Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yung-Shyeng Tsao"'
Autor:
Nicholas Murgolo, Zhimei Du, Robin S Ehrick, Jason D. Hughes, Guanghua Benson Li, Nihal Tugcu, Richard C. Stevens, Eric J Wallenstein, Jia Zhao, Jorge Quiroz, Matthew Manahan, Ren Liu, Yung-Shyeng Tsao, David Pollard, Jennifer M. Pollard, Michael C Nelson
Publikováno v:
Biotechnology progressREFERENCES. 38(1)
In recent years, assurance of clonality of the production cell line has been emphasized by health authorities during review of regulatory submissions. When insufficient assurance of clonality is provided, augmented control strategies may be required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad30f0dcf2ecf8f441813bca0f6ba820
https://pubmed.ncbi.nlm.nih.gov/34586757
https://pubmed.ncbi.nlm.nih.gov/34586757
Autor:
null Guanghua Benson Li, null Jennifer Pollard, null Ren Liu, null Richard C. Stevens, null Jorge Quiroz, null Michael C. Nelson, null Matthew Manahan, null Nicholas Murgolo, null Robin S. Ehrick, null Eric J. Wallenstein, null Jason Hughes, null Yung‐shyeng Tsao, null Jia Zhao, null Zhimei Du, null Nihal Tugcu, null David Pollard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332b821dd7adfa6023cfbd26752ab65a
https://doi.org/10.1002/btpr.3215/v2/response1
https://doi.org/10.1002/btpr.3215/v2/response1
Autor:
Jorge Quiroz, Yung-Shyeng Tsao
Publikováno v:
Biotechnology Progress. 32:1061-1068
Assurance of monoclonality of recombinant cell lines is a critical issue to gain regulatory approval in biological license application (BLA). Some of the requirements of regulatory agencies are the use of proper documentations and appropriate statist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de89c9bd8d137cc84f70c6b8c6d37e58
https://doi.org/10.1002/btpr.2290
https://doi.org/10.1002/btpr.2290
Autor:
Bernard Loo, Wei Shou Hu, Anne Kantardjieff, Nitya M. Jacob, Zhong Liu, Nandita Vishwanathan, Sze Wai Ng, Yung Shyeng Tsao, Huong Le
Publikováno v:
Biotechnology and Bioengineering. 111:518-528
Dihydrofolate reductase (DHFR) system is used to amplify the product gene to multiple copies in Chinese Hamster Ovary (CHO) cells for generating cell lines which produce the recombinant protein at high levels. The physiological changes accompanying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6997111f71202ee8bddbb6720c94e2a
https://doi.org/10.1002/bit.25117
https://doi.org/10.1002/bit.25117
Autor:
Zhong Liu, Shuangping Shi, Deba P. Saha, Paula D. Ravnikar, Russ Condon, Liang Deng, Yung-Shyeng Tsao, Lien Do, Finn Hung, Benson Li, Ankit A. Merchant
Publikováno v:
Biotechnology Journal. 5:393-401
The productivity of stably transfected cell lines is of critical importance for the manufacturing of therapeutic proteins. Various methods have been successfully implemented to increase the production output of mammalian cell cultures. Increasing evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b6e05b79e308b00e0f02b197a23607
https://doi.org/10.1002/biot.200900192
https://doi.org/10.1002/biot.200900192
Publikováno v:
Cytotechnology. 37:189-198
Human Embryonic Kidney 293 (HEK293) cells were adapted into a serum-free suspension medium through steps of gradual serum weaning for the production of adenoviral (AdV) gene therapy vectors. The presence of sodium heparin in the medium formulation re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9161b119c4b24e0529060891f68dbe0
https://doi.org/10.1023/a:1020555310558
https://doi.org/10.1023/a:1020555310558
Publikováno v:
Biotechnology Progress. 16:809-814
A method has been developed to monitor the cell growth of aggregated human embryonic kidney 293 (HEK293) suspension cultures by measuring cumulative particle volume and the particle size distribution. This method employs a particle size analyzer that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42972005edc23e705f2bc773b28b0487
https://doi.org/10.1021/bp000088k
https://doi.org/10.1021/bp000088k
Autor:
Nandita, Vishwanathan, Huong, Le, Nitya M, Jacob, Yung-Shyeng, Tsao, Sze-Wai, Ng, Bernard, Loo, Zhong, Liu, Anne, Kantardjieff, Wei-Shou, Hu
Publikováno v:
Biotechnology and bioengineering. 111(3)
Dihydrofolate reductase (DHFR) system is used to amplify the product gene to multiple copies in Chinese Hamster Ovary (CHO) cells for generating cell lines which produce the recombinant protein at high levels. The physiological changes accompanying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85b3d958c255a7ac8a21139da476a28d
https://pubmed.ncbi.nlm.nih.gov/24108600
https://pubmed.ncbi.nlm.nih.gov/24108600
Publikováno v:
Proceedings of the 14th Asia Pacific Confederation of Chemical Engineering Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab86f8b2cd6cc71b7096820f5e38ff6
https://doi.org/10.3850/978-981-07-1445-1_818
https://doi.org/10.3850/978-981-07-1445-1_818
Autor:
Liang Deng, Zhong Liu, Yung-Shyeng Tsao, Jason Saunders, Shuangping Shi, Russ G.G. Condon, Finn Hung
Publikováno v:
Journal of visualized experiments : JoVE. (55)
The fast-growing biopharmaceutical industry demands speedy development of highly efficient and reliable production systems to meet the increasing requirement for drug supplies. The generation of production cell lines has traditionally involved manual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2625cd5e94207488b277635fe893dbe6
https://pubmed.ncbi.nlm.nih.gov/21968840
https://pubmed.ncbi.nlm.nih.gov/21968840