Zobrazeno 1 - 10
of 209
pro vyhledávání: '"YunYun Xu"'
Autor:
Miaoyan Wei, Rujiao Liu, Yunyun Xu, Xiaobing Chen, Chao Liu, Xueli Bai, Xiaochen Zhang, Shuiping Gao, Jialin Li, Zhen Sheng, Jianpo Lian, Wenliang Wang, Jian Zhang, Si Shi, Jin Xu, Xianjun Yu
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Chemotherapy remains the standard first-line treatment for pancreatic adenocarcinoma, but with limited efficacy. We aimed to explore the feasibility of adding the PARP inhibitor fuzuloparib to mFOLFIRINOX in the locally advanced/m
Externí odkaz:
https://doaj.org/article/cef3d052c08f444f99a82d9527d12961
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
In this study, we leveraged a sophisticated active learning model to enhance virtual screening for SQLE inhibitors. The model’s improved predictive accuracy identified compounds with significant advantages in binding affinity and thermodynamic stab
Externí odkaz:
https://doaj.org/article/2998d118180b415780ec518bfad72b92
Autor:
Xinjing Lv, Jie Min, Jie Huang, Hairong Wang, Song Wei, Chenxiao Huang, Jianfeng Dai, Zhengrong Chen, Huiting Zhou, Yunyun Xu, He Zhao, Zhuang Liu, Jian Wang
Publikováno v:
Advanced Science, Vol 11, Iss 39, Pp n/a-n/a (2024)
Abstract The overactivated immune cells in the infectious lesion may lead to irreversible organ damages under severe infections. However, clinically used immunosuppressive anti‐inflammatory drugs will usually disturb immune homeostasis and converse
Externí odkaz:
https://doaj.org/article/7982a4c093164a6f836b3432051b07a6
Publikováno v:
Ecological Indicators, Vol 165, Iss , Pp 112138- (2024)
Urban regeneration (UR) can improve the physical, social, economic, and ecological environment of urban areas, which is the key path to achieving Sustainable Development Goals (SDGs). However, quantitative assessments of the SDGs dynamics before and
Externí odkaz:
https://doaj.org/article/11fd867a81fd4aa58598cfb310dca45e
Autor:
Jianwei Wang, Hongli Yin, Gen Li, Di Wu, Yunyun Xu, Yanling Chen, Xiaodong Wang, Yujiao Xing, Ting Zhang, Danhong Fei, Pengcheng Yang, Fang Fang, Yanfang Tao, Xiaolu Li, Juanjuan Yu, Yang Yang, Zhiheng Li, Lei Shi, Zimu Zhang, Jian Pan
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Neuroblastoma (NB) is a common childhood tumor with a high incidence worldwide. The regulatory role of RNA N6-methyladenosine (m6A) in gene expression has attracted significant attention, and the impact of methyltransferase-like 14 (METTL14)
Externí odkaz:
https://doaj.org/article/277ddf3759754e5988e18f9a0e928085
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The incidence of exertional heat stroke (EHS) escalates during periods of elevated temperatures, potentially leading to persistent cognitive impairment postrecovery. Currently, effective prophylactic or therapeutic measures agains
Externí odkaz:
https://doaj.org/article/5217713e3741404db02331d5847f64e3
Autor:
Gen Li, Liya Ma, Chenxi Feng, Hongli Yin, Jianping Bao, Di Wu, Zimu Zhang, Xiaolu Li, Zhiheng Li, Chun Yang, Hairong Wang, Fang Fang, Xiaohan Hu, Mei Li, Lixiao Xu, Yunyun Xu, Hansi Liang, Tianquan Yang, Jianwei Wang, Jian Pan
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Glioblastoma (GBM) is a relatively prevalent primary tumor of the central nervous system in children, characterized by its high malignancy and mortality rates, along with the intricate challenges of achieving complete surgical res
Externí odkaz:
https://doaj.org/article/035888bb6d12430f89a248eb95aae939
Plasma extrachromosomal circular DNA as a potential diagnostic biomarker for nodular thyroid disease
Autor:
Meng Zhou, Wei Lv, Peng Han, Kai Sun, Ziqian Hao, Ling Gao, Yunyun Xu, Zhe Xu, Shanshan Shao, Shizhan Ma, Qingling Guo, Haiqing Zhang, Ke Liu, Fan Yang, Zhongshang Yuan, Guojun Wu, Changbin Yu, Yonglun Luo, Zhenyu Yao, Jiajun Zhao
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/525412bf19df43f59dd630b3c3daef3e
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Objective We investigated the impact of the long noncoding RNA LINC00958 on cellular activity and oxidative stress in osteoarthritis (OA). Methods We performed bioinformatics analysis via StarBase and luciferase reporter assays to predict an
Externí odkaz:
https://doaj.org/article/310a86206b2b4b2288bbd35e5743b694
Autor:
Tao Xia, Peng Xu, Yiping Mou, Xizhou Zhang, Shihao Song, Yucheng Zhou, Chao Lu, Qicong Zhu, Yunyun Xu, Weiwei Jin, Yuanyu Wang
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background Recurrence after resection is the main factor for poor survival. The relationship between clinicopathological factors and recurrence after curative distal pancreatectomy for PDAC has rarely been reported separately. Methods Patien
Externí odkaz:
https://doaj.org/article/59d29fd914de4e398b8002880a1f0b50