Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model

Autor: Falk Saupe, Anja Schwenzer, Yundan Jia, Isabelle Gasser, Caroline Spenlé, Benoit Langlois, Martial Kammerer, Olivier Lefebvre, Ruslan Hlushchuk, Tristan Rupp, Marija Marko, Michael van der Heyden, Gérard Cremel, Christiane Arnold, Annick Klein, Patricia Simon-Assmann, Valentin Djonov, Agnès Neuville-Méchine, Irene Esposito, Julia Slotta-Huspenina, Klaus-Peter Janssen, Olivier de Wever, Gerhard Christofori, Thomas Hussenet, Gertraud Orend

Publikováno v: Cell Reports, Vol 5, Iss 2, Pp 482-492 (2013)

The extracellular matrix molecule tenascin-C (TNC) is a major component of the cancer-specific matrix, and high TNC expression is linked to poor prognosis in several cancers. To provide a comprehensive understanding of TNC’s functions in cancer, we

Externí odkaz: https://doaj.org/article/eef0c323ad994db48291a3ed7448ad8f

Efficient generation of mouse ESCs-like pig induced pluripotent stem cells

Autor: Juan Wang, Qi Zhou, Yundan Jia, Jianyu Wang, Jie Hao, Lei Liu, Bingteng Xie, Tang Hai, Binghua Xue, Qingran Kong, Zhonghua Liu, Shichao Liu, Yilong He, Qi Gu, Jialu Sun, Jinyu Li, Liu Wang, Chunjing Feng

Publikováno v: Protein & Cell

Dear Editor, Porcine induced pluripotency stem cells (piPSCs) are promised in basic research, animal husbandry and regenerative medicine. However, the efficiency of the piPSCs induction has been low and the generated piPSCs varied in cell morphology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70235b55badf1ebe39e6062b0bd3b7fd
https://doi.org/10.1007/s13238-014-0043-2

Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model

Autor: Christiane Arnold, Marija Marko, Gerhard Christofori, Ruslan Hlushchuk, Tristan Rupp, Olivier De Wever, Martial Kammerer, Isabelle Gasser, Falk Saupe, Michael van der Heyden, Gertraud Orend, Benoit Langlois, Klaus-Peter Janssen, Thomas Hussenet, Olivier Lefebvre, Gérard Crémel, Annick Klein, Caroline Spenlé, Agnès Neuville-Méchine, Irene Esposito, Patricia Simon-Assmann, Valentin Djonov, Julia Slotta-Huspenina, Yundan Jia, Anja Schwenzer

Publikováno v: CELL REPORTS
Cell Reports, Vol 5, Iss 2, Pp 482-492 (2013)
Saupe, Falk; Schwenzer, Anja; Jia, Yundan; Gasser, Isabelle; Spenlé, Caroline; Langlois, Benoit; Kammerer, Martial; Lefebvre, Olivier; Hlushchuk, Ruslan; Rupp, Tristan; Marko, Marija; van der Heyden, Michael; Cremel, Gérard; Arnold, Christiane; Klein, Annick; Simon-Assmann, Patricia; Djonov, Valentin; Neuville-Méchine, Agnès; Esposito, Irene; Slotta-Huspenina, Julia; ... (2013). Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model. Cell reports, 5(2), pp. 482-492. Cell Press 10.1016/j.celrep.2013.09.014
Cell reports

SummaryThe extracellular matrix molecule tenascin-C (TNC) is a major component of the cancer-specific matrix, and high TNC expression is linked to poor prognosis in several cancers. To provide a comprehensive understanding of TNC’s functions in can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38b8d5c1b8cab9b0abc5a64668c4c27

Alterations in Wnt-β -catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression

Autor: John P. Lydon, Claudia Heijmans-Antonissen, Riccardo Fodde, Curt W. Burger, Francesco J. DeMayo, Patricia C. Ewing, Yundan Jia, Leen J. Blok, Yongyi Wang, Marten van der Zee, Patrick Franken

Publikováno v: The Journal of Pathology. 230:48-58

Endometrioid endometrial cancer arises through a gradual series of histological changes, each accompanied by specific alterations in gene expression and activity. Activation of the Wnt-β-catenin pathway and loss of PTEN activity are frequently obser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19acfe5fdc5822a2b76f005e7a8d6a50
https://doi.org/10.1002/path.4160

A novel variant of Oct3/4 gene in mouse embryonic stem cells

Autor: Lei Liu, Yundan Jia, Qi Zhou, Chang-long Guo, Liu Wang, Xiaoyang Zhao

Publikováno v: Stem Cell Research. 9(2):69-76

OCT4 is a highly conserved gene and plays an important role during early embryonic development and differentiation. Similar to human OCT4, mouse Oct4 gene generates variants. Oct4A is a master regulator of self-renewal in pluripotent stem cells. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c656dfd8478f8a261917342999e50687