Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Yunhua Gao"'
Autor:
Xueli Peng, Yuning Ma, Chenxin Yan, Xiaocen Wei, Linlin Zhang, Hehe Jiang, Yuxia Ma, Suohui Zhang, Mengzhen Xing, Yunhua Gao
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1022 (2024)
Skin pigmentation typically arises from the excessive secretion and accumulation of melanin, resulting in a darker complexion compared to normal skin. Currently, the local application of chemical drugs is a first-line strategy for pigmentation disord
Externí odkaz:
https://doaj.org/article/c28cbf65aaaa407283088d79c24efa38
Autor:
Yongshu Li, Winnie Wailing TAM, Yuanyuan Yu, Zhenjian Zhuo, Zhichao Xue, Chiman Tsang, Xiaoting Qiao, Xiaokang Wang, Weijing Wang, Yongyi Li, Yanyang Tu, Yunhua Gao
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Biomarkers are detectable molecules that can reflect specific physiological states of cells, organs, and organisms and therefore be regarded as indicators for specific diseases. And the discovery of biomarkers plays an essential role in canc
Externí odkaz:
https://doaj.org/article/6d0abc9f719840558223a396883d7896
Autor:
Yongzhuo Zhang, Xia Wang, Chunyan Niu, Di Wang, Qingfei Shen, Yunhua Gao, Haiwei Zhou, Yujing Zhang, Yan Zhang, Lianhua Dong
Publikováno v:
Biosafety and Health, Vol 4, Iss 5, Pp 321-329 (2022)
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to unprecedented social and economic disruption. Many nucleic acid testing (NAT) laboratories in China have been established to control the epidemic better. T
Externí odkaz:
https://doaj.org/article/0b298360411f476c8689a7430065945b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Illuminating DNA and RNA dynamics in live cell can elucidate their life cycle and related biochemical activities. Various protocols have been developed for labeling the regions of interest in DNA and RNA molecules with different types of fluorescent
Externí odkaz:
https://doaj.org/article/9e3db40fda524400bacc192c398f7531
Autor:
Baorui Wang, Suohui Zhang, Guozhong Yang, Zequan Zhou, Mengzhen Xing, Han Liu, Aguo Cheng, Yunhua Gao
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 1, Pp 100776- (2023)
To reduce mucosal damage in the gastrointestinal tract caused by aspirin, we developed a dissolvable polymeric microneedle (MN) patch loaded with aspirin. Biodegradable polymers provide mechanical strength to the MNs. The MN tips punctured the cuticl
Externí odkaz:
https://doaj.org/article/d88ce4c0222d47d2bc9f13dfcf8ad172
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
Verticillium nonalfalfae and V. albo-atrum are notorious pathogenic fungi that cause a destructive vascular disease called Verticillium wilt worldwide. Thus, timely and quantitative monitoring of fungal progression is highly desirable for early diagn
Externí odkaz:
https://doaj.org/article/8c92552477bd456c986781c21993fc05
Autor:
Yongshu Li, Jing Zhao, Zhichao Xue, Chiman Tsang, Xiaoting Qiao, Lianhua Dong, Huijie Li, Yi Yang, Bin Yu, Yunhua Gao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Aptamers are short single-strand oligonucleotides that can form secondary and tertiary structures, fitting targets with high affinity and specificity. They are so-called “chemical antibodies” and can target specific biomarkers in both diagnostic
Externí odkaz:
https://doaj.org/article/1548d16d853d4f3da1d4e14eca011ff1
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 5, Pp 612-622 (2021)
Coated microneedles (MNs) are widely used for delivering biopharmaceuticals. In this study, a novel gel encapsulated coated MNs (GEC-MNs) was developed. The water-soluble drug coating was encapsulated with sodium alginate (SA) in situ complexation ge
Externí odkaz:
https://doaj.org/article/7fa5ea5ec90c4690b1156ae495746a0d
Publikováno v:
Polymers, Vol 15, Iss 15, p 3296 (2023)
Excessive melanin deposition in the skin leads to various skin pigmentation diseases, such as chloasma and age spots. The deposition is induced by several factors, including tyrosinase activities and ultraviolet-induced oxidative stress. Herein, we p
Externí odkaz:
https://doaj.org/article/ef4246be219b4624be1c746b3f13dac2
Autor:
Mengzhen Xing, Yuning Ma, Xiaocen Wei, Chen Chen, Xueli Peng, Yuxia Ma, Bingwen Liang, Yunhua Gao, Jibiao Wu
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 2007 (2023)
Poor transdermal permeability limits the possibility of most drug delivery through the skin. Auxiliary permeable microneedles (AP-MNs) with a three-dimensional network structure can effectively break the skin stratum corneum barrier and assist in the
Externí odkaz:
https://doaj.org/article/5ae585d298044fd3b23ccee7bb683816