Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yungdae Yun"'
Publikováno v:
Molecules and Cells
Lck-interacting transmembrane adaptor 1 (LIME) has been previously identified as a raft-associated transmembrane protein expressed predominantly in T and B lymphocytes. Although LIME is shown to transduce the immunoreceptor signaling and immunologica
Publikováno v:
Immunology & Cell Biology. 97:877-887
Previously, we reported induced expression of the p190 Rho guanine nucleotide exchange factor (p190RhoGEF, ARHGEF28) following CD40 stimulation of B cells isolated from mouse spleen. We also reported that p190RhoGEF and a downstream effector molecule
Publikováno v:
Molecules & Cells (Elsevier B.V); Nov2020, Vol. 43 Issue 11, p921-934, 14p
Publikováno v:
Toxicology and Applied Pharmacology. 274:462-470
Th1 lymphocytes are predominant in atherosclerotic lesions. However, mechanisms involved in the Th1 predominance are unknown. We have investigated the possibility of Th1 lymphocyte recruitment in a cholesterol-rich milieu. A high cholesterol diet res
Publikováno v:
Molecules and Cells. 33:407-414
Lck Interacting Membrane protein (LIME) was previously characterized as a transmembrane adaptor protein mediating TCR-dependent T cell activation. Here, we show that LIME associates with Vav in response to TCR stimulation and is required for Vav guan
Publikováno v:
Blood. 109:5122-5128
Lck-interacting adaptor protein/Rlk/Itk-binding protein (Lad/RIBP) was previously identified as an adaptor protein involved in TCR-mediated T-cell activation. To elucidate the functions of Lad further, we here performed yeast 2-hybrid screening using
Autor:
Seok Jin Nam, Sung-Do Kim, K-H Lee, Yungdae Yun, Sang Min Park, E. S. Lee, Min Ki Lee, Shin Ahn, Byeong Woo Park, D Noh
Publikováno v:
Annals of Oncology. 18:173-182
Background: Although most of the literature about health-related quality of life (HRQoL) focuses on breast cancer patients, few studies compared the HRQoL in disease-free breast cancer survivors with that of the general population. Materials and meth
Autor:
Haein Park, Sungmun Choi, Seungin Kim, Eok Soo Oh, Soojin Kwon, Inn-Oc Han, Yungdae Yun, Jae Youn Yi, Eun Jung Lee
Publikováno v:
Journal of Biological Chemistry. 280:42573-42579
The syndecans are known to form homologous oligomers that may be important for their functions. We have therefore determined the role of oligomerization of syndecan-2 and syndecan-4. A series of glutathione S-transferase-syndecan-2 and syndecan-4 chi
Publikováno v:
Biochemical Journal. 388:7-15
Double-strand breaks (DSBs) of chromosomal DNA trigger the cellular response that activates the pathways for DNA repair and cell-cycle checkpoints, and sometimes the pathways leading to cell death if the damage is too severe to be tolerated. Evidence
Autor:
Hyunsook Lee, Myoungsun Son, Yungdae Yun, Eun Mi Hur, Changwon Park, Young Bong Choi, Ok Hee Lee
Publikováno v:
The Journal of Experimental Medicine
In this study, we identify and characterize a novel transmembrane adaptor protein, designated Lck-interacting membrane protein (LIME), as a binding partner of the Lck Src homology (SH)2 domain. LIME possesses a short extracellular domain, a transmemb