Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yunhong Hotta"'
Autor:
Masao Doi, Iori Murai, Sumihiro Kunisue, Genzui Setsu, Naohiro Uchio, Rina Tanaka, Sakurako Kobayashi, Hiroyuki Shimatani, Hida Hayashi, Hsu-Wen Chao, Yuuki Nakagawa, Yukari Takahashi, Yunhong Hotta, Jun-ichirou Yasunaga, Masao Matsuoka, Michael H. Hastings, Hiroshi Kiyonari, Hitoshi Okamura
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The suprachiasmatic nucleus (SCN) is the central regulator of circadian rhythms. Here the authors identify mouse Gpr176 as a pace modulator of this circadian clock and characterize its mode of action as coupling to Gz rather than Gi subunits.
Externí odkaz:
https://doaj.org/article/c16b11b6441e475eb897bd5b32fd2eac
Autor:
Masaki Yamamoto, So Iwata, Takuya Kobayashi, Yunhong Hotta, Kunio Hirata, Kazushi Morimoto, Shuh Narumiya, Ryoji Suno, Keitaro Yamashita
Publikováno v:
Nature chemical biology. 15(1)
Prostanoids are a series of bioactive lipid metabolites that function in an autacoid manner via activation of cognate G-protein-coupled receptors (GPCRs). Here, we report the crystal structure of human prostaglandin (PG) E receptor subtype EP3 bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aac4ff572dfce8861bc9e644cad6f72
https://pubmed.ncbi.nlm.nih.gov/30510192
https://pubmed.ncbi.nlm.nih.gov/30510192
Autor:
Yukari Takahashi, Ryo Morimoto, Sadayoshi Ito, Hironobu Sasano, Yasuhiro Nakamura, Yunhong Hotta, Kei Takase, Hitoshi Okamura, Masao Doi, Takashi Maekawa, Jean-Michel Fustin, Motomi Tainaka, Fumitoshi Satoh
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E257-E262
[Context]: Therapeutic management of primary aldosteronism requires accurate differentiation between aldosterone-producing adenoma (APA) and idiopathic hyperaldosteronism (IHA). However, little is known about the molecular features that delineate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58f7a4afbee569ba84d8e3024d6df34
https://doi.org/10.1210/jc.2013-3279
https://doi.org/10.1210/jc.2013-3279
Autor:
Hiroshi Kiyonari, Hsu Wen Chao, Hitoshi Okamura, Yuuki Nakagawa, Naohiro Uchio, Yukari Takahashi, Yunhong Hotta, Masao Matsuoka, Sakurako Kobayashi, Rina Tanaka, Michael H. Hastings, Iori Murai, Hida Hayashi, Sumihiro Kunisue, Jun-ichirou Yasunaga, Masao Doi, Genzui Setsu, Hiroyuki Shimatani
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
G-protein-coupled receptors (GPCRs) participate in a broad range of physiological functions. A priority for fundamental and clinical research, therefore, is to decipher the function of over 140 remaining orphan GPCRs. The suprachiasmatic nucleus (SCN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0ab3c6ad9471f0e4fe917467db70a8
http://europepmc.org/articles/PMC4757782
http://europepmc.org/articles/PMC4757782
Autor:
Yunhong Hotta, Hida Hayashi, Iori Murai, Koki Yamamura, Takumi Ota, Hitoshi Okamura, Masao Doi, Rie Komatsu
Publikováno v:
Molecular and cellular endocrinology. 382(1)
The enzyme 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD) is essential for the biosynthesis of all active steroid hormones, such as those secreted from the adrenal gland, testis, ovary, skin and placenta. The 3β-HSD enzymes exist in multiple i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd374d29dd127b497cb15ba7a4e94f80
https://pubmed.ncbi.nlm.nih.gov/24075909
https://pubmed.ncbi.nlm.nih.gov/24075909