Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuncheng Bei"'
Autor:
Luchen Sun, Nanfei Yang, Bing Chen, Yuncheng Bei, Zisheng Kang, Can Zhang, Nan Zhang, Peipei Xu, Wei Yang, Jia Wei, Jiangqiong Ke, Weijian Sun, Xiaokun Li, Pingping Shen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 3027-3042 (2023)
Currently the main treatment of acute myeloid leukemia (AML) is chemotherapy combining hematopoietic stem cell transplantation. However, the unbearable side effect of chemotherapy and the high risk of life-threatening infections and disease relapse f
Externí odkaz:
https://doaj.org/article/74a0d1e178e54159a8d09a795d333824
Autor:
Ruihan Xu, Qin Wang, Junmeng Zhu, Yuncheng Bei, Yanhong Chu, Zhichen Sun, Shiyao Du, Shujuan Zhou, Naiqing Ding, Fanyan Meng, Baorui Liu
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract T cell receptor‐engineered T (TCR‐T) cell therapy has demonstrated therapeutic effects in basic research and clinical trials for treating solid tumors. Due to the peptide‐dependent recognition and the human leukocyte antigen (HLA)‐re
Externí odkaz:
https://doaj.org/article/8f35a83d63144ce2a913fb085e2edbeb
Autor:
Yuxin Shu, Nanfei Yang, Nan Cheng, Zhengyun Zou, Wenlong Zhang, Yuncheng Bei, Qian Shi, Menghao Qin, Wei-Guo Zhu, Pingping Shen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/495f2074ed164518aac864ec1da28f8c
Autor:
Yuncheng Bei, Nan Cheng, Ting Chen, Yuxin Shu, Ye Yang, Nanfei Yang, Xinyu Zhou, Baorui Liu, Jia Wei, Qin Liu, Wei Zheng, Wenlong Zhang, Huifang Su, Wei‐Guo Zhu, Jianguo Ji, Pingping Shen
Publikováno v:
Advanced Science, Vol 7, Iss 22, Pp n/a-n/a (2020)
Abstract Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, in which the higher frequency of cancer stem cells (CSCs) correlates with the poor clinical outcome. An aberrant activation of CDK5 is found to associate
Externí odkaz:
https://doaj.org/article/246c50f459d94f8ab89eb2dbed23ab22
Autor:
Yuncheng Bei, Jian He, Xuhui Dong, Yuxin Wang, Sijie Wang, Wan Guo, Chengjie Cai, Zhiye Xu, Jia Wei, Baorui Liu, Nan Zhang, Pingping Shen
Publikováno v:
Cancer Research.
Intrahepatic cholangiocarcinoma (ICC) is the second most frequent type of primary liver cancer. ICC is among the deadliest malignancies, highlighting that novel treatments are urgently needed. Studies have shown that CD44 variant isoforms, rather tha
Autor:
Sijie Wang, Yuncheng Bei, Qiang Tian, Jian He, Rui Wang, Qiuping Wang, Luchen Sun, Jiangqiong Ke, Congying Xie, Pingping Shen
Publikováno v:
Cell Proliferation. 56
ERWestern blotting, qPCR, flow cytometry and a series of cell experiments were performed to evaluate the phenotype of MCF-7/R cells. RNA sequencing, non-targeted metabolomics, shRNA knockdown and tumour cell-bearing mouse models were used to clarify
Autor:
Yuncheng Bei, Jian He, Xuhui Dong, Yuxin Wang, Wan Guo, Chengjie Cai, Zhiye Xu, Jia Wei, Baorui Liu, Pingping Shen
Publikováno v:
SSRN Electronic Journal.
Autor:
Weijie Zhang, Huifang Su, Qin Liu, Wei Zheng, Jie Shen, Yan Lu, Yuncheng Bei, Pingping Shen, Hanren Dai, Ling Liu, Wenlong Zhang
Publikováno v:
British Journal of Cancer
BackgroundThe extracellular matrix (ECM) is essential for malignant tumour progression, as it is a physical barrier to various kinds of anticancer therapies. Matrix metalloproteinase (MMPs) can degrade almost all ECM components, and macrophages are a
Autor:
Xuexia Bai, Yue Song, Lizhi Xu, Wenlong Zhang, Nanfei Yang, Nan Cheng, Weijie Zhang, Yuncheng Bei, Yuxin Shu, Pingping Shen
Publikováno v:
Biochemical Pharmacology. 183:114298
B7-H3 is an immune checkpoint molecule from the B7 superfamily. It has been widely studied in tumor immune evasion in certain types of cancer. In our preliminary study, we found that B7-H3 is specifically enriched in tumor-associated macrophages (TAM
Publikováno v:
Scientific Reports
Extracellular signal-regulated kinase (ERK) belongs to the mitogen-activated protein kinases (MAPK) superfamily. Aberrant upregulation and activation of ERK cascades may often lead to tumor cell development. However, how ERK is involved in tumor prog