaj.org/article/66a7b7b7a84145c8ae35f20135b3875d
Autor:
Wenlin Ren, Yunkai Zhu, Yuyan Wang, Hongyang Shi, Yin Yu, Gaowei Hu, Fei Feng, Xiaomin Zhao, Jun Lan, Jianping Wu, Devin J Kenney, Florian Douam, Yimin Tong, Jin Zhong, Youhua Xie, Xinquan Wang, Zhenghong Yuan, Dongming Zhou, Rong Zhang, Qiang Ding
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009392 (2021)
Coronavirus interaction with its viral receptor is a primary genetic determinant of host range and tissue tropism. SARS-CoV-2 utilizes ACE2 as the receptor to enter host cell in a species-specific manner. We and others have previously shown that ACE2
Externí odkaz:
https://doaj.org/article/927b723ecf2d4d9bb7a0e45c96e492ab
Autor:
Xiaohui Ju, Yunkai Zhu, Yuyan Wang, Jingrui Li, Jiaxing Zhang, Mingli Gong, Wenlin Ren, Sai Li, Jin Zhong, Linqi Zhang, Qiangfeng Cliff Zhang, Rong Zhang, Qiang Ding
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009439 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the global pandemic of COVID-19. SARS-CoV-2 is classified as a biosafety level-3 (BSL-3) agent, impeding the basic research into its biology and the development of effective antivira
Externí odkaz:
https://doaj.org/article/df280045ebf4425eac4ddda8b2cee92f
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/08a12d957ceb46b98d0ed7f69dcf9a03