Zobrazeno 1 - 10
of 70
pro vyhledávání: '"YunLong Cheng"'
Autor:
Yixian Li, Peng Yang, Ran Meng, Shuting Xu, Lingling Zhou, Kang Qian, Pengzhen Wang, Yunlong Cheng, Dongyu Sheng, Minjun Xu, Tianying Wang, Jing Wu, Jinxu Cao, Qizhi Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1380-1399 (2024)
Intraneuronal dysproteostasis and extraneuronal microenvironmental abnormalities in Alzheimer's disease (AD) collectively culminate in neuronal deterioration. In the context of AD, autophagy dysfunction, a multi-link obstacle involving autophagy down
Externí odkaz:
https://doaj.org/article/8bd04ee938174169b40471e454fdf68d
Autor:
Kang Qian, Peng Yang, Yixian Li, Ran Meng, Yunlong Cheng, Lingling Zhou, Jing Wu, Shuting Xu, Xiaoyan Bao, Qian Guo, Pengzhen Wang, Minjun Xu, Dongyu Sheng, Qizhi Zhang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100938- (2024)
Alzheimer's disease is a neurodegenerative disease induced by multiple interconnected mechanisms. Peptide drug candidates with multi-modal efficacy generated from fusion strategy are suitable for addressing multi-facet pathology. However, clinical tr
Externí odkaz:
https://doaj.org/article/403f74994e394d2e9ed2d13b852fc61f
Autor:
Menghan Liu, Xin Wei, Xiaodong Xing, Yunlong Cheng, Zicheng Ma, Jiwu Ren, Xiaofeng Gao, Ajing Xu
Publikováno v:
Digital Health, Vol 10 (2024)
Background and Objective Osteoporotic fractures significantly impact individuals's quality of life and exert substantial pressure on the social pension system. This study aims to develop prediction models for osteoporotic fracture and uncover potenti
Externí odkaz:
https://doaj.org/article/1f4fee3fa6a741e298d9a0772487ecd6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Nitrogen (N) and phosphorus (P) are important nutrients for plant growth and development. Soil alkalization is one of the main obstacles limiting the sustainable development of agriculture. Northern Ningxia is located in the arid and semi-ar
Externí odkaz:
https://doaj.org/article/03a498d91b524bbd9358ba6ef0541e95
Autor:
Zhaoxin Li, Caisheng Zhou, Yumei Chen, Wentao Ma, Yunlong Cheng, Jinxin Chen, Yu Bai, Wei Luo, Na Li, Erxia Du, Sheng Li
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background In insects, an interplay between the activities of distinct hormones, such as juvenile hormone (JH) and 20-hydroxyecdysone (20E), regulates the progression through numerous life history hallmarks. As a crucial endocrine factor, JH
Externí odkaz:
https://doaj.org/article/14885b3ec5ce4ce1baa966e7d419d7b2
Autor:
Shuting Xu, Peng Yang, Kang Qian, Yixian Li, Qian Guo, Pengzhen Wang, Ran Meng, Jing Wu, Jinxu Cao, Yunlong Cheng, Minjun Xu, Qizhi Zhang
Publikováno v:
Bioactive Materials, Vol 11, Iss , Pp 300-316 (2022)
Compromised autophagy and defective lysosomal clearance significantly contribute to impaired neuronal proteostasis, which represents a hallmark of Alzheimer's disease (AD) and other age-related neurodegenerative disorders. Growing evidence has implic
Externí odkaz:
https://doaj.org/article/38cdd5f5995b4da78d49ad7b81c7193b
Publikováno v:
Agronomy, Vol 13, Iss 9, p 2356 (2023)
Soil salinization is detrimental to crop growth, agricultural yields, and environmental protection. Echinochloa frumentacea (Roxb.) Link is a pioneer species for the alteration of saline–alkali lands. In this paper, we examined the effects of inter
Externí odkaz:
https://doaj.org/article/fde3440df711483193b71507810aca6c
Publikováno v:
Metabolites, Vol 13, Iss 6, p 735 (2023)
Insect metabolites play vital roles in regulating the physiology, behavior, and numerous adaptations of insects, which has contributed to them becoming the largest class of Animalia. However, systematic metabolomics within the insects is still unclea
Externí odkaz:
https://doaj.org/article/6462f457561a411ab0abdcb1d1d0f9fb
Establishment of two-dimensional gel electrophoresis for soybean protein isolate and its application
Autor:
Xinkai Lu, Yaoming Cui, Junjun Guan, Xue Liu, Hao Zhu, Xuyang Ji, Jianzhang Zheng, Yunlong Cheng, Xiaofei Fu
Publikováno v:
Grain & Oil Science and Technology, Vol 3, Iss 3, Pp 100-109 (2020)
To optimize the conditions for the establishment of two-dimensional gel electrophoresis (2-DE) of soybean protein isolate (SPI), we investigated Ampholine mixture, anodic and cathodic electrolytes, loading amount of sample, acrylamide concentration,
Externí odkaz:
https://doaj.org/article/6d17c2a87f224ce3b134f99545944c12
Autor:
Ning Zheng, Weiqun Liu, Bifei Li, Huifang Nie, Jian Liu, Yunlong Cheng, Jichuang Wang, Haiyan Dong, Lee Jia
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Abstract Background Sorafenib is approved as a standard therapy for advanced hepatocellular carcinoma (HCC), but its clinical application is limited due to moderate therapeutic efficacy and high incidence of acquired resistance resulted from elevated
Externí odkaz:
https://doaj.org/article/4b14665e92b2410b9c44e4868f54ffbb