Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yun-Li Ma"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283908 (2023)
Long-term memory formation requires de novo RNA and protein synthesis. By using the differential display-polymerase chain reaction strategy, we have presently identified the Nedd4 family interacting protein 1 (Ndfip1) cDNA fragment that is differenti
Externí odkaz:
https://doaj.org/article/ff08ed027d5044c3b6a9bae53f24bdb8
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Galectin-3, a member of the galectin protein family, has been found to regulate cell proliferation, inhibit apoptosis and promote inflammatory responses. Galectin-3 is also expressed in the adult rat hippocampus, but its role in learning and memory f
Externí odkaz:
https://doaj.org/article/2b23373bc0924e8d82b818e52f3e74a8
Publikováno v:
Molecular Therapy
The amyloid precursor protein (APP) intracellular domain (AICD) is implicated in the pathogenesis of Alzheimer’s disease (AD), but post-translational modification of AICD has rarely been studied and its role in AD is unknown. In this study, we exam
Publikováno v:
British Journal of Pharmacology. 176:1793-1810
Background and purpose Protein inhibitor of activated STAT1 (PIAS1) is phosphorylated by IKKα at Ser90 in a PIAS1 E3 ligase activity-dependent manner. Whether PIAS1 is also phosphorylated at other residues and the functional significance of these ad
Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The methyl-CpG-binding protein 2 gene, MECP2, is an X chromosome-linked gene encoding the MeCP2 protein, and mutations of MECP2 cause Rett syndrome (RTT). Previous study has shown that re-expression of SUMO-modified MeCP2 in Mecp2-null neurons rescue
Autor:
Wei Ju Lee, Yan-Chu Chen, Yun-Li Ma, Jong Ling Fuh, Chih-Chieh Tao, Eminy H.Y. Lee, Wei-Lun Hsu, Kuang-Min Cheng, Chih-Chang Chao
Publikováno v:
Cell Death and Differentiation
Amyloid-β (Aβ) oligomers largely initiate the cascade underlying the pathology of Alzheimer's disease (AD). Galectin-3 (Gal-3), which is a member of the galectin protein family, promotes inflammatory responses and enhances the homotypic aggregation
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Protein inhibitor of activated STAT1 (PIAS1) is phosphorylated by IKKα at Ser(90) in a PIAS1 E3 ligase activity‐dependent manner. Whether PIAS1 is also phosphorylated at other residues and the functional significance of the
Publikováno v:
Alzheimer's & Dementia. 15:P315-P316
Publikováno v:
Journal of Neuroscience. 34:9574-9589
cAMP-responsive element binding protein (CREB) phosphorylation and signaling plays an important role in long-term memory formation, but other posttranslational modifications of CREB are less known. Here, we found that CREB1Δ, the short isoform of CR
Publikováno v:
Neuropsychopharmacology
Signal transducer and activator of transcription-1 (STAT1) has an important role in inflammation and the innate immune response, but its role in the central nervous system is less well understood. Here, we examined the role of STAT1 in spatial learni