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Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Objective: Type 2 diabetes (T2D) is a chronic metabolic disorder characterized by reduced responsiveness of body cells to insulin, leading to elevated blood sugar levels. CNOT6L is involved in glucose metabolism, insulin secretion regulation
Externí odkaz:
https://doaj.org/article/8edb9befbc9b4f7789cb7e6aa05a8830
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 592-606 (2024)
Context The global prevalence of type 2 diabetes mellitus (T2DM) has increased significantly in recent decades. Despite numerous studies and systematic reviews, there is a gap in comprehensive and up-to-date evaluations in this rapidly evolving field
Externí odkaz:
https://doaj.org/article/7841839c02814afbaba3b0c1f6e8381a
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 544-561 (2024)
Context Diabetic peripheral neuropathy (DPN) results in an enormous burden and reduces the quality of life for patients. Considering there is no specific drug for the management of DPN, traditional Chinese medicine (TCM) has increasingly drawn attent
Externí odkaz:
https://doaj.org/article/44ea844e44dc4974b93de729ea064351
Autor:
Shinya Shikina, Yuki Yoshioka, Yi-Ling Chiu, Taiga Uchida, Emma Chen, Yin-Chu Cheng, Tzu-Chieh Lin, Yu-Ling Chu, Miyuki Kanda, Mayumi Kawamitsu, Manabu Fujie, Takeshi Takeuchi, Yuna Zayasu, Noriyuki Satoh, Chuya Shinzato
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Coral polyps are composed of four tissues; however, their characteristics are largely unexplored. Here we report biological characteristics of tentacles (Te), mesenterial filaments (Me), body wall (Bo), and mouth with pharynx (MP), using com
Externí odkaz:
https://doaj.org/article/5d1cb64384c5441d972c28877bbaa31a
Autor:
Jinlei Jiang, Xinyuan Cui, Yixin Huang, Dongmei Yan, Bensong Wang, Ziyang Yang, Mingrui Chen, Junhao Wang, Yuna Zhang, Guan Liu, Cheng Zhou, Shengsheng Cui, Jian Ni, Fuhua Yang, Daxiang Cui
Publikováno v:
Nano Biomedicine and Engineering, Vol 16, Iss 2, Pp 152-187 (2024)
In recent years, the deep integration of basic research and clinical translational research of nanotechnology and oncology has led to the emergence of a new branch, namely integrated nano-oncology. This is an emerging and important interdisciplinary
Externí odkaz:
https://doaj.org/article/75496c2dde7046c1b407292365b1f2a3
Autor:
Pengtao Jiao, Jianing Ma, Yuna Zhao, Xiaoxiao Jia, Haoran Zhang, Wenhui Fan, Xiaojuan Jia, Xiaoyuan Bai, Yiqi Zhao, Yongxu Lu, He Zhang, Jiayin Guo, Gang Pang, Ke Zhang, Min Fang, Minghua Li, Wenjun Liu, Geoffrey L. Smith, Lei Sun
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The Orthopoxvirus (OPXV) genus of the Poxviridae includes human pathogens variola virus (VARV), monkeypox virus (MPXV), vaccinia virus (VACV), and a number of zoonotic viruses. A number of Bcl-2-like proteins of VACV are involved in escaping the host
Externí odkaz:
https://doaj.org/article/e39d1e875dcf4cadb8064dd29db4dc45
Autor:
Chaoxin Tao, Min Zhao, Xiaohui Zhang, Jihong Hao, Qiuyue Huo, Jie Sun, Jiangtao Xing, Yuna Zhang, Jianhong Zhao, Huaipeng Huang
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Niemann-Pick Disease type C is a fatal autosomal recessive lipid storage disorder caused by NPC1 or NPC2 gene mutations and characterized by progressive, disabling neurological deterioration and hepatosplenomegaly. Herein, we iden
Externí odkaz:
https://doaj.org/article/5a4380d4ce4a43f7b6d392b830351422
Autor:
Shuiying Xiang, Yuechun Shi, Yahui Zhang, Xingxing Guo, Ling Zheng, Yanan Han, Yuna Zhang, Ziwei Song, Dianzhuang Zheng, Tao Zhang, Hailing Wang, Xiaojun Zhu, Xiangfei Chen, Min Qiu, Yichen Shen, Wanhua Zheng, Yue Hao
Publikováno v:
Opto-Electronic Advances, Vol 6, Iss 11, Pp 1-14 (2023)
Neuromorphic photonic computing has emerged as a competitive computing paradigm to overcome the bottlenecks of the von-Neumann architecture. Linear weighting and nonlinear spike activation are two fundamental functions of a photonic spiking neural ne
Externí odkaz:
https://doaj.org/article/5ac428cb41084c729a5701fa61e670f2
Autor:
Huizi Li, Wenhui Fan, Jie Min, Xiaoyuan Bai, Wenxian Yang, Heqiao Li, Yuna Zhao, Runshan Lin, Xiaojuan Jia, Wenjun Liu, Lei Sun
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108515- (2023)
Summary: Influenza B circulates annually and causes substantial disease burden in humans. However, little is known about the infection mechanisms of influenza B virus (IBV). Here, we find that the host factor cyclophilin A (CypA) facilitates IBV repl
Externí odkaz:
https://doaj.org/article/639de804e3114b26a90a1346a6922872