Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Yun-Seob Song"'
Autor:
Jae-Heon Kim, Hee-Jo Yang, Chang-Ho Lee, Youn-Soo Jeon, Jae-Joon Park, Kwang-Woo Lee, Jae-Ho Kim, Su-Yeon Park, Su-Jung Song, Yon-Hee Kim, Ah-Rim Moon, Ji-Hye Lee, Yun-Seob Song
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 778 (2021)
Background: The mTOR signaling pathway is inactivated by AMPK’s tumor-suppressing function. It is recognized that ubiquitin conjugating enzyme 2O (UBE2O), which directly targets AMPK for ubiquitination and degradation, is intensified in human cance
Externí odkaz:
https://doaj.org/article/9ebcef769bfc48f9af809579b4abe8d8
Publikováno v:
International Neurourology Journal, Vol 27, Iss 4, Pp 271-279 (2023)
Purpose Ischemia of the bladder can occur if neovascular formation cannot keep pace with hypoxia induced by chronic bladder outlet obstruction (BOO). The aim of this study was to examine changes in angiogenesis growth factor expression generated by c
Externí odkaz:
https://doaj.org/article/8f12f25a98ee411b8a3ffc9c21ace23f
Publikováno v:
International Neurourology Journal, Vol 27, Iss 4, Pp 234-242 (2023)
Purpose Men with diabetes mellitus (DM) often present with severe erectile dysfunction (ED). This ED is less responsive to current pharmacological therapies. If we know the upregulated or downregulated genes of diabetic ED, we can inhibit or enhance
Externí odkaz:
https://doaj.org/article/aa891271d3a042279636da29d80f169f
Autor:
Jae Heon Kim, Hoonhee Seo, Sukyung Kim, Md Abdur Rahim, Sujin Jo, Indrajeet Barman, Hanieh Tajdozian, Faezeh Sarafraz, Ho-Yeon Song, Yun Seob Song
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8943 (2024)
Numerous human pathologies, such as neoplasia, are related to particular bacteria and changes in microbiome constituents. To investigate the association between an imbalance of bacteria and prostate carcinoma, the microbiome and gene functionality fr
Externí odkaz:
https://doaj.org/article/59ec6d0d6aee414ab95b1b923dffe9d1
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5519 (2024)
A promising de novo approach for the treatment of Castration-resistant prostate cancer (CRPC) exploits cell-mediated enzyme prodrug therapy comprising cytosine deaminase (CD) and fluorouracil (5-FC). The aim of this study was to determine the potenti
Externí odkaz:
https://doaj.org/article/93f4c3252cf542329135504d59f643d1
Autor:
Jae Heon Kim, Hee Jo Yang, Kwang Woo Lee, Jae Joon Park, Chang-Ho Lee, Youn Soo Jeon, Jae Ho Kim, Suyeon Park, Su Jung Song, Ji-Hye Lee, Ahrim Moon, Yon Hee Kim, Yun Seob Song
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1703 (2023)
Background: Ubiquitin-specific protease 11 (USP11), one of the principal phosphatase and tensin homolog (PTEN) deubiquitinases, can reserve PTEN polyubiquitination to maintain PTEN protein integrity and inhibit PI3K/AKT pathway activation. The aim of
Externí odkaz:
https://doaj.org/article/cfac16977dbc47aa99c6e00d0099a056
Publikováno v:
Prostate International, Vol 9, Iss 4, Pp 215-220 (2021)
Purpose: This study aimed to evaluate benign prostatic hyperplasia (BPH) diagnosis rate and the changing landscape of medical and surgical management of BPH over the last decade using national population data of South Korea. Methods: The present stud
Externí odkaz:
https://doaj.org/article/77f6172c7b81458b995e6bd11111feb4
Autor:
Jae Heon Kim, Ji Sung Shim, Jong Wook Kim, Seung Whan Doo, Jae Hyun Bae, Ju Han Lee, Yun Seob Song, Je Jong Kim, Du Geon Moon
Publikováno v:
The World Journal of Men's Health, Vol 38, Iss 3, Pp 345-352 (2020)
Purpose: To validate a novel arteriogenic erectile dysfunction (ED) model with atherosclerosis (AS) based on molecular and histologic evidence induced by chronic pelvic ischemia (CPI) and determine effect of phosphodiesterase-5 inhibitor treatment.
Externí odkaz:
https://doaj.org/article/bf6ac439162f458a87c5c9fb0949044d
Publikováno v:
International Neurourology Journal, Vol 25, Iss Suppl 2, Pp S114-119 (2021)
Purpose Raised cerebral titers of acetylcholine have notable links with storage symptomatology related to lower urinary tract symptoms. The hippocampus contributes to the normal control of continence in the majority of instances (circuit 3). Owing to
Externí odkaz:
https://doaj.org/article/8f9622dfe20f450ebeba7f460fe9a41b
Publikováno v:
International Neurourology Journal, Vol 25, Iss Suppl 2, Pp S106-113 (2021)
Purpose The lower urinary tract is believed to be centrally regulated with the involvement of a range of neurotransmitters. The parasympathetic excitatory input to the urinary bladder is suppressed when the serotonergic system is activated, and there
Externí odkaz:
https://doaj.org/article/43ce72e7b80a4b0bae0824013ce34af5