Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yung-Wen Chiu"'
Publikováno v:
Folia Pharmacologica Japonica. 158:21-25
The production of amyloid β peptide (Aβ) is an important process relating to the pathogenesis of Alzheimer disease (AD). It is widely known that the sequential cleavage of amyloid precursor protein (APP) by β- and γ-secretases lead to the product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a18f36f1393cd585390282c4e33188
https://doi.org/10.1254/fpj.22081
https://doi.org/10.1254/fpj.22081
Autor:
Reito Nakamura, Ikumi Tomizawa, Atsushi Iwai, Tetsuo Ikeda, Kota Hirayama, Yung Wen Chiu, Takanobu Suzuki, Airi Tarutani, Tatsuo Mano, Atsushi Iwata, Tatsushi Toda, Youhei Sohma, Motomu Kanai, Yukiko Hori, Taisuke Tomita
Publikováno v:
FASEB Journal; Dec2023, Vol. 37 Issue 12, p1-12, 12p
Autor:
Kazunori Kikuchi, Sho Takatori, Yung Wen Chiu, Miyabishara Yokoyama, Makoto Arita, Taisuke Tomita, Yuki Sudo, Kiwami Kidana, Takuya Tatebe, Yukiko Hori
Publikováno v:
J Neurosci
Alzheimer disease (AD) is characterized by the extensive deposition of amyloid-β peptide (Aβ) in the brain. Brain Aβ level is regulated by a balance between Aβ production and clearance. The clearance rate of Aβ is decreased in the brains of spor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599a3f8017b710798ad62f3b15bb9113
https://doi.org/10.1523/jneurosci.2595-20.2021
https://doi.org/10.1523/jneurosci.2595-20.2021
Publikováno v:
The FASEB Journal. 34:16383-16396
BackgroundSeveral lines of evidence suggest that the aggregation and deposition of amyloid-β peptide (Aβ) initiate the pathology of Alzheimer disease (AD). Recently, a genome- wide association study demonstrated that a single-nucleotide polymorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a644af9e8b96b317a506fb8ded7f64c8
https://doi.org/10.1096/fj.202001510r
https://doi.org/10.1096/fj.202001510r
Autor:
Yung Wen Chiu, Norikazu Hara, Taisuke Tomita, Takeshi Ikeuchi, Yukiko Hori, Haruaki Sato, Ihori Ebinuma
Publikováno v:
The FASEB Journal. 34:7661-7674
The aberrant metabolism of amyloid β peptide (Aβ) has been implicated in the etiology of Alzheimer disease (AD). Aβ is produced via the sequential cleavage of amyloid precursor protein (APP) by β- and γ-secretases. However, the precise regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bb708d709de0703d9eff1bbf70c320
https://doi.org/10.1096/fj.201902966rr
https://doi.org/10.1096/fj.201902966rr
Autor:
Reiko Koike, Taisuke Tomita, Yusuke Shimizu, Takanobu Suzuki, Motomu Kanai, Yung Wen Chiu, Sho Takatori, Yukiko Hori, Wenbo Wang, Shuta Ozawa, Tohru Fukuyama, Atsuhiko Taniguchi, Youhei Sohma, Satoshi Yokoshima
Publikováno v:
Brain : a journal of neurology. 144(6)
Amyloid formation and the deposition of the amyloid-β peptide are hallmarks of Alzheimer’s disease pathogenesis. Immunotherapies using anti-amyloid-β antibodies have been highlighted as a promising approach for the prevention and treatment of Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d96ef4b85b8a6686aff04940304df2e
https://pubmed.ncbi.nlm.nih.gov/36189373
https://pubmed.ncbi.nlm.nih.gov/36189373
Autor:
Kazunori Kikuchi, Takuya Tatebe, Yuki Sudo, Miyabishara Yokoyama, Kiwami Kidana, Yung Wen Chiu, Sho Takatori, Makoto Arita, Yukiko Hori, Taisuke Tomita
Publikováno v:
Journal of Neuroscience; 7/14/2021, Vol. 41 Issue 28, p6173-6185, 13p
Autor:
Shin-ichi Hisanaga, Yung Wen Chiu, Yukiko Hori, Kotaro Furusawa, Mitsunori Fukuda, Toshiyuki Takasugi, Taisuke Tomita
Publikováno v:
J Biol Chem
A hallmark of Alzheimer's disease (AD) pathology is the appearance of senile plaques, which are composed of β-amyloid (Aβ) peptides. Aβ is produced by sequential cleavages of amyloid precursor protein (APP) by β- and γ-secretases. These cleavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3014d53ef88d39eee63530738da81f94
https://pubmed.ncbi.nlm.nih.gov/31138646
https://pubmed.ncbi.nlm.nih.gov/31138646
Publikováno v:
Journal of neurochemistry. 147(1)
The aberrant metabolism of amyloid-β protein (Aβ) in the human brain has been implicated in the etiology of Alzheimer disease (AD). γ-Secretase is the enzyme that generates various forms of Aβ, such as Aβ40 and Aβ42, the latter being an aggrega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc144918daba911d8d16cc9be42aa227
https://pubmed.ncbi.nlm.nih.gov/29851073
https://pubmed.ncbi.nlm.nih.gov/29851073
Autor:
Yung-Jung Liu, Han-Chung Wu, Chen-Wen Wu, Chin-Tarng Lin, Jeng-Jie Lee, Yet Peng, Yung-Wen Chiu, Yu-Ju Lin, Sung-Tzu Liang
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 83(6)
A membrane invasion culture system was used to study the ability of EBV to enhance invasion and migration of nasopharyngeal carcinoma (NPC) cells. Semi-reverse transcriptase-PCR analysis of matrix proteinases and angiogenic factors from EBV-infected,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d394ed22ccc2cde23afff32dbe87f03
https://pubmed.ncbi.nlm.nih.gov/12808115
https://pubmed.ncbi.nlm.nih.gov/12808115