Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Yunju Jo"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 10, Pp 2113-2126 (2024)
Abstract Cancer immunotherapy aims to initiate or amplify immune responses that eliminate cancer cells and create immune memory to prevent relapse. Immune checkpoint inhibitors (ICIs), which target coinhibitory receptors on immune effector cells, suc
Externí odkaz:
https://doaj.org/article/9c333c08878043bf93cd76228a3caa8d
Autor:
Min‐gu Kang, Ji Yeon Baek, Yunju Jo, Dongryeol Ryu, Il‐Young Jang, Hee‐Won Jung, Beom‐Jun Kim
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 2134-2142 (2024)
Abstract Background Uric acid (UA), the terminal breakdown product of purine metabolism, possesses contradictory roles, functioning both as an inflammatory mediator and as an antioxidant. Its clinical relevance, particularly in geriatric populations,
Externí odkaz:
https://doaj.org/article/6973bbcf42f74f1f877b8f6ee447729e
Autor:
Yan Zhang, Shibo Wei, Eun-Ju Jin, Yunju Jo, Chang-Myung Oh, Gyu-Un Bae, Jong-Sun Kang, Dongryeol Ryu
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 4, Pp 487-502 (2024)
Cardiovascular diseases (CVDs) and metabolic disorders stand as formidable challenges that significantly impact the clinical outcomes and living quality for afflicted individuals. An intricate comprehension of the underlying mechanisms is paramount f
Externí odkaz:
https://doaj.org/article/68881e4d8d584deaa3e4a4e7bfcc317c
Autor:
Eun-Ho Lee, Jae-Ho Lee, Do-Young Kim, Young-Seung Lee, Yunju Jo, Tam Dao, Kyung Eun Kim, Dae-Kyu Song, Ji Hae Seo, Young-Kyo Seo, Je Kyung Seong, Changjong Moon, Eugene Han, Mi Kyung Kim, Seungwan Ryu, Minsang Shin, Gu Seob Roh, Hye Ra Jung, Timothy F. Osborne, Dongryeol Ryu, Tae-Il Jeon, Seung-Soon Im
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 4, Pp 1001-1012 (2024)
Abstract Sterol regulatory element-binding protein (SREBP)-1c is involved in cellular lipid homeostasis and cholesterol biosynthesis and is highly increased in nonalcoholic steatohepatitis (NASH). However, the molecular mechanism by which SREBP-1c re
Externí odkaz:
https://doaj.org/article/80e78e3a38c74985adacee329525bee4
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Diabetes mellitus is a complex chronic disease, considered as one of the most common metabolic disorders worldwide, posing a major threat to global public health. Ferroptosis emerges as a novel mechanism of programmed cell death, distinct from apopto
Externí odkaz:
https://doaj.org/article/11b0f6499093496f9310948089de48f3
Autor:
Dong-hee Lee, Hyejin Ahn, Hye-In Sim, Eunji Choi, Seunghyun Choi, Yunju Jo, Bohwan Yun, Hyun Kyu Song, Soo Jin Oh, Kaori Denda-Nagai, Chan-Sik Park, Tatsuro Irimura, Yoon Park, Hyung-seung Jin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Immunotherapy has significantly advanced cancer treatments, but many patients do not respond to it, partly due to immunosuppressive mechanisms used by tumor cells. These cells employ immunosuppressive ligands to evade detection an
Externí odkaz:
https://doaj.org/article/5a2155d0c9c541b7b2a52446c3747bb0
Autor:
Hyun-Jun Jang, Yo Han Lee, Tam Dao, Yunju Jo, Keon Woo Khim, Hye-jin Eom, Ju Eun Lee, Yi Jin Song, Sun Sil Choi, Kieun Park, Haneul Ji, Young Chan Chae, Kyungjae Myung, Hongtae Kim, Dongryeol Ryu, Neung Hwa Park, Sung Ho Park, Jang Hyun Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1720-1733 (2023)
Abstract Autophagy functions in cellular quality control and metabolic regulation. Dysregulation of autophagy is one of the major pathogenic factors contributing to the progression of nonalcoholic fatty liver disease (NAFLD). Autophagy is involved in
Externí odkaz:
https://doaj.org/article/d56a7edfec494605a5705df2ce84a1d6
Autor:
Thanh T. Nguyen, Shibo Wei, Thu Ha Nguyen, Yunju Jo, Yan Zhang, Wonyoung Park, Karim Gariani, Chang-Myung Oh, Hyeon Ho Kim, Ki-Tae Ha, Kyu Sang Park, Raekil Park, In-Kyu Lee, Minho Shong, Riekelt H. Houtkooper, Dongryeol Ryu
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1595-1619 (2023)
Abstract Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production, support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate. Evidence has shown mitochondria as points of convergence fo
Externí odkaz:
https://doaj.org/article/69b80a65f8c146e29d7c4b1cbf007852
Autor:
Jibeom Lee, Hyeonhui Kim, Yun-Won Kang, Yumin Kim, Moon-young Park, Ji-Hong Song, Yunju Jo, Tam Dao, Dongryeol Ryu, Junguee Lee, Chang-Myung Oh, Sangkyu Park
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 7, Pp 1479-1491 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) is a serious metabolic disorder characterized by excess fat accumulation in the liver. Over the past decade, NAFLD prevalence and incidence have risen globally. There are currently no effective licens
Externí odkaz:
https://doaj.org/article/14d937e796a64eba8e1a65f80eae7ab6
Autor:
Seong-Yeol Kim, Minji Song, Yunju Jo, Youngjae Jung, Heecheon You, Myoung-Hwan Ko, Gi-Wook Kim
Publikováno v:
JMIR Serious Games, Vol 11, p e49216 (2023)
BackgroundArticulation disorder decreases the clarity of language and causes a decrease in children’s learning and social ability. The demand for non–face-to-face treatment is increasing owing to the limited number of therapists and geographical
Externí odkaz:
https://doaj.org/article/6ddb89160ff44a9bb65551aba096a21f