Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yungki Park"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Although genome-wide association studies (GWAS) have identified multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucleotide polymorphisms
Externí odkaz:
https://doaj.org/article/098fccfca55a417aaff71d5905676db1
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235857 (2020)
ObjectiveThe risk loci for juvenile idiopathic arthritis (JIA) consist of extended haplotypes that include functional elements in addition to canonical coding genes. As with most autoimmune diseases, the risk haplotypes for JIA are highly enriched fo
Externí odkaz:
https://doaj.org/article/e2cb71c15f6d44449d2a8e3ad1bd8bf9
Autor:
Sophie Belin, Jacob Herron, Jordan J. S. VerPlank, Yungki Park, Laura M. Feltri, Yannick Poitelon
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Externí odkaz:
https://doaj.org/article/477f31a8d677409ab4ccd6b4a738bdcd
Autor:
Sophie Belin, Jacob Herron, Jordan J. S. VerPlank, Yungki Park, Laura M. Feltri, Yannick Poitelon
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Schwann cells (SCs) are exquisitely sensitive to the elasticity of their environment and their differentiation and capacity to myelinate depend on the transduction of mechanical stimuli by YAP and TAZ. YAP/TAZ, in concert with other transcription fac
Externí odkaz:
https://doaj.org/article/0db3c49986044f7daedbf117529378cc
Publikováno v:
PLoS Biology, Vol 11, Iss 8, p e1001624 (2013)
Myelination of the central nervous system (CNS) is critical to vertebrate nervous systems for efficient neural signaling. CNS myelination occurs as oligodendrocytes terminally differentiate, a process regulated in part by the myelin regulatory factor
Externí odkaz:
https://doaj.org/article/ba3fbe3bd85446cb85e61326533636f9
Publikováno v:
Human Molecular Genetics. 32:835-846
Olig2 is a basic helix–loop–helix transcription factor that plays a critical role in the central nervous system. It directs the specification of motor neurons and oligodendrocyte precursor cells (OPCs) from neural progenitors and the subsequent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6413d879d00e7896326beac50e5b42
https://doi.org/10.1093/hmg/ddac249
https://doi.org/10.1093/hmg/ddac249
IntroductionAlthough genome-wide association studies (GWAS) multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucleotide polymorphisms (SNPs) on the disease ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d7b439e983881e5b6dec741ed74911
https://doi.org/10.1101/2022.03.07.483040
https://doi.org/10.1101/2022.03.07.483040
Autor:
Hongjoo An, Randall S. Shearer, Dongkyeong Kim, Jin-ok Choi, Mohamed Sharif, Yungki Park, Sun Ryu, Chuandong Fan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Mapping enhancers to genes is a fundamental goal of modern biology. We have developed an innovative strategy that maps enhancers to genes in a principled manner. We illustrate its power by applying it to Myrf. Despite being a master regulator of olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07239240d0a0105b5bcbd672f837026
http://link.springer.com/article/10.1038/s41598-019-47521-w
http://link.springer.com/article/10.1038/s41598-019-47521-w
Publikováno v:
Hum Mol Genet
Oligodendrocytes (OLs) produce myelin in the central nervous system (CNS), which accelerates the propagation of action potentials and supports axonal integrity. As a major component of CNS myelin, proteolipid protein 1 (Plp1) is indispensable for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6756919d56ab67b5ce9bd02c0751e5b4
https://pubmed.ncbi.nlm.nih.gov/34230963
https://pubmed.ncbi.nlm.nih.gov/34230963
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Myrf is a membrane-bound transcription factor that plays a key role in various biological processes. The Intramolecular Chaperone Auto-processing (ICA) domain of Myrf forms a homo-trimer, which carries out the auto-cleavage of Myrf. The ICA homo-trim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655a21431ed57f53c0e8ad0de0e05557
https://doi.org/10.1038/s41598-020-57593-8
https://doi.org/10.1038/s41598-020-57593-8