Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yun-Jian HUANG"'
Autor:
Chun-wei Xu, Wen-xian Wang, Yan-ping Chen, Yu Chen, Wei Liu, Li-hua Zhong, Fang-fang Chen, Wu Zhuang, Zheng-bo Song, Xiao-hui Chen, Yun-jian Huang, Yan-fang Guan, Xin Yi, Tang-feng Lv, Wei-feng Zhu, Jian-ping Lu, Xiao-jiang Wang, Yi Shi, Xian-dong Lin, Gang Chen, Yong Song
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background ALK rearrangement-advanced NSCLC patients respond to crizotinib. ALK rearrangement is currently determined with RT-PCR. VENTANA IHC is a standard method to identify ALK protein overexpression in NSCLC; however, VENTANA IHC has rar
Externí odkaz:
https://doaj.org/article/670ffea6efa64531975757d75f66d41a
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 45, Iss 1, Pp 55-61 (2020)
Objective To explore the effects and mechanism of high expression of ARNO (ARF nucleotide-binding-site opener) on the permeability of human renal glomerular endothelial cells (HRGECs) under high glucose conditions. Methods HRGECs were cultured in vit
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 44, Iss 8, Pp 652-658 (2019)
Objective To explore the effect of Slit2/ROBO1 protein (Slit2/ROBO1) signaling pathway in high glucose-induced epithelial-mesenchymal transdifferentiation (EMT) and its mechanism. Methods Human renal tubular epithelial cells (HK-2) were cultured in v
Background: Increasing evidence suggests that de novo T790M mutation occurs at a low frequency in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC). However, the effects of this mutation on the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4aaf6fdfc2bd2305d561fa8995c60d
https://doi.org/10.21203/rs.3.rs-338298/v1
https://doi.org/10.21203/rs.3.rs-338298/v1
Autor:
You-cai Zhu, Wen-Xian Wang, Biao Wu, Wu Zhuang, Chunwei Xu, Yun-jian Huang, Mei-juan Wu, Yanping Chen, Quxia Zhang, Kai-qi Du
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
BACKGROUND RET rearrangements have been reported in 30% of papillary thyroid carcinomas and 1-2% of non-small cell lung cancer (NSCLC). In these tumors, RET gene fusion product provides a constitutively active tyrosine kinase (TKR), leading to uncont
Autor:
Xu-fei ZHU, Tao GUAN, Jun-hui LIU, Shi-hui HOU, Cheng-fang HU, Yi LI, Lu-yao TANG, Jun ZHANG, Yun-jian HUANG
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 43, Iss 6, Pp 451-458 (2018)
Objective To validate the glomerular vascular lesions percentage score (GVLPS) system in renal vascular lesions of Henoch-Schönlein purpura nephritis (HSPN) in a single-center cohort. Methods Clinical and renal histopathological data of 140 patients
Autor:
Zhangzhou Huang, Rong-Rong Chen, Chunwei Xu, Wenxian Wang, Tang Feng Lv, Jianping Lu, Wu Zhuang, Yun-jian Huang, Gang Chen, Xiandong Lin, Li-hua Zhong, Weifeng Zhu, Wei Liu, Yong Song, Xiaojiang Wang, Yanfang Guan, Yi Shi, Yanping Chen, Fangfang Chen, Xin Yi
Publikováno v:
Journal of Thoracic Disease. 10:2991-2998
Background: Advanced non-small cell lung cancer (NSCLC) patients who harbor anaplastic lymphoma kinase ( ALK ) rearrangement are sensitive to an ALK inhibitor (crizotinib), but not all ALK -positive patients benefit equally from crizotinib treatment.
Publikováno v:
Journal of Cellular and Molecular Medicine
Nuclear factor‐kappa B (NF‐κB) as a prognostic marker remains unclear in non‐small cell lung cancer (NSCLC). Here, we studied NF‐κB‐p65 (p65) expression and phosphorylated NF‐κB‐p105 (p‐p105) expression in NSCLC and correlated the
Autor:
Kan Jiang, Qian Miao, Haipeng Xu, Weifeng Zhu, Cheng Huang, Peisha Huang, Wu Zhuang, Xiaohui Chen, Dan Hu, Chao Li, Gen Lin, Tony Mok, Yun-jian Huang, Xiandong Lin, Xirong Fan
Publikováno v:
Journal of Thoracic Oncology. 12:1536-1543
The extent to which intratumoral heterogeneity of programmed death ligand 1 (PD-L1) expression causes discordance of PD-L1 expression between paired samples remains unclear. Here, PD-L1 status was compared between whole sections from NSCLCs and the c
Autor:
Kai-qi Du, Yun-jian Huang, Yanping Chen, Gen Lin, You-cai Zhu, Chunwei Xu, Mei-juan Wu, Wu Zhuang, Mei-yu Fang, Gang Chen, Wen-Xian Wang
Publikováno v:
Thoracic Cancer. 8:417-422
Background c-MET has recently been identified as a promising novel target in non-small cell lung cancer (NSCLC). We detected the consistency of c-MET gene amplification in metastatic lymph nodes and tumor tissues of NSCLC patients and discuss the cli