Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yun-Qing Song"'
Autor:
Xiao-Ya Qin, Xu-Dong Hou, Guang-Hao Zhu, Yuan Xiong, Yun-Qing Song, Liang Zhu, Dong-Fang Zhao, Shou-Ning Jia, Jie Hou, Hui Tang, Guang-Bo Ge
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Pancreatic lipase (PL) inhibitor therapy has been validated as an efficacious way for preventing and treating obesity and overweight. In the past few decades, porcine PL (pPL) is widely used as the enzyme source for screening the PL inhibitors, which
Externí odkaz:
https://doaj.org/article/6b7b4ba16ff7483bbf0737c743499006
Autor:
Zhao-Hui Sun, Jing Chen, Yun-Qing Song, Tong-Yi Dou, Li-Wei Zou, Da-Cheng Hao, Hai-Bin Liu, Guang-Bo Ge, Ling Yang
Publikováno v:
Chinese Medicine, Vol 14, Iss 1, Pp 1-15 (2019)
Abstract Background Human carboxylesterases (hCES) are key serine hydrolases responsible for the hydrolysis of a wide range of endogenous and xenobiotic esters. Although it has been reported that some ginsenosides can modulate the activities of vario
Externí odkaz:
https://doaj.org/article/4d3667e289db486d9e846e2651a677dd
Autor:
Yun-Qing Song, Rong-Jing He, Dan Pu, Xiao-Qing Guan, Jin-Hui Shi, Yao-Guang Li, Jie Hou, Shou-Ning Jia, Wei-Wei Qin, Sheng-Quan Fang, Guang-Bo Ge
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Human carboxylesterase 2 (CES2), one of the most abundant hydrolases distributed in the small intestine, has been validated as a key therapeutic target to ameliorate the intestinal toxicity caused by irinotecan. This study aims to discover efficaciou
Externí odkaz:
https://doaj.org/article/b06ce37907fe4a529b4545695cd09554
Autor:
Chun-Yu Li, Hao-Nan Wang, Rong-Jing He, Jian Huang, Li-Lin Song, Yun-Qing Song, Peng-Chao Huo, Jie Hou, Guang Ji, Guang-Bo Ge
Publikováno v:
Food & Function. 13:3318-3328
Following the screening of more than one hundred natural products, amentoflavone (AMF) displayed the strongest lsBSH inhibition activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795d80e496c81de1f66c05b31a5a425e
https://doi.org/10.1039/d1fo03277a
https://doi.org/10.1039/d1fo03277a
Autor:
Jin-Hui Shi, Bei Zhao, Li-Lin Song, Yu-Qing Song, Meng-Ru Sun, Tian Tian, Hong-Yu Chen, Yun-Qing Song, Jian-Ming Sun, Guang-Bo Ge
Publikováno v:
Chinese Chemical Letters. :108405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c28ef57417cf254372eeede2de35dc2
https://doi.org/10.1016/j.cclet.2023.108405
https://doi.org/10.1016/j.cclet.2023.108405
Autor:
Xiao-Qing Guan, Yuan Xiong, Qi Jia, Weiliang Zhu, Yun-Qing Song, Sheng-Quan Fang, Yong Zhang, Sanfeng Dong, Kun Zou, Yitian Zhao, Yanqing Yang, Li Zhao, Guang-Bo Ge, Kaixian Chen, Bo Li
Publikováno v:
ChemMedChem. 16:388-398
Mammalian carboxylesterases (CES) are key enzymes that participate in the hydrolytic metabolism of various endogenous and exogenous substrates. Human carboxylesterase 2A (hCES2A), mainly distributed in the small intestine and colon, plays a significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc836142959220e162720020164c826
https://doi.org/10.1002/cmdc.202000581
https://doi.org/10.1002/cmdc.202000581
Autor:
Jing-Fang Zhang, Guang-Bo Ge, Sheng Lin, Gui-Hua Tian, Gui-Yang Xia, Yan-Cheng Li, Wan-Chao Zhong, Yun-Qing Song
Publikováno v:
Journal of Natural Products. 83:2940-2949
In a continuing search for potential inhibitors against human carboxylesterases 1A1 and 2A1 (hCES1A1 and hCES2A1), an EtOAc extract of the roots of Paeonia lactiflora showed strong hCES inhibition activity. Bioassay-guided fractionation led to the is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abdc87ff412aa24c6f66e0d9c67bd8c4
https://doi.org/10.1021/acs.jnatprod.0c00464
https://doi.org/10.1021/acs.jnatprod.0c00464
Autor:
Wei-Wei Qin, Lu Wang, Xiao-Qing Guan, Pei-Fang Song, Yuan Xiong, Rong-Jing He, Peng-Chao Huo, Hui Tang, Guang-Bo Ge, Yun-Qing Song, Feng Zhang
Publikováno v:
Food & Function. 11:8680-8693
Human carboxylesterase 1A1 (hCES1A) is a promising target for the treatment of hyperlipidemia and obesity-associated metabolic diseases. To date, the highly specific and efficacious hCES1A inhibitors are rarely reported. This study aims to find poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758a4dd609b2f57d90841bf66309be9d
https://doi.org/10.1039/d0fo01732a
https://doi.org/10.1039/d0fo01732a
Autor:
Tong-Yi Dou, Yun-Qing Song, Hai-Bin Liu, Ling Yang, Li-Wei Zou, Guang-Bo Ge, Jing Chen, Zhao-Hui Sun, Da-Cheng Hao
Publikováno v:
Chinese Medicine, Vol 14, Iss 1, Pp 1-15 (2019)
Chinese Medicine
Chinese Medicine
Background Human carboxylesterases (hCES) are key serine hydrolases responsible for the hydrolysis of a wide range of endogenous and xenobiotic esters. Although it has been reported that some ginsenosides can modulate the activities of various enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec23df30d4e248c561ddaea6d596c4f3
https://doaj.org/article/4d3667e289db486d9e846e2651a677dd
https://doaj.org/article/4d3667e289db486d9e846e2651a677dd
Autor:
Xiao-Ya, Qin, Xu-Dong, Hou, Guang-Hao, Zhu, Yuan, Xiong, Yun-Qing, Song, Liang, Zhu, Dong-Fang, Zhao, Shou-Ning, Jia, Jie, Hou, Hui, Tang, Guang-Bo, Ge
Publikováno v:
Frontiers in nutrition. 9
Pancreatic lipase (PL) inhibitor therapy has been validated as an efficacious way for preventing and treating obesity and overweight. In the past few decades, porcine PL (pPL) is widely used as the enzyme source for screening the PL inhibitors, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c770c7db744f8b9bc2db1a70b3cb4d95
https://pubmed.ncbi.nlm.nih.gov/35284458
https://pubmed.ncbi.nlm.nih.gov/35284458