Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Yunchao Su"'
Autor:
Jing Liu, Qi Sun, Qi Zhang, Fang Ye, Yuanmei Chen, Lijuan Tang, Die Liu, Yunchao Su, Haixiao Liang
Publikováno v:
BMJ Paediatrics Open, Vol 8, Iss 1 (2024)
Background Placental histological chorioamnionitis (HCA) is recognised as a significant risk factor for various adverse neonatal outcomes. This study aims to explore if the inflammatory protein levels in neonates were associated with HCA.Methods All
Externí odkaz:
https://doaj.org/article/143c7295c42b4dec8ea52f6cabef89f9
Autor:
Rahul S. Patil, McKenzie E. Maloney, Rudolf Lucas, David J. R. Fulton, Vijay Patel, Zsolt Bagi, Anita Kovacs-Kasa, Laszlo Kovacs, Yunchao Su, Alexander D. Verin
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 140 (2024)
A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and, as such, provides a semi-selective barrier between the blood and the interstitial space. Compromise of the lung EC barrier due to inflammatory or toxic events may result in
Externí odkaz:
https://doaj.org/article/13389f60a41a4945b12c9ded7ddd2c0f
Autor:
Rahul S. Patil, Anita Kovacs-Kasa, Boris A. Gorshkov, David J. R. Fulton, Yunchao Su, Robert K. Batori, Alexander D. Verin
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1638 (2023)
Vascular barrier dysfunction is characterized by increased permeability and inflammation of endothelial cells (ECs), which are prominent features of acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and sepsis, and a major complica
Externí odkaz:
https://doaj.org/article/ca6912e799864577b025471f55d1cc1f
Autor:
Robert K. Batori, Feng Chen, Zsuzsanna Bordan, Stephen Haigh, Yunchao Su, Alexander D. Verin, Scott A. Barman, David W. Stepp, Trinad Chakraborty, Rudolf Lucas, David J. R. Fulton
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pneumolysin (PLY) is a bacterial pore forming toxin and primary virulence factor of Streptococcus pneumonia, a major cause of pneumonia. PLY binds cholesterol-rich domains of the endothelial cell (EC) plasma membrane resulting in pore assembly and in
Externí odkaz:
https://doaj.org/article/a855244bd2ed44449d1488efd66170f2
Autor:
Jiean Xu, Lina Wang, Qiuhua Yang, Qian Ma, Yaqi Zhou, Yongfeng Cai, Xiaoxiao Mao, Qingen Da, Tammy Lu, Yunchao Su, Zsolt Bagi, Rudolf Lucas, Zhiping Liu, Mei Hong, Kunfu Ouyang, Yuqing Huo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Sepsis, a pathology resulting from excessive inflammatory response that leads to multiple organ failure, is a major cause of mortality in intensive care units. Macrophages play an important role in the pathophysiology of sepsis. Accumulating evidence
Externí odkaz:
https://doaj.org/article/9347e206786c4b018ec1c48bc2cc7e1d
Autor:
Chunman Li, Zhe Wei, Yi Fan, Wei Huang, Yunchao Su, Honglin Li, Zheng Dong, Mitsunori Fukuda, Mostafa Khater, Guangyu Wu
Publikováno v:
Cell Reports, Vol 21, Iss 4, Pp 1089-1101 (2017)
Summary: G-protein-coupled receptors (GPCRs) constitute the largest superfamily of cell-surface signaling proteins. However, mechanisms underlying their surface targeting and sorting are poorly understood. Here, we screen the Rab family of small GTPa
Externí odkaz:
https://doaj.org/article/af2bf02e8e53400f9188940999d120b3
Autor:
Xueyi Li, Yanfang Yu, Boris Gorshkov, Stephen Haigh, Zsuzsanna Bordan, Daniel Weintraub, Radu Daniel Rudic, Trinad Chakraborty, Scott A. Barman, Alexander D. Verin, Yunchao Su, Rudolf Lucas, David W. Stepp, Feng Chen, David J. R. Fulton
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Pneumonia is a leading cause of death in children and the elderly worldwide, accounting for 15% of all deaths of children under 5 years old. Streptococcus pneumoniae is a common and aggressive cause of pneumonia and can also contribute to meningitis
Externí odkaz:
https://doaj.org/article/f70a72936b734b8b8fcae30c5e3a0770
Autor:
Istvan Czikora, Abdel A. Alli, Supriya Sridhar, Michael A. Matthay, Helena Pillich, Martina Hudel, Besim Berisha, Boris Gorshkov, Maritza J. Romero, Joyce Gonzales, Guangyu Wu, Yuqing Huo, Yunchao Su, Alexander D. Verin, David Fulton, Trinad Chakraborty, Douglas C. Eaton, Rudolf Lucas
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
BackgroundStreptococcus pneumoniae is a major etiologic agent of bacterial pneumonia. Autolysis and antibiotic-mediated lysis of pneumococci induce release of the pore-forming toxin, pneumolysin (PLY), their major virulence factor, which is a promine
Externí odkaz:
https://doaj.org/article/e00463dfbf08482284ebe0f2bdc7fe4c
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129343 (2015)
Exposure of pulmonary artery endothelial cells (PAECs) to hyperoxia results in a compromise in endothelial monolayer integrity, an increase in caspase-3 activity, and nuclear translocation of apoptosis-inducing factor (AIF), a marker of caspase-indep
Externí odkaz:
https://doaj.org/article/241984b3d570445db7b2223df6a6c9f5
Autor:
Haroldo A Toque, Kenia P Nunes, Lin Yao, Zhimin Xu, Dmitry Kondrikov, Yunchao Su, R Clinton Webb, Ruth B Caldwell, R William Caldwell
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72277 (2013)
Elevated arginase (Arg) activity is reported to be involved in diabetes-induced vascular endothelial dysfunction. It can reduce L-arginine availability to nitric oxide (NO) synthase (NOS) and NO production. Akita mice, a genetic non-obese type 1 diab
Externí odkaz:
https://doaj.org/article/6d645224a93f4a4ba7edd4c00b6e35ae