Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Yun-Shien Lee"'
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Radiotherapy (RT) has numerous effects on the oral mucosa, primarily genetic alterations and changes in the microenvironment. The characteristics of oral leukoplakia (OL) may differ between patients who have received previous head
Externí odkaz:
https://doaj.org/article/2fa2557bf2e14f2c8ecba35e521b96d1
Autor:
Yu-Hua Huang, Yi-Chun Chen, Wei-Min Ho, Ren-Guey Lee, Ren-Hua Chung, Yu-Li Liu, Pi-Yueh Chang, Shih-Cheng Chang, Chaung-Wei Wang, Wen-Hung Chung, Shih-Jen Tsai, Po-Hsiu Kuo, Yun-Shien Lee, Chun-Chieh Hsiao
Publikováno v:
Journal of the Formosan Medical Association, Vol 123, Iss 6, Pp 701-709 (2024)
Background: Alzheimer's disease (AD) is complicated by multiple environmental and polygenetic factors. The accuracy of artificial neural networks (ANNs) incorporating the common factors for identifying AD has not been evaluated. Methods: A total of 1
Externí odkaz:
https://doaj.org/article/0f488051898c48c983945116815d755d
Autor:
Hui‐Tzu Chien, Chia‐Lung Tsai, Chi‐Kuan Young, Yun‐Shien Lee, Chun‐Ta Liao, Chih‐Ching Yeh, Angel Chao, Kai‐Lun Cho, Ching‐Han Chen, Shiang‐Fu Huang
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 19174-19187 (2023)
Abstract Introduction In the era of precision preventive medicine, susceptible genetic markers for oro‐/hypopharyngeal squamous cell carcinoma (OPSCC) have been investigated for genome‐wide associations. Materials and Methods A case–control stu
Externí odkaz:
https://doaj.org/article/104d8a84db014219a063c35fd7ddc6cd
Autor:
Chun-Ju Yang, Hao-Chun Chang, Pin-Cheng Sung, Mao-Cheng Ge, Hsiang-Yu Tang, Mei-Ling Cheng, Hao-Tsai Cheng, Hong-Hsue Chou, Cheng-Yu Lin, Wey-Ran Lin, Yun-Shien Lee, Sen-Yung Hsieh
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113591- (2024)
Summary: While fecal microbiota transplantation (FMT) shows promise in treating human diseases, oral capsule FMT is more accepted and accessible to patients. However, microbe selection in the upper gastrointestinal tract (UGIT) through oral administr
Externí odkaz:
https://doaj.org/article/89a575187a3240bc9d99d9a51c5cd889
Autor:
Shuen-Iu Hung, Mu-Tzu Chu, Ming-Mo Hou, Yun-Shien Lee, Chan-Keng Yang, Sung-Yu Chu, Feng-Yuan Liu, Hung-Chih Hsu, Shih-Cheng Pao, Yu-Chuan Teng, Chun-Bing Chen, Angel Chao, Wen-Hung Chung, John Wen-Cheng Chang, Chyong-Huey Lai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115928- (2023)
Neoantigen-reactive cytotoxic T lymphocytes play a vital role in precise cancer cell elimination. In this study, we demonstrate the effectiveness of personalized neoantigen-based T cell therapy in inducing tumor regression in two patients suffering f
Externí odkaz:
https://doaj.org/article/bad26cd210654a5bb7eb4d83a3412e3b
Autor:
Angel Chao, Ren-Chin Wu, Chiao-Yun Lin, Lee-Yu Lee, Chia-Lung Tsai, Yun-Shien Lee, Chin-Jung Wang
Publikováno v:
Journal of Obstetrics and Gynaecology, Vol 43, Iss 1 (2023)
Adenomyosis is a condition characterised by the invasion of endometrial tissues into the uterine myometrium, the molecular pathogenesis of which remains incompletely elucidated. Lesion profiling with next-generation sequencing (NGS) can lead to the i
Externí odkaz:
https://doaj.org/article/f5248dd74f354e148d0e883483653bd5
Autor:
Haiqin Jiang, Chuang-Wei Wang, Zhaoxi Wang, Yufei Dai, Yanping Zhu, Yun-Shien Lee, Yang Cao, Wen-Hung Chung, Songying Ouyang, Hongsheng Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-21 (2022)
Abstract Background Severe cutaneous adverse drug reactions (SCARs) are a group of serious clinical conditions caused by immune reaction to certain drugs. The allelic variance of human leukocyte antigens of HLA-B*13:01 has been strongly associated wi
Externí odkaz:
https://doaj.org/article/05a7246cf0b449e69c5da26b991e794d
Autor:
Liang-Jie Wang, Chie-Pein Chen, Yun-Shien Lee, Pui-Sze Ng, Geen-Dong Chang, Yu-Hsuan Pao, Hsiao-Fan Lo, Chao-Hsiang Peng, Mei-Leng Cheong, Hungwen Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Trophoblast stem cells can be derived from human blastocysts and first-trimester, but not term, cytotrophoblasts. Here the authors show that induction efficiency of cytotrophoblast is determined by antagonism between GCM1 and ΔNp63α and manipulatin
Externí odkaz:
https://doaj.org/article/f1760c12c36e4495b73d44811c3197a6
Autor:
Pei-Wen Wu, Ta-Jen Lee, Shih-Wei Yang, Yenlin Huang, Yun-Shien Lee, Che-Fang Ho, Chien-Chia Huang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Maxillary sinus fungal balls (MSFBs) mostly occur in older individuals and demonstrate female predominance. Early diagnosis is important to avoid treatment delays. Intralesional hyperdensity (IH) indicates the presence of heavy metal deposit
Externí odkaz:
https://doaj.org/article/812e8687d63045ff91ab3f3c19732493
Autor:
Tong-Hong Wang, Chin-Chuan Chen, Yann-Lii Leu, Yun-Shien Lee, Jang-Hau Lian, Hsi-Lung Hsieh, Chi-Yuan Chen
Publikováno v:
Journal of the Formosan Medical Association, Vol 120, Iss 9, Pp 1695-1705 (2021)
Background/purpose: Palbociclib is an FDA-approved cyclin-dependent kinase (CDK) 4/6 inhibitor that has been clinically proven to be effective in breast cancer. However, its use in oral cancer is not well researched. In this study, we investigated th
Externí odkaz:
https://doaj.org/article/daf17f6fac1b488ba297c9895c342afe