Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Yung Hua Wang"'
Autor:
Ning Zhao, Conner Bardine, André Luiz Lourenço, Yung-hua Wang, Yangjie Huang, Simon J. Cleary, David M. Wilson, David Y. Oh, Lawrence Fong, Mark R. Looney, Michael J. Evans, Charles S. Craik
Publikováno v:
ACS Central Science, Vol 7, Iss 10, Pp 1638-1649 (2021)
Externí odkaz:
https://doaj.org/article/855612b3a40e4f52a10ffc43856da1af
Autor:
Shubhangi Agarwal, Emilie Decavel-Bueff, Yung-Hua Wang, Hecong Qin, Romelyn Delos Santos, Michael J. Evans, Renuka Sriram
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tuberous sclerosis complex (TSC) is an inherited genetic disorder characterized by mutations in TSC1 or TSC2 class of tumor suppressers which impact several organs including the kidney. The renal manifestations are usually in the form of angiomyolipo
Externí odkaz:
https://doaj.org/article/b75e4148fb194f999cc6131b6ec6cafc
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers
Autor:
Shion A. Lim, Jie Zhou, Alexander J. Martinko, Yung-Hua Wang, Ekaterina V. Filippova, Veronica Steri, Donghui Wang, Soumya G. Remesh, Jia Liu, Byron Hann, Anthony A. Kossiakoff, Michael J. Evans, Kevin K. Leung, James A. Wells
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 4 (2022)
Extracellular proteolysis is frequently dysregulated in disease and can generate proteoforms with unique neoepitopes not found in healthy tissue. Here, we demonstrate that Abs that selectively recognize a proteolytic neoepitope on CUB domain containi
Externí odkaz:
https://doaj.org/article/185e24f5d7a047799beb370607485344
Autor:
Ryan K. Muir, Ning Zhao, Junnian Wei, Yung-hua Wang, Anna Moroz, Yangjie Huang, Ying-Chu Chen, Renuka Sriram, John Kurhanewicz, Davide Ruggero, Adam R. Renslo, Michael J. Evans
Publikováno v:
ACS Central Science, Vol 5, Iss 4, Pp 727-736 (2019)
Externí odkaz:
https://doaj.org/article/8a1f8dc0392b4f1ca4cc2864af7b7b4e
Autor:
Jiang He, Robert R. Flavell, Bin Liu, Youngho Seo, Michael J. Evans, Rahul Aggarwal, Felix Y. Feng, Jonathan Chou, Emily A. Egusa, Renuka Sriram, Robert Dreicer, Daniel Gioeli, Sui Shen, Fujun Qin, Yangjie Huang, Yung-hua Wang, Ning Zhao, Tony L. Huynh, Mayuri Jayaraman, Walter Zhao, Denis R. Beckford-Vera, Yang Su, Jun Hua, Jun Li, Sinan Wang
Supplemental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d7d6de383c8b0ea70d0c1ea75bf417
https://doi.org/10.1158/1078-0432.22478267
https://doi.org/10.1158/1078-0432.22478267
Autor:
Michael J. Evans, Rahul Aggarwal, James A. Wells, Jonathan Chou, Eric J. Small, Felix Y. Feng, Youngho Seo, Emily Chan, Renuka Sriram, Adam Foye, Li Zhang, Jun Zhu, Emily A. Egusa, Kevin K. Leung, Shion A. Lim, Jie Zhou, Hyunjung Kim, Nima Hooshdaran, Sasank Sakhamuri, Yung-Hua Wang, Kai Trepka, Shalini Chopra, Ning Zhao
Supplementary Table from CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7202861d7ba2f0a879bfc4b29eba348
https://doi.org/10.1158/1078-0432.22486157.v1
https://doi.org/10.1158/1078-0432.22486157.v1
Autor:
Michael J. Evans, James A. Wells, Kimberly S. Kirkwood, Eric A. Collisson, Kevin K. Leung, Sean Carlin, Youngho Seo, Lydia H. Zhang, Shion A. Lim, Jie Zhuo, Alexander J. Martinko, Zhuo Chen, Yangjie Huang, Ning Zhao, Junnian Wei, Jeremy M. Sharib, Yung-Hua Wang, Anna Moroz
Purpose:The recent emergence of radioligand therapies for cancer treatment has increased enthusiasm for developing new theranostic strategies coupling both imaging and cytotoxicity in the same entity. In this study, we evaluated whether CUB domain co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a058b3064dd4e9ecfa3f980c0898668c
https://doi.org/10.1158/1078-0432.c.6528857
https://doi.org/10.1158/1078-0432.c.6528857
Autor:
Jiang He, Robert R. Flavell, Bin Liu, Youngho Seo, Michael J. Evans, Rahul Aggarwal, Felix Y. Feng, Jonathan Chou, Emily A. Egusa, Renuka Sriram, Robert Dreicer, Daniel Gioeli, Sui Shen, Fujun Qin, Yangjie Huang, Yung-hua Wang, Ning Zhao, Tony L. Huynh, Mayuri Jayaraman, Walter Zhao, Denis R. Beckford-Vera, Yang Su, Jun Hua, Jun Li, Sinan Wang
Purpose:We recently identified CD46 as a novel therapeutic target in prostate cancer. In this study, we developed a CD46-targeted PET radiopharmaceutical, [89Zr]DFO-YS5, and evaluated its performance for immunoPET imaging in murine prostate cancer mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085718a503055dc4a4e8553c7641a654
https://doi.org/10.1158/1078-0432.c.6529904.v1
https://doi.org/10.1158/1078-0432.c.6529904.v1
Autor:
Michael J. Evans, Rahul Aggarwal, James A. Wells, Jonathan Chou, Eric J. Small, Felix Y. Feng, Youngho Seo, Emily Chan, Renuka Sriram, Adam Foye, Li Zhang, Jun Zhu, Emily A. Egusa, Kevin K. Leung, Shion A. Lim, Jie Zhou, Hyunjung Kim, Nima Hooshdaran, Sasank Sakhamuri, Yung-Hua Wang, Kai Trepka, Shalini Chopra, Ning Zhao
Supplementary Figure from CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c57f6fa7feebd91bb46f1e618ae91cc
https://doi.org/10.1158/1078-0432.22486163.v1
https://doi.org/10.1158/1078-0432.22486163.v1
Autor:
Michael J. Evans, Rahul Aggarwal, James A. Wells, Jonathan Chou, Eric J. Small, Felix Y. Feng, Youngho Seo, Emily Chan, Renuka Sriram, Adam Foye, Li Zhang, Jun Zhu, Emily A. Egusa, Kevin K. Leung, Shion A. Lim, Jie Zhou, Hyunjung Kim, Nima Hooshdaran, Sasank Sakhamuri, Yung-Hua Wang, Kai Trepka, Shalini Chopra, Ning Zhao
Purpose:With the improvement in overall survival with 177Lu-PSMA 617, radioligand therapy (RLT) is now a viable option for patients with metastatic castration-resistant prostate cancer (mCRPC). However, responses are variable, in part due to low PSMA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b082113f876c3ce1134300d647cec0f
https://doi.org/10.1158/1078-0432.c.6532265.v1
https://doi.org/10.1158/1078-0432.c.6532265.v1