Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Yun-sil Lee"'
Autor:
Joonho Suh, Yun-Sil Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 66-85 (2024)
Abstract Mitochondria have been primarily considered intracellular organelles that are responsible for generating energy for cell survival. However, accumulating evidence suggests that mitochondria are secreted into the extracellular space under phys
Externí odkaz:
https://doaj.org/article/3e32a485f1de426f8e489af03598d9c3
Autor:
Seulgi Jeon, Hee Jin, Jin-Mo Kim, Youmin Hur, Eun Joo Song, Yoon-Jin Lee, Younghwa Na, Jaeho Cho, Yun-Sil Lee
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-15 (2023)
Abstract Background Heat shock protein 27 (HSP27) is overexpressed during pulmonary fibrosis (PF) and exacerbates PF; however, the upregulation of HSP27 during PF and the therapeutic strategy of HSP27 inhibition is not well elucidated. Methods We hav
Externí odkaz:
https://doaj.org/article/d0a375e845924f3cbfe10b963f6260a5
Autor:
Scisung Chung, Mi-Sun Kang, Dauren S. Alimbetov, Gil-Im Mun, Na-Oh Yunn, Yunjin Kim, Byung-Gyu Kim, Minwoo Wie, Eun A. Lee, Jae Sun Ra, Jung-Min Oh, Donghyun Lee, Keondo Lee, Jihan Kim, Seung Hyun Han, Kyong-Tai Kim, Wan Kyun Chung, Ki Hyun Nam, Jaehyun Park, ByungHoon Lee, Sunghoon Kim, Weixing Zhao, Sung Ho Ryu, Yun-Sil Lee, Kyungjae Myung, Yunje Cho
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Aminoacyl-tRNA synthetases possess unique domains. In this study the structure of the vertebrate IARS1 and EARS1 complex reveals that vertebrate IARS1 protects the DNA repair factor BRCA1 from proteolytic degradation via its UBX-fold domain.
Externí odkaz:
https://doaj.org/article/3a702a1ed24a45f995d55ea263c1b376
Autor:
Young Jo Yoo, Seulgi Jeon, Hee Jin, Hee Yeon Won, Mi Gyeong Jeong, Yeseul Cho, Eun Sook Hwang, Younghwa Na, Jaeho Cho, Yun-Sil Lee
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Pulmonary fibrosis (PF) is a progressive lung disease characterized by fibroblast accumulation and collagen deposition, resulting in lung scarring and impaired gas exchange. Current treatments for idiopathic pulmonary fibrosis (IPF) have
Externí odkaz:
https://doaj.org/article/d204f7a99021418ca804732268592569
Autor:
Kyeonghee Yoon, Sojung Choi, Hyung-Do Choi, Nam Kim, Sang Bong Jeon, Kyung-Min Lim, Hae-June Lee, Yun-Sil Lee
Publikováno v:
Journal of Electromagnetic Engineering and Science, Vol 20, Iss 4, Pp 307-319 (2020)
The growing concerns regarding the adverse biological effects of radiofrequency electromagnetic fields (RF-EMFs), which are generated by common electronic devices, on the human brain led us to investigate their impact on Alzheimer’s disease (AD). W
Externí odkaz:
https://doaj.org/article/7515ee03d2e44c49a7f053a8ed59d75e
Autor:
Joonho Suh, Yun-Sil Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 10, Pp 1673-1693 (2020)
Growth factors: untangling twin proteins A growth factor protein called GDF11 has potential for rejuvenation of heart, brain, and muscle tissues, but first its relationship with a twin growth factor (MSTN) must be unraveled. Although GDF11 and MSTN a
Externí odkaz:
https://doaj.org/article/b576f82da4d04d7999c6d61e8c98708b
Publikováno v:
Brain and Behavior, Vol 10, Iss 11, Pp n/a-n/a (2020)
Abstract Introduction Due to public concerns about deleterious biological consequences of radiofrequency electromagnetic fields (RF‐EMF), the potential effects of RF‐EMF on the central nervous system have received wide consideration. Methods Here
Externí odkaz:
https://doaj.org/article/15fdf9b3709645df84373dbcb6d5b03a
Autor:
Jin-Mo Kim, Hyun Yoo, Jee-Youn Kim, Sang Ho Oh, Jeong Wook Kang, Byung Rok Yoo, Song Yee Han, Cha Soon Kim, Won Hoon Choi, Eun-Jung Lee, Hyeong Ju Byeon, Won Jai Lee, Yun-Sil Lee, Jaeho Cho
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 3, Pp 959-970 (2018)
Background/Aims: Radiation-induced skin fibrosis is a common side effect of clinical radiotherapy. Our previous next-generation sequencing (NGS) study demonstrated the reduced expression of the regulatory α subunit of phosphatidylinositol 3-kinase (
Externí odkaz:
https://doaj.org/article/e87187b1a48a4ff7bdf3b053468fa91d
Autor:
Eun Ju Lee, Syed Sayeed Ahmad, Jeong Ho Lim, Khurshid Ahmad, Sibhghatulla Shaikh, Yun-Sil Lee, Sang Joon Park, Jun O. Jin, Yong-Ho Lee, Inho Choi
Publikováno v:
Cells, Vol 10, Iss 8, p 2083 (2021)
The objective of this study was to investigate fibromodulin (FMOD) and myostatin (MSTN) gene expressions during skeletal muscle aging and to understand their involvements in this process. The expressions of genes related to muscle aging (Atrogin 1 an
Externí odkaz:
https://doaj.org/article/9cddd1768ceb48cfaa2e413e57667f36
Autor:
Rabia Islam, Heein Yoon, Bong-soo Kim, Han-sol Bae, Hye-rim Shin, Woo-Jin Kim, Won-joon Yoon, Yun-Sil Lee, Kyung Mi Woo, Jeong-Hwa Baek, Hyun-Mo Ryoo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The conformation and function of a subset of serine and threonine-phosphorylated proteins are regulated by the prolyl isomerase Pin1 through isomerization of phosphorylated Ser/Thr-Pro bonds. Pin1 is intensely expressed in Sertoli cells, but
Externí odkaz:
https://doaj.org/article/c70b3e12080e47299670d20625366f94