Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yunjung Jin"'
Autor:
Kai Chen, Yuka A. Martens, Axel Meneses, Daniel H. Ryu, Wenyan Lu, Ana Caroline Raulin, Fuyao Li, Jing Zhao, Yixing Chen, Yunjung Jin, Cynthia Linares, Marshall Goodwin, Yonghe Li, Chia-Chen Liu, Takahisa Kanekiyo, David M. Holtzman, Todd E. Golde, Guojun Bu, Na Zhao
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background The aggregation and spread of α-synuclein (α-Syn) protein and related neuronal toxicity are the key pathological features of Parkinson’s disease (PD) and Lewy body dementia (LBD). Studies have shown that pathological species o
Externí odkaz:
https://doaj.org/article/6cbd01c19d96474d84a60117d4afbc0d
Autor:
Yunjung Jin1, Fuyao Li1, Zonghua Li1, Ikezu, Tadafumi C.2, O'Leary, Justin1, Selvaraj, Manikandan1, Yiyang Zhu1, Martens, Yuka A.1, Shunsuke Koga1,3, Santhakumar, Hannah1, Yonghe Li1, Wenyan Lu1, Yang You1, Lolo, Kiara1, DeTure, Michael1, Beasley, Alexandra I.1, Davis, Mary D.1, McLean, Pamela J.1, Ross, Owen A.1, Takahisa Kanekiyo1
Publikováno v:
Science Advances. 9/13/2024, Vol. 10 Issue 37, p1-20. 20p.
Autor:
Yunjung Jin, Fuyao Li, Berkiye Sonoustoun, Naveen Chandra Kondru, Yuka A. Martens, Wenhui Qiao, Michael G. Heckman, Tadafumi C. Ikezu, Zonghua Li, Jeremy D. Burgess, Danilyn Amerna, Justin O’Leary, Michael A. DeTure, Jing Zhao, Pamela J. McLean, Dennis W. Dickson, Owen A. Ross, Guojun Bu, Na Zhao
Publikováno v:
Acta Neuropathologica. 143:641-662
Approximately half of Alzheimer’s disease (AD) brains have concomitant Lewy pathology at autopsy, suggesting that α-synuclein (α-SYN) aggregation is a regulated event in the pathogenesis of AD. Genome-wide association studies revealed that the ε
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe046db23f2c71b438ae91254c8dc0a3
https://doi.org/10.1007/s00401-022-02421-8
https://doi.org/10.1007/s00401-022-02421-8
Autor:
Na Zhao, Wenhui Qiao, Fuyao Li, Yingxue Ren, Jiaying Zheng, Yuka A. Martens, Xusheng Wang, Ling Li, Chia-Chen Liu, Kai Chen, Yiyang Zhu, Tadafumi C. Ikezu, Zonghua Li, Axel D. Meneses, Yunjung Jin, Joshua A. Knight, Yixing Chen, Ligia Bastea, Cynthia Linares, Berkiye Sonustun, Lucy Job, Madeleine L. Smith, Manling Xie, Yong U. Liu, Anthony D. Umpierre, Koichiro Haruwaka, Zachary S. Quicksall, Peter Storz, Yan W. Asmann, Long-Jun Wu, Guojun Bu
Publikováno v:
Journal of Experimental Medicine. 219
TREM2 is exclusively expressed by microglia in the brain and is strongly linked to the risk for Alzheimer’s disease (AD). As microglial responses modulated by TREM2 are central to AD pathogenesis, enhancing TREM2 signaling has been explored as an A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff47cd46285efea4757fe778fe1d7ac
https://doi.org/10.1084/jem.20212479
https://doi.org/10.1084/jem.20212479
Autor:
Yunjung, Jin, Fuyao, Li, Berkiye, Sonoustoun, Naveen Chandra, Kondru, Yuka A, Martens, Wenhui, Qiao, Michael G, Heckman, Tadafumi C, Ikezu, Zonghua, Li, Jeremy D, Burgess, Danilyn, Amerna, Justin, O'Leary, Michael A, DeTure, Jing, Zhao, Pamela J, McLean, Dennis W, Dickson, Owen A, Ross, Guojun, Bu, Na, Zhao
Publikováno v:
Acta neuropathologica. 143(6)
Approximately half of Alzheimer's disease (AD) brains have concomitant Lewy pathology at autopsy, suggesting that α-synuclein (α-SYN) aggregation is a regulated event in the pathogenesis of AD. Genome-wide association studies revealed that the ε4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30856c316aaa01643431664cb386d7eb
https://pubmed.ncbi.nlm.nih.gov/35471463
https://pubmed.ncbi.nlm.nih.gov/35471463
Publikováno v:
Free Radical Biology and Medicine. 141:362-371
Mouse selenoprotein W (SELENOW) is a small protein containing a selenocysteine (Sec, U) and four cysteine (Cys, C) residues. The Sec residue in SELENOW is located within the conserved CXXU motif corresponding to the CXXC redox motif of thioredoxin (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ae8b69e01a36d85201a74ab11f98ee
https://doi.org/10.1016/j.freeradbiomed.2019.07.007
https://doi.org/10.1016/j.freeradbiomed.2019.07.007
Autor:
Hyunwoo Kang, Yunjung Jin, Ick Young Kim, Kwan Young Ko, Jun Ki Jang, Youn Wook Chung, Minju Ham, Chan-Gi Pack, Jea Hwang Lee, Min Kyo Jung, Hisaaki Mihara
Publikováno v:
Cellular and molecular life sciences : CMLS. 77(12)
Selenoprotein P (SELENOP), secreted from the liver, functions as a selenium (Se) supplier to other tissues. In the brain, Se homeostasis is critical for physiological function. Previous studies have reported that SELENOP co-localizes with the apolipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d71a45ace6e41cbcd5412f1170e97b
https://pubmed.ncbi.nlm.nih.gov/31471680
https://pubmed.ncbi.nlm.nih.gov/31471680
Autor:
Jea Hwang Lee, Hyunwoo Kang, Kwan Young Ko, Yunjung Jin, Jun Ki Jang, Minju Ham, Ick Young Kim
Publikováno v:
Cell Death Differ
Adipocyte differentiation is known to be related with endoplasmic reticulum (ER) stress. We have reported that selenoprotein S (SelS) and selenoprotein K (SelK) have a function in the regulation of ER stress and ER-associated degradation. However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a36951669a6ee47882fa30fd442a4ef
https://pubmed.ncbi.nlm.nih.gov/30082770
https://pubmed.ncbi.nlm.nih.gov/30082770
Autor:
Juneyoung Jung, Ick Young Kim, Jiyea Kim, Hyun Kyu Song, Seongman Kang, Byeong Won Kim, Jun Hoe Kim, Yunjung Jin, Joungmok Kim, Heesun Cheong
The initiation of macroautophagy/autophagy is tightly regulated by the upstream ULK1 kinase complex, which affects many downstream factors including the PtdIns3K complex. The phosphorylation of the right position at the right time on downstream molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e954e057c582a2a10e008a59bc0475a
