Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yung Nan Liu"'
Publikováno v:
Biochemistry. 60:537-546
Oxetanocin-A is an antitumor, antiviral, and antibacterial nucleoside. It is biosynthesized via the oxidative ring contraction of a purine nucleoside co-opted from primary metabolism. This reaction is catalyzed by a B12-dependent radical S-adenosyl-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f69fdac369173ae0e6375125cc0a03
https://doi.org/10.1021/acs.biochem.0c00915
https://doi.org/10.1021/acs.biochem.0c00915
Publikováno v:
Journal of the American Chemical Society. 139:16084-16087
Many cobalamin (Cbl)-dependent radical S-adenosyl-L-methionine (SAM) methyltransferases have been identified through sequence alignment and/or genetic analysis; however, few have been studied in vitro. GenK is one such enzyme that catalyzes methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b29ec1a9b39447b9c2f41c4fa15434
https://doi.org/10.1021/jacs.7b09890
https://doi.org/10.1021/jacs.7b09890
Autor:
David H. Russell, Yung Nan Liu, Namho Kim, John W. Patrick, Hung-wen Liu, William K. Russell, Byung Sun Jeon, Geng-Min Lin, Sei Hyun Choi, Mark W. Ruszczycky, Shao-An Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 114:10408-10413
The Diels–Alder reaction is one of the most common methods to chemically synthesize a six-membered carbocycle. While it has long been speculated that the cyclohexene moiety found in many secondary metabolites is also introduced via similar chemistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fcfff7895d6351b54ed4c8255a10a8
https://doi.org/10.1073/pnas.1710496114
https://doi.org/10.1073/pnas.1710496114
Hyoscyamine 6β-hydroxylase (H6H) is an α-ketoglutarate dependent mononuclear nonheme iron enzyme that catalyzes C6-hydroxylation of hyoscyamine and oxidative cyclization of the resulting product to give the oxirane natural product scopolamine. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206bb22b7755d0bdcc65c5de5b9c6408
https://europepmc.org/articles/PMC6488034/
https://europepmc.org/articles/PMC6488034/
Autor:
Jake LeVieux, Reid M. McCarty, Steven O. Mansoorabadi, Yung Nan Liu, Yasushi Ogasawara, Hak Joong Kim, Hung-wen Liu
Publikováno v:
Journal of the American Chemical Society. 135:8093-8096
The existence of cobalamin (Cbl)-dependent enzymes that are members of the radical S-adenosyl-l-methionine (SAM) superfamily was previously predicted on the basis of bioinformatic analysis. A number of these are Cbl-dependent methyltransferases, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f61af5a1ec3f49baf164fc3f018f5f
https://doi.org/10.1021/ja312641f
https://doi.org/10.1021/ja312641f
Publikováno v:
Journal of the American Chemical Society. 134:13946-13949
UDP-D-apiose/UDP-D-xylose synthase (AXS) catalyzes the conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose. An acetyl-protected phosphonate analogue of UDP-D-apiose was synthesized and used in an in situ HPLC assay to demonstrate for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f9bd0ec1884d4b60b69bc2a93eee06
https://doi.org/10.1021/ja305322x
https://doi.org/10.1021/ja305322x
Publikováno v:
Nature. 473:109-112
The Diels-Alder reaction is a [4+2] cycloaddition reaction in which a cyclohexene ring is formed between a 1,3-diene and an electron-deficient alkene via a single pericyclic transition state. This reaction has been proposed as a key transformation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f120c0289c6e93e6fd93efa43f9d112
https://doi.org/10.1038/nature09981
https://doi.org/10.1038/nature09981
Autor:
Adrian T. Keatinge-Clay, Yung-Nan Liu, Hung-wen Liu, Drew T. Wagner, Christopher D. Fage, Eta A. Isiorho
Publikováno v:
Nature chemical biology
In the biosynthetic pathway of the spinosyn insecticides, the tailoring enzyme SpnF performs a [4+2]-cycloaddition on a 22-membered macrolactone to forge an embedded cyclohexene ring. To learn more about this reaction, which could potentially proceed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56d3af175c3832d5f020bbb1320e8d4
https://pubmed.ncbi.nlm.nih.gov/25730549
https://pubmed.ncbi.nlm.nih.gov/25730549
Publikováno v:
Journal of the American Chemical Society; 6/20/2018, Vol. 140 Issue 24, p7433-7436, 4p
Autor:
Yung-Nan Liu, 劉勇男
96
Curcumin, which is a natural yellow pigment. Product isolated from turmeric (Curcuma longa Linn.), has antioxidation, anti-inflammation, hepatoprotection activities. Pancreatic exocrine cell line AR42J can be transdifferentiated to hepatocyte
Curcumin, which is a natural yellow pigment. Product isolated from turmeric (Curcuma longa Linn.), has antioxidation, anti-inflammation, hepatoprotection activities. Pancreatic exocrine cell line AR42J can be transdifferentiated to hepatocyte
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/36131187229940946941