Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yuncang Yuan"'
Autor:
Jiawei Fan, Ye Yu, Lanzhen Yan, Yuncang Yuan, Bin Sun, Dong Yang, Nan Liu, Jing Guo, Jie Zhang, Xudong Zhao
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-17 (2023)
Abstract Background The receptor tyrosine kinases TAM family (TYRO3, AXL, and MERTK) are highly expressed in multiple forms of cancer cells and tumor-associated macrophages and promote the development of cancers including pancreatic tumor. Targeting
Externí odkaz:
https://doaj.org/article/be10e2f9fee44cdfa858d3e232cc100a
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Glioblastoma (GBM) is recognized as among the most aggressive forms of brain tumor. Patients typically present with a five-year survival rate of less than 6% with traditional surgery and chemoradiotherapy, which calls for novel im
Externí odkaz:
https://doaj.org/article/8e3234b3d6d046d2918ac2e00b1158fb
Autor:
Yuncang Yuan, Jiawei Fan, Dandan Liang, Shijie Wang, Xu Luo, Yongjie Zhu, Nan Liu, Tingxiu Xiang, Xudong Zhao
Publikováno v:
Translational Oncology, Vol 39, Iss , Pp 101803- (2024)
Pancreatic cancer is a highly lethal solid malignancy with limited treatment options. Chimeric antigen receptor T (CAR-T) cell therapy has been successfully applied to treat hematological malignancies, but faces many challenges in solid tumors. One m
Externí odkaz:
https://doaj.org/article/e2f9a8d484ea494abecbc13aa4c2b892
Cell-Surface GRP78-Targeted Chimeric Antigen Receptor T Cells Eliminate Lung Cancer Tumor Xenografts
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 564 (2024)
Lung cancer is one of the most common and intractable malignancies. It is associated with low survival rates despite existing treatments, indicating that new and more effective therapies are urgently needed such as the chimeric antigen receptor-T (CA
Externí odkaz:
https://doaj.org/article/cf314e5576b840389a2097431f343411
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Acute myeloid leukemia (AML) is a serious, life-threatening hematological malignancy. The treatment outcome of relapsed or refractory AML patients remains dismal, and new treatment options are needed. Chimeric antigen receptor (CAR) T cells have been
Externí odkaz:
https://doaj.org/article/606560b47d634c98a63cc2cb1ec51418
Autor:
Ye Li, Yuncang Yuan, Fan Zhang, Aizhen Guo, Fuao Cao, Mengmeng Song, Yating Fu, Xiaowen Xu, Hao Shen, Shangyong Zheng, Yamin Pan, Wenjun Chang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
SHP2 mediates signaling from multiple receptor tyrosine kinases (RTKs) to extracellular signal-regulated kinase (ERK) and Ser and Thr kinase AKT, and its inhibitors offer an unprecedented opportunity for cancer treatment. Although the ERK signaling v
Externí odkaz:
https://doaj.org/article/5b77e158ef9f4631b187c840f6022ce3
Autor:
Tianqi Dong, Yuncang Yuan, Xudong Xiang, Shuping Sang, Hao Shen, Lei Wang, Chunyan Yang, Fangfang Li, Hongliang Li, Shangyong Zheng
Publikováno v:
PeerJ, Vol 8, p e10397 (2020)
Purpose Yes associated protein 1 (YAP1), which is a standout amongst the most essential effectors of the Hippo pathway, assumes a vital part in a few kinds of cancer. However, whether YAP1 is an oncogene in CRC (colorectal cancer) remains controversi
Externí odkaz:
https://doaj.org/article/153dec1c55894aa9abb7979079db589b
Autor:
Qian Li, Pengzhan Ran, Xiyu Zhang, Xiaopeng Guo, Yuncang Yuan, Tianqi Dong, Bei Zhu, Shangyong Zheng, Chunjie Xiao
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 3, Pp 987-1004 (2018)
Background/Aims: GCNT3 is a member of N-acetylglucosaminyltransferase family involved with mucin biosynthesis. GCNT3 aberrant expression is known to promote the progression of several human cancers. However, its role in tumorigenesis and the progress
Externí odkaz:
https://doaj.org/article/f89d5c1248f343b885a108635e0508d0
Publikováno v:
International Journal of Gynaecology and Obstetrics
Objective To investigate new risk factors for female fertility by analyzing the effects of environmental, social, and surgical factors on antral follicle counts (AFC) and anti‐Müllerian hormone (AMH) levels. Methods A total of 1513 women aged 20
Publikováno v:
Molecular Reproduction and Development. 87:887-898
This study was designed to investigate the protective effect of CD4+ CD25+ regulatory T cells (Tregs) against zona pellucida glycoprotein 3 peptide (pZP3) immunization-induced premature ovarian insufficiency (POI) in mice. A mouse POI model was induc