Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yun-Ju Kwon"'
Autor:
Jung Woong Yoon, Myoung Ok Kim, Sangsu Shin, Woo-Sung Kwon, Soo Hyun Kim, Yun-Ju Kwon, Sang In Lee
Publikováno v:
Toxics, Vol 12, Iss 7, p 487 (2024)
Antimicrobial peptides (AMPs) function to extensively suppress various problematic factors and are considered a new alternative for improving livestock health and enhancing immunomodulation. In this study, we explored whether AMP regulation has posit
Externí odkaz:
https://doaj.org/article/3d25c2a5494d475ea92e70c8b2287ff4
Publikováno v:
Journal of Apiculture. 34:125-129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::286f092c7e74ac0fd10dc6dea0332bd9
https://doi.org/10.17519/apiculture.2019.06.34.2.125
https://doi.org/10.17519/apiculture.2019.06.34.2.125
Autor:
Ye-eun Jang, Jenita Immanuel, Jin-ri Lee, Yu-jin Jang, Yun Ju Kwon, Hyun Sook Kwon, Jung-Woog Shin, Sanguk Yun
Publikováno v:
Journal of Lipid and Atherosclerosis. 11:272
The endothelial inflammatory response plays an important role in atherogenesis by inducing nuclear factor (NF)κB-dependent cell adhesion molecule expression and monocyte recruitment. Here, we screened for natural ligands and investigated the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1154a0457a3c0f9df85d49cd3b54a0
https://doi.org/10.12997/jla.2022.11.3.272
https://doi.org/10.12997/jla.2022.11.3.272
Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid
Autor:
Tae-Wook Chung, Eun-Yeong Kim, Chang Woo Han, So Young Park, Mi Suk Jeong, Dahye Yoon, Hee-Jung Choi, Ling Jin, Mi-Ju Park, Yun Ju Kwon, Hanna Lee, Keuk-Jun Kim, Kang Hyun Park, Suhkmann Kim, Se Bok Jang, Ki-Tae Ha
Publikováno v:
Cancers
Cancers, Vol 11, Iss 7, p 963 (2019)
Volume 11
Issue 7
Cancers, Vol 11, Iss 7, p 963 (2019)
Volume 11
Issue 7
Lactate dehydrogenase A (LDHA) is an important enzyme responsible for cancer growth and energy metabolism in various cancers via the aerobic glycolytic pathway. Here, we report that machilin A (MA), which acts as a competitive inhibitor by blocking t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da445edbb9646567a04483ab6a9198be
https://pubmed.ncbi.nlm.nih.gov/31324019
https://pubmed.ncbi.nlm.nih.gov/31324019
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:1406-1410
Dihydrofolate reductase (DHFR) has been confirmed to be a novel target for antibacterial drug development. In this study, we determined that a fungal metabolite from Stachybotrys sp. FN298 can inhibit the DHFR of Staphylococcus aureus. Its structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32d704c795aeaf1951ac11b504a28f65
https://doi.org/10.1248/bpb.b14-00108
https://doi.org/10.1248/bpb.b14-00108
Publikováno v:
Journal of Microbiology and Biotechnology. 23:184-188
In the continued search for inhibitors of enoyl-acyl carrier protein (ACP) reductase, we found that four acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761 potently inhibited bacterial enoyl-ACP reductases of Staphylococcus aureus, Stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab75141271c4539631bd30226f1765e
https://doi.org/10.4014/jmb.1209.09038
https://doi.org/10.4014/jmb.1209.09038
Autor:
Heung-Mook Shin, Seung Tack Oh, Dong-Il Kim, Seongmi Lee, Yura Choi, Ha Jin Jeong, Jae-Hyun Han, Yun Ju Kwon, Hanna Lee, Songhee Jeon
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 24
Background Despite the benefits from different options of therapy for breast cancer, resistance of the disease to these therapies is rising and a novel agent is needed. Erythro-austrobailignan-6 (EA6) exhibits anti-cancer activity. However, the detai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28443b200574acbbb9de44d8eaac03dc
https://pubmed.ncbi.nlm.nih.gov/28160858
https://pubmed.ncbi.nlm.nih.gov/28160858
Publikováno v:
Journal of Natural Products. 75:271-274
Flavimycins A (1) and B (2), novel dimeric 1,3-dihydroisobenzofurans, were isolated as inhibitors of peptide deformylase from cultures of Aspergillus flavipes. Their chemical structures were established by NMR and MS data analysis. Compounds 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5a921336fe48ff0aed0472f55c69c6
https://doi.org/10.1021/np200720v
https://doi.org/10.1021/np200720v
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 74:390-393
Two highly hydroxylated 1,3-dihydroisobenzofurans, FR198248 (1) and FR202306 (2), were isolated as peptide deformylase (PDF) inhibitors from Aspergillus flavipes. Compounds 1 and 2 inhibited Staphylococus aureus PDF with IC(50) values of 3.6 and 2.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485a408c88e4faa22fbbb66412e37183
https://doi.org/10.1271/bbb.90565
https://doi.org/10.1271/bbb.90565
Publikováno v:
Biological and Pharmaceutical Bulletin. 32:2061-2064
Bacterial enoyl-acyl carrier protein (ACP) reductase has been confirmed as a novel target for antibacterial drug development. In this study, we determined that a fungal metabolite from Sporothrix sp. FN611 potently inhibited the enoyl-ACP reductase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366f62d410f9915eac8f039ff647679c
https://doi.org/10.1248/bpb.32.2061
https://doi.org/10.1248/bpb.32.2061