Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Yunjian Pan"'
Autor:
Yue Zhao, Jian Gao, Jun Wang, Fanfan Fan, Chao Cheng, Danwen Qian, Ran Guo, Yang Zhang, Ting Ye, Marcellus Augustine, Yicong Lin, Jun Shang, Hang Li, Yunjian Pan, Qingyuan Huang, Haiqing Chen, Han Han, Zhendong Gao, Qiming Wang, Shiyue Zhang, Mou Zhang, Fangqiu Fu, Yueren Yan, Shanila Fernandez Patel, Roberto Vendramin, Hui Yuan, Yawei Zhang, Jiaqing Xiang, Hong Hu, Yihua Sun, Yuan Li, Kevin Litchfield, Zhiwei Cao, Haiquan Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Multiple synchronous lung cancers (MSLCs) constitute a unique subtype of lung cancer. To explore the genomic and immune heterogeneity across different pathological stages of MSLCs, we analyse 16 MSLCs from 8 patients using single-cell RNA-se
Externí odkaz:
https://doaj.org/article/671defe093864fdc89816bdc093aaebf
Autor:
Zhaoyuan Fang, Xiangkun Han, Yueqing Chen, Xinyuan Tong, Yun Xue, Shun Yao, Shijie Tang, Yunjian Pan, Yihua Sun, Xue Wang, Yujuan Jin, Haiquan Chen, Liang Hu, Lijian Hui, Lin Li, Luonan Chen, Hongbin Ji
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Lkb1 deficiency confers the Kras-mutant lung cancer with strong plasticity and the potential for adeno-to-squamous transdifferentiation (AST). However, it remains largely unknown how Lkb1 deficiency dynamically regulates AST. Using the class
Externí odkaz:
https://doaj.org/article/1de59c754db845e4b4f94de55da2e5fb
Autor:
Chongze Yuan, Haojie Chen, Shiqi Tu, Hsin-Yi Huang, Yunjian Pan, Xiuqi Gui, Muyu Kuang, Xuxia Shen, Qiang Zheng, Yang Zhang, Chao Cheng, Hui Hong, Xiaoting Tao, Yizhou Peng, Xingxin Yao, Feilong Meng, Hongbin Ji, Zhen Shao, Yihua Sun
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-26 (2021)
Abstract Background Lung adenocarcinoma (LUAD) is a highly malignant and heterogeneous tumor that involves various oncogenic genetic alterations. Epigenetic processes play important roles in lung cancer development. However, the variation in enhancer
Externí odkaz:
https://doaj.org/article/c0244b8b532749f2808712292775ae05
Autor:
Haiquan Chen, Jian Carrot-Zhang, Yue Zhao, Haichuan Hu, Samuel S. Freeman, Su Yu, Gavin Ha, Alison M. Taylor, Ashton C. Berger, Lindsay Westlake, Yuanting Zheng, Jiyang Zhang, Aruna Ramachandran, Qiang Zheng, Yunjian Pan, Difan Zheng, Shanbo Zheng, Chao Cheng, Muyu Kuang, Xiaoyan Zhou, Yang Zhang, Hang Li, Ting Ye, Yuan Ma, Zhendong Gao, Xiaoting Tao, Han Han, Jun Shang, Ying Yu, Ding Bao, Yechao Huang, Xiangnan Li, Yawei Zhang, Jiaqing Xiang, Yihua Sun, Yuan Li, Andrew D. Cherniack, Joshua D. Campbell, Leming Shi, Matthew Meyerson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-6 (2019)
The genomic and immune landscape of pre-invasive lung adenocarcinoma is poorly understood. Here, the authors perform exome and transcriptome sequencing on precursor legions and invasive lung adenocarcinomas, identifying recurrently mutated genes in p
Externí odkaz:
https://doaj.org/article/4a9c53d05b3d4f2bb8b67fc34b59ad6c
Autor:
Hang Li, Bin Li, Yunjian Pan, Yang Zhang, Jiaqing Xiang, Yawei Zhang, Yihua Sun, Xiang Yu, Wei He, Hong Hu
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundSurgical resection is often the preferred treatment for non-small cell lung cancer (NSCLC) patients. Predictive biomarkers after surgery can help monitoring and treating patients promptly, so as to improve the clinical outcome. In this stud
Externí odkaz:
https://doaj.org/article/7669c727f0b04331885f1b95a01ac953
Autor:
Sirui Zhang, Yufang Bao, Xianfeng Shen, Yunjian Pan, Yue Sun, Man Xiao, Kexuan Chen, Huanhuan Wei, Ji Zuo, David Saffen, Wei-Xing Zong, Yihua Sun, Zefeng Wang, Yongbo Wang
Publikováno v:
EBioMedicine, Vol 61, Iss , Pp 103067- (2020)
Background: RNA splicing defects are emerging molecular hallmarks of cancer. The gene encoding splicing factor RNA binding motif protein 10 (RBM10) has been found frequently mutated in various types of cancer, particularly lung adenocarcinoma (LUAD),
Externí odkaz:
https://doaj.org/article/29f1f99692e3423ca848ddddb7179f19
Autor:
Xiaoyang Luo, Shanbo Zheng, Quan Liu, Shengping Wang, Yuan Li, Lei Shen, Guodong Li, Wentao Li, Yanping Zhao, Huilin Xu, Jing Wang, Xiaohua Liu, Yunjian Pan, Hong Hu, Yihua Sun, Haiyan Yang, Su Xu, Haiquan Chen
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 485-490 (2017)
OBJECTIVE: We investigated the efficacy of early lung cancer screening with low-dose spiral computed tomography(LDCT) in both smokers and nonsmokers based on the current situation of community health service, with integration of superior resources of
Externí odkaz:
https://doaj.org/article/4b690cf3c7444c91885eb52f6fb51589
Autor:
Lei Wang, Haichuan Hu, Yunjian Pan, Rui Wang, Yuan Li, Lei Shen, Yongfu Yu, Hang Li, Deng Cai, Yihua Sun, Haiquan Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88291 (2014)
PurposePIK3CA gene encoding a catalytic subunit of the phosphatidylinositol-3-kinase (PI3K) is mutated and/or amplified in various neoplasia, including lung cancer. Here we investigated PIK3CA gene alterations, the expression of core components of PI
Externí odkaz:
https://doaj.org/article/3b71e47ac6ad47658a21322e99962960
Autor:
Yuan Li, Yunjian Pan, Rui Wang, Yihua Sun, Haichuan Hu, Xuxia Shen, Yongming Lu, Lei Shen, Xiongzeng Zhu, Haiquan Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69016 (2013)
Approximately 3-7% of non-small cell lung cancers harbor an anaplastic lymphoma kinase (ALK) gene fusion, constituting a new molecular subtype of lung cancer that responds to crizotinib, an ALK inhibitor. Although previous studies have evaluated ALK-
Externí odkaz:
https://doaj.org/article/c3662c4ab0d04a45bdbe260c0026ac9f
Autor:
Yongbo Wang, Zefeng Wang, Wei-Xing Zong, Ji Zuo, Yunpeng Ren, Ning Wang, Yueren Yan, Yunjian Pan, Xiaoyu Zhang, Sirui Zhang, Yufang Bao
Supplementary Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc6e5c7757cc5fc4eaa248234efbd3a
https://doi.org/10.1158/0008-5472.22730652.v1
https://doi.org/10.1158/0008-5472.22730652.v1