Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Yunfei LIAO"'
Publikováno v:
Stem Cell Research, Vol 78, Iss , Pp 103451- (2024)
Hereditary fructose intolerance (HFI) is an autosomal recessive metabolic disease associated with a mutation in the aldolase B gene on chromosome 9q31. In this study, we generated a human-induced pluripotent stem cell (hiPSC) line, FDCHi015-A, from p
Externí odkaz:
https://doaj.org/article/fa8adbb01d1b43eea5c6651157e13d22
Autor:
Yinliang Zhang, Chunyuan Du, Wei Wang, Wei Qiao, Yuhui Li, Yujie Zhang, Sufang Sheng, Xuenan Zhou, Lei Zhang, Heng Fan, Ying Yu, Yong Chen, Yunfei Liao, Shihong Chen, Yongsheng Chang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The mechanisms underlying glucocorticoid (GC)-induced obesity are poorly understood. Macrophages are the primary targets by which GCs exert pharmacological effects and perform critical functions in adipose tissue homeostasis. Here, we show t
Externí odkaz:
https://doaj.org/article/55509ae258d14b1caa4e019c7d861089
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Background Asthma is widely recognized as an inflammatory disorder. In the context of this inflammatory microenvironment, the involvement of hypoxia and its impact on related pathways have drawn considerable attention. However, the exact rol
Externí odkaz:
https://doaj.org/article/e7767f750de64cbebee68a0a3cdb9bcb
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103369- (2024)
Neurodevelopmental disorder with or without autistic features and/or structural brain abnormalities (NEDASB) is a rare autosomal dominant disorder caused by a heterozygous mutation in the NOVA2 gene on chromosome 19q13. Here, we describe the generati
Externí odkaz:
https://doaj.org/article/e7492c268c724264b4d0313198dbb424
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Myocardial ischemia-reperfusion injury (MIRI) is one of the main reasons for poor prognosis in patients with ischemic cardiomyopathy (ICM). To date, the mechanism remains unknown. As members of the silent information regulator 2 (
Externí odkaz:
https://doaj.org/article/1b4b640f0d574718b167163cc6599526
Autor:
Yi Zhang, Liwei Chen, Ye Xuan, Lina Zhang, Wen Tian, Yangyang Zhu, Jinghui Wang, Xinyu Wang, Jin Qiu, Jian Yu, Mengyang Tang, Zhen He, Hong Zhang, Si Chen, Yun Shen, Siyi Wang, Rong Zhang, Lingyan Xu, Xinran Ma, Yunfei Liao, Cheng Hu
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113900- (2024)
Summary: Iron overload is closely associated with metabolic dysfunction. However, the role of iron in the hypothalamus remains unclear. Here, we find that hypothalamic iron levels are increased, particularly in agouti-related peptide (AgRP)-expressin
Externí odkaz:
https://doaj.org/article/113970000ab24969ac0cd5665c0aa046
Autor:
Yunfei Liao, Slim Sassi, Stefan Halvorsen, Yong Feng, Jacson Shen, Yan Gao, Gregory Cote, Edwin Choy, David Harmon, Henry Mankin, Francis Hornicek, Zhenfeng Duan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/bfd2fe52e03f42fc801106da7e98ba2b
Autor:
Zaili Luo, Dazhuan Xin, Yunfei Liao, Kalen Berry, Sean Ogurek, Feng Zhang, Liguo Zhang, Chuntao Zhao, Rohit Rao, Xinran Dong, Hao Li, Jianzhong Yu, Yifeng Lin, Guoying Huang, Lingli Xu, Mei Xin, Ryuichi Nishinakamura, Jiyang Yu, Marcel Kool, Stefan M. Pfister, Martine F. Roussel, Wenhao Zhou, William A. Weiss, Paul Andreassen, Q. Richard Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Group 3 medulloblastomas (MBs) have the worst prognosis amongst the subtypes of MBs and are associated with MYC amplifications. Here the authors identify that mutations in CTDNEP1 cause MYC activation, amplification, and genomic instability in this s
Externí odkaz:
https://doaj.org/article/050dee8c5d78498a83433567aac6e737
Autor:
Yunfei Liao, Zaili Luo, Yifeng Lin, Huiyao Chen, Tong Chen, Lingli Xu, Sean Orgurek, Kalen Berry, Monika Dzieciatkowska, Julie A. Reisz, Angelo D’Alessandro, Wenhao Zhou, Q. Richard Lu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-14 (2022)
Abstract Glioblastoma (GBM) is the most common and aggressive primary brain tumor, but the mechanisms underlying tumor growth and progression remain unclear. The protein arginine methyltransferases (PRMTs) regulate a variety of biological processes,
Externí odkaz:
https://doaj.org/article/e8adcceec4f64f27aaa33c9a1edb57d6
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103118- (2023)
A human induced pluripotent stem cell line (iPSC), FDCHi010-A, was derived from the peripheral blood of a 3-year-old patient with the c.2062C > T (p.R688*) mutation in the AHDC1 gene. The established cell line displayed a typical human embryonic stem
Externí odkaz:
https://doaj.org/article/cb7e88ea5ca64a15b4bc59e233fe9358