Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yunjuan, Nie"'
Autor:
Manjula Karpurapu, Yunjuan Nie, Sangwoon Chung, Jiasheng Yan, Patrick Dougherty, Sonal Pannu, Jon Wisler, Ryan Harkless, Narasimham Parinandi, Evgeny Berdyshev, Dehua Pei, John W. Christman
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Extracellular vesicles mediate intercellular communication by transporting biologically active macromolecules. Our prior studies have demonstrated that the nuclear factor of activated T cell cytoplasmic member 3 (NFATc3) is activated in mouse pulmona
Externí odkaz:
https://doaj.org/article/e4c82b57f47e4bf2a0bcb4bf10e5e08e
Autor:
Manjula Karpurapu, Kavita Kumari Kakarala, Sangwoon Chung, Yunjuan Nie, Amritendu Koley, Patrick Dougherty, John W Christman
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301904 (2024)
Our previous research demonstrated that PU.1 regulates expression of the genes involved in inflammation in macrophages. Selective knockdown of PU.1 in macrophages ameliorated LPS-induced acute lung injury (ALI) in bone marrow chimera mice. Inhibitors
Externí odkaz:
https://doaj.org/article/80cab4e703204059aed37f81a8620f5c
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2022 (2023)
Idiopathic pulmonary fibrosis (IPF) is a progressive fatal lung disease with a limited therapeutic strategy. Mitochondrial oxidative stress in macrophages is directly linked to IPF. Elamipretide(SS-31) is a mitochondrion-targeted peptide that has bee
Externí odkaz:
https://doaj.org/article/99b4bdc934394c7d9d41c0c6d270ef45
Autor:
Yunjuan Nie1, Xiaorun Zhai1, Jiao Li1, Aijuan Sun2, Huilian Che1, Christman, John W.3, Gaoshang Chai1, Peng Zhao1 zhaopeng336@jiangnan.edu.cn, Manjula Karpurapu3 manjula.karpurapu@osumc.edu
Publikováno v:
Aging & Disease. Aug2023, Vol. 14 Issue 4, p1441-1457. 17p.
Autor:
Yunjuan Nie, Teja Srinivas Nirujogi, Ravi Ranjan, Brenda F. Reader, Sangwoon Chung, Megan N. Ballinger, Joshua A. Englert, John W. Christman, Manjula Karpurapu
Publikováno v:
Journal of Innate Immunity, Pp 1-11 (2020)
Pulmonary macrophages play a critical role in the recognition of pathogens, initiation of host defense via inflammation, clearance of pathogens from the airways, and resolution of inflammation. Recently, we have shown a pivotal role for the nuclear f
Externí odkaz:
https://doaj.org/article/34d438b285e4453f8c0bccbc8c4f182f
Autor:
Junjie Liang, Shanshan Han, Chao Ye, Haimeng Zhu, Jiajun Wu, Yunjuan Nie, Gaoshang Chai, Peng Zhao, Dengxin Zhang
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 512 (2023)
Postoperative cognitive dysfunction (POCD), an important postoperative neurological complication, is very common and has an elevated incidence in elderly patients. Sevoflurane, an inhaled anesthetic, has been demonstrated to be associated with POCD i
Externí odkaz:
https://doaj.org/article/3bfe9da2422d445dbddc415c44873963
Autor:
Xue Wang, Waseem Hassan, Jing Zhao, Sahar Bakht, Yunjuan Nie, Ying Wang, Qingfeng Pang, Zhaohui Huang
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-8 (2019)
Abstract Hepatocyte nuclear factor-1 alpha (HNF-1α) is a transcription factor expressed predominantly in the liver among other organs. Structurally, it contains POU-homeodomain that binds to DNA and form proteins that help in maintaining cellular ho
Externí odkaz:
https://doaj.org/article/3feddfa7ae404e278e51a00f1486c4b7
Autor:
Yunjuan Nie, Kaikai Yu, Boyu Li, Yudong Hu, Hui Zhang, Ruiting Xin, Yue Xiong, Peng Zhao, Gaoshang Chai
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 4, Pp 377-384 (2019)
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease characterized by inflammation, multifocal fibrotic lesions and excessive collagen deposition with limited therapies. As a major bioactive compound in garlic, S-allyl-l-cyste
Externí odkaz:
https://doaj.org/article/ae32e74361554f1794bf7b4d4613d00b
Autor:
Jun Wang, Lei Sun, Yunjuan Nie, Shixin Duan, Tao Zhang, Weiwei Wang, Richard D. Ye, Shangwei Hou, Feng Qian
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and lethal interstitial lung disease characterized by consistent pulmonary inflammation. Although protein kinase C delta (PKCδ) is involved in broad scope cellular response, the role of P
Externí odkaz:
https://doaj.org/article/0a1a78bb260349c99e62d7d8c8ed3c64
Publikováno v:
Innate Immunity, Vol 25 (2019)
Abstract Idiopathic pulmonary fibrosis is a progressive interstitial pneumonia characterised by fibroblast accumulation, collagen deposition and extracellular matrix (ECM) remodelling. It was reported that Akt1 mediated idiopathic pulmonary fibrosis
Externí odkaz:
https://doaj.org/article/441b028d08c142b7a9801ccc57d70213