Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Yuncheng Man"'
Autor:
Utku Goreke, Ayesha Gonzales, Brandon Shipley, Madeleine Tincher, Oshin Sharma, William J. Wulftange, Yuncheng Man, Ran An, Michael Hinczewski, Umut A. Gurkan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Imaging and characterizing the dynamics of cellular adhesion in blood samples is of fundamental importance in understanding biological function. In vitro microscopy methods are widely used for this task but typically require diluting the blo
Externí odkaz:
https://doaj.org/article/f43a33dd101845b5a7e8f19416c7e5af
Autor:
Queeny Dasgupta, Amanda Jiang, Amy M. Wen, Robert J. Mannix, Yuncheng Man, Sean Hall, Emilia Javorsky, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Acute exposure to high-dose gamma radiation due to radiological disasters or cancer radiotherapy can result in radiation-induced lung injury (RILI), characterized by acute pneumonitis and subsequent lung fibrosis. A microfluidic organ-on-a-c
Externí odkaz:
https://doaj.org/article/6ae3452b30aa4654a34caaf5a5e810af
Autor:
Ran An, Yuning Huang, Anne Rocheleau, Alireza Avanaki, Priyaleela Thota, Qiaochu Zhang, Yuncheng Man, Zoe Sekyonda, Catherine I. Segbefia, Yvonne Dei-Adomakoh, Enoch Mensah, Kwaku Ohene-Frempong, Isaac Odame, Amma Owusu-Ansah, Umut A. Gurkan
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e11778- (2022)
Hemoglobin (Hb) disorders affect nearly 7% of the world’s population. Globally, around 400,000 babies are born annually with sickle cell disease (SCD), primarily in sub-Saharan Africa where morbidity and mortality rates are high. Screening, early d
Externí odkaz:
https://doaj.org/article/3afc83a2f7714440a6ae0b2eeb33d867
Autor:
Yuncheng Man, Ran An, Karamoja Monchamp, Zoe Sekyonda, Erdem Kucukal, Chiara Federici, William J. Wulftange, Utku Goreke, Allison Bode, Vivien A. Sheehan, Umut A. Gurkan
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Red blood cell (RBC) deformability is a valuable hemorheological biomarker that can be used to assess the clinical status and response to therapy of individuals with sickle cell disease (SCD). RBC deformability has been measured by ektacytometry for
Externí odkaz:
https://doaj.org/article/addde170f9b44f8283e6b69fa8a481c4
Autor:
Hangying She, Yuncheng Man
Publikováno v:
Healthcare, Vol 10, Iss 2, p 356 (2022)
This study aims to analyze the concept of anticipatory burden in adult-child caregivers. A systematic literature review was performed using four databases, Pubmed, CINAHL, PsycINFO and Medline, with the keywords of “anticipatory burden” and “an
Externí odkaz:
https://doaj.org/article/cce747bde5fe432d8c74ff9fdd44c699
Autor:
Shenbo Xu, Yuncheng Man, Wenkun Dou, Shu Yang, Linchuan Zhao, Haoyang He, Yujing Hong, Yumeng Zheng
Publikováno v:
Sensing and Bio-Sensing Research, Vol 7, Iss , Pp 25-30 (2016)
Electrochemiluminescence (ECL) detection is one of the most prevailing electrochromism approaches to test biotin and chemicals. As thorny ECL signals by impurities are devastative in judging the right substance and its concentration precisely, it is
Externí odkaz:
https://doaj.org/article/e4df64e8877c4d95a8c1c8bf3bd50037
Autor:
Utku Goreke, Erdem Kucukal, Fang Wang, Ran An, Nicole Arnold, Erina Quinn, Charlotte Yuan, Allison Bode, Ailis Hill, Yuncheng Man, Bryan C. Hambley, Robert Schilz, Mahazarin Ginwalla, Jane A. Little, Umut A. Gurkan
Publikováno v:
Blood Advances. 7:2094-2104
Abnormal erythrocyte adhesion owing to polymerization of sickle hemoglobin is central to the pathophysiology of sickle cell disease (SCD). Mature erythrocytes constitute >80% of all erythrocytes in SCD; however, the relative contributions of erythroc
Autor:
Ran An, Yuncheng Man, Kevin Cheng, Tianyi Zhang, Chunsheng Chen, Fang Wang, Fuad Abdulla, Erdem Kucukal, William J. Wulftange, Utku Goreke, Allison Bode, Lalitha V. Nayak, Gregory M. Vercellotti, John D. Belcher, Jane A. Little, Umut A. Gurkan
Publikováno v:
British Journal of Haematology. 201:552-563
Endothelial activation and sickle red blood cell (RBC) adhesion are central to the pathogenesis of sickle cell disease (SCD). Quantitatively, RBC-derived extracellular vesicles (REVs) are more abundant from SS RBCs compared with healthy RBCs (AA RBCs
Autor:
Yuncheng Man, Douglas H. Wu, Ran An, Peiran Wei, Karamoja Monchamp, Utku Goreke, Zoe Sekyonda, William J. Wulftange, Chiara Federici, Allison Bode, Lalitha V. Nayak, Jane A. Little, Umut A. Gurkan
Publikováno v:
Sensors & Diagnostics. 2:457-467
A microfluidic assay integrated with capillary network-inspired microcapillary arrays and endothelial-associated protein functionalization enables concurrent assessment of red blood cell adhesion and microcapillary occlusion.
Autor:
Ran An, Yuncheng Man, Kevin Cheng, Tianyi Zhang, Chunsheng Chen, Erdem Kucukal, William Wulftange, Utku Goreke, Allison Bode, Lalitha Nayak, Gregory M. Vercellotti, John D Belcher, Jane Alison Little, Umut A. Gurkan
Publikováno v:
Blood. 140:8223-8225