Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Yung-Tsi Bolon"'
Autor:
Guru Subramanian Guru Murthy, Tao Zhang, Yung-Tsi Bolon, Stephen Spellman, Jing Dong, Paul Auer, Wael Saber
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-4 (2024)
Abstract Disease relapse remains a major barrier to success after allogeneic hematopoietic cell transplantation (allo-HCT) in myelodysplastic neoplasms (MDS). While certain high risk genomic alterations are associated with increased risk of relapse,
Externí odkaz:
https://doaj.org/article/4237d40728e34d7aa04b78365928ddf2
Autor:
Johannes Schetelig, Henning Baldauf, Falk Heidenreich, Jorinde D. Hoogenboom, Stephen R. Spellman, Alexander Kulagin, Thomas Schroeder, Henrik Sengeloev, Peter Dreger, Edouard Forcade, Jan Vydra, Eva Maria Wagner-Drouet, Goda Choi, Shankara Paneesha, Nuno A. A. Miranda, Alina Tanase, Liesbeth C. de Wreede, Vinzenz Lange, Alexander H. Schmidt, Jürgen Sauter, Joshua A. Fein, Yung-Tsi Bolon, Meilun He, Steven G. E. Marsh, Shahinaz M. Gadalla, Sophie Paczesny, Annalisa Ruggeri, Christian Chabannon, Katharina Fleischhauer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Optimizing natural killer (NK) cell alloreactivity could further improve outcome after allogeneic hematopoietic cell transplantation (alloHCT). The donor’s Killer-cell Immunoglobulin-like Receptor (KIR) genotype may provide important information in
Externí odkaz:
https://doaj.org/article/2b878953d63c4541a7adf722c396e6d2
Autor:
Abeer Madbouly, Yung-Tsi Bolon
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Race, ethnicity, and ancestry are terms that are often misinterpreted and/or used interchangeably. There is lack of consensus in the scientific literature on the definition of these terms and insufficient guidelines on the proper classification, coll
Externí odkaz:
https://doaj.org/article/e780c5026fc54f0595131630cd0be281
Autor:
Tao Zhang, Paul Auer, Jing Dong, Corey Cutler, Amy E. Dezern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Karen-Sue Carlson, Stephen Spellman, Yung-Tsi Bolon, Wael Saber
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Recurrent mutations in TP53, RAS pathway and JAK2 genes were shown to be highly prognostic of allogeneic hematopoietic cell transplant (alloHCT) outcomes in myelodysplastic syndromes (MDS). However, a significant proportion of MDS patients h
Externí odkaz:
https://doaj.org/article/070e43d5f7fa42d6b57cf3d32d7704b7
Autor:
Jing Dong, Christopher Staffi Buradagunta, Tao Zhang, Stephen Spellman, Yung-Tsi Bolon, Amy E. DeZern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Corey Cutler, Chao Cheng, Raul Urrutia, Paul Auer, Wael Saber
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Despite mitochondrial DNA (mtDNA) mutations are common events in cancer, their global frequency and clinical impact have not been comprehensively characterized in patients with myelodysplastic neoplasia (also known as myelodysplastic syndrom
Externí odkaz:
https://doaj.org/article/895c2192249f43b6861d6c677d997fa6
Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities
Autor:
Timothy S. Olson, Benjamin F. Frost, Jamie L. Duke, Marian Dribus, Hongbo M. Xie, Zachary D. Prudowsky, Elissa Furutani, Jonas Gudera, Yash B. Shah, Deborah Ferriola, Amalia Dinou, Ioanna Pagkrati, Soyoung Kim, Yixi Xu, Meilun He, Shannon Zheng, Sally Nijim, Ping Lin, Chong Xu, Taizo A. Nakano, Joseph H. Oved, Beatriz M. Carreno, Yung-Tsi Bolon, Shahinaz M. Gadalla, Steven G.E. Marsh, Sophie Paczesny, Stephanie J. Lee, Dimitrios S. Monos, Akiko Shimamura, Alison A. Bertuch, Loren Gragert, Stephen R. Spellman, Daria V. Babushok
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Acquired aplastic anemia (AA) is caused by autoreactive T cell–mediated destruction of early hematopoietic cells. Somatic loss of human leukocyte antigen (HLA) class I alleles was identified as a mechanism of immune escape in surviving hematopoieti
Externí odkaz:
https://doaj.org/article/d1c7bc07cfdf4986bc137dedb34e3f11
Autor:
Yuxin Yin, James H Lan, David Nguyen, Nicole Valenzuela, Ping Takemura, Yung-Tsi Bolon, Brianna Springer, Katsuyuki Saito, Ying Zheng, Tim Hague, Agnes Pasztor, Gyorgy Horvath, Krisztina Rigo, Elaine F Reed, Qiuheng Zhang
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165810 (2016)
Unambiguous HLA typing is important in hematopoietic stem cell transplantation (HSCT), HLA disease association studies, and solid organ transplantation. However, current molecular typing methods only interrogate the antigen recognition site (ARS) of
Externí odkaz:
https://doaj.org/article/93b13782bd134bffa4528fe1a03a5bcd
Publikováno v:
The Plant Genome, Vol 7, Iss 1 (2014)
The complex network of regulatory factors and interactions involved in transcriptional regulation within the seed is not well understood. To evaluate gene expression regulation in the immature seed, we utilized a genetical genomics approach on a soyb
Externí odkaz:
https://doaj.org/article/6afa2a10b96d4590befbf782789808fa
Autor:
Pietro Crivello, Esteban Arrieta-Bolaños, Meilun He, Tao Wang, Stephanie Fingerson, Shahinaz M. Gadalla, Sophie Paczesny, Steven G.E. Marsh, Stephanie J. Lee, Stephen R. Spellman, Yung-Tsi Bolon, Katharina Fleischhauer
Publikováno v:
Journal of Clinical Oncology. 41:2416-2427
PURPOSE Immunopeptidome divergence between mismatched HLA-DP is a determinant of T-cell alloreactivity and clinical tolerability after fully HLA-A, -B, -C, -DRB1, -DQB1 matched unrelated donor hematopoietic cell transplantation (UD-HCT). Here, we tes
Publikováno v:
Blood Advances.
HLA-DP is a classic transplantation antigen mediating alloreactivity through T-cell epitope (TCE) diversity and expression level. A current challenge is integrating these functional features into the prospective selection of candidate unrelated donor