Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yun-Gang Bai"'
Publikováno v:
BMC Pharmacology and Toxicology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Vascular disease is a common and often severe complication in diabetes mellitus. Hyperglycemia and hypertension are considered to be two of the leading risk factors for vascular complications in diabetic patients. However, few pha
Externí odkaz:
https://doaj.org/article/13b941123fc145f993c5b62c6bf39245
Autor:
Jiu-Hua Cheng, Li-Fan Zhang, Fang Gao, Yun-Gang Bai, Marco Boscolo, Xiao-Feng Huang, Xiang Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97737 (2014)
BACKGROUND: To elucidate further from the biomechanical aspect whether microgravity-induced cerebral vascular mal-adaptation might be a contributing factor to postflight orthostatic intolerance and the underlying mechanism accounting for the potentia
Externí odkaz:
https://doaj.org/article/046d980f3a564f3bb474dd325f693d55
Autor:
Jun-Xiang Bao, Hui Chang, Yong-Gang Lv, Jin-Wen Yu, Yun-Gang Bai, Huan Liu, Yue Cai, Ling Wang, Jin Ma, Yao-Ming Chang
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30387 (2012)
Lysosomal exocytosis and fusion to cellular membrane is critical in the oxidative stress formation of endothelium under apoptotic stimulus. We investigated the role therein of it in hyperglycaemia-induced endothelial dysfunction. The lysosome-membran
Externí odkaz:
https://doaj.org/article/b64f9845423b424aac6fe9d443463039
Autor:
Qiang Lv, Xianyang Zhu, Zhongchao Wang, Man-Jiang Xie, Yun-Gang Bai, Huan Liu, Jun-Xiang Bao, Shaohua Li, Yue Wu, Zhijie Yue, Qiguang Wang, Jin Ma
Publikováno v:
The FASEB Journal. 33:13358-13366
Previous studies have demonstrated cardiac and vascular remodeling induced by microgravity exposure. Yet, as the most important branch of vasculatures circulating the heart, the coronary artery has been seldomly studied about its adaptations under mi
Autor:
Xinling Ren, Jiang Min, Jiu-Hua Cheng, Qixin Shi, Yiquan Yan, Zhongchao Wang, Yun-Gang Bai, Jing Yang, Shaohua Li, Dong Dong, Yan Ma, Jin Ma, Lyu Qiang, Huan Liu
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(2)
High-altitude pulmonary hypertension (HAPH) is a severe and progressive disease caused by chronic hypoxia and subsequent pulmonary vascular remodeling. No cure is currently available owing to an incomplete understanding about vascular remodeling. It
Autor:
Jin Ma, Ji-Bo Song, Yun-Gang Bai, Jiu-Hua Cheng, Man-Jiang Xie, Bin Zhang, Hong-Zhe Ma, Li Chen
Publikováno v:
Cell Proliferation
Objectives Postflight orthostatic intolerance has been regarded as a major adverse effect after microgravity exposure, in which cerebrovascular adaptation plays a critical role. Our previous finding suggested that dedifferentiation of vascular smooth
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 96:772-782
Recent studies have suggested that microgravity-induced arterial remodelling contributes to post-flight orthostatic intolerance and that multiple mechanisms are involved in arterial remodelling. However, the initial mechanism by which haemodynamic ch
Autor:
Zhijun Dai, Man-Jiang Xie, Yinbin Zhang, Bao-Feng Wang, Yu-Guang Ma, Zhongwei Wang, Liang Liang, Yun-Gang Bai
Publikováno v:
Journal of Molecular Endocrinology. 59:191-204
Hyperglycemia and hypertension are considered to be the two leading risk factors for vascular disease in diabetic patients. However, few pharmacologic agents could provide a combinational therapy for controlling hyperglycemia and hypertension at the
Publikováno v:
BMC Pharmacology and Toxicology, Vol 18, Iss 1, Pp 1-15 (2017)
BMC Pharmacology & Toxicology
BMC Pharmacology & Toxicology
Background Vascular disease is a common and often severe complication in diabetes mellitus. Hyperglycemia and hypertension are considered to be two of the leading risk factors for vascular complications in diabetic patients. However, few pharmacologi
Autor:
Jin Ma, Yue Cai, Zhongchao Wang, Jin-Wen Yu, Jun-Xiang Bao, Qiang Lv, Yao-Ping Cheng, Huan Liu, Yue Wu, Yu-Ting Su, Yun-Gang Bai
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 3, Pp 1013-1024 (2017)
Background/Aims: High concentration of bile acids (BAs) induces hydrophobicity-dependent vasorelaxtant effects with hydrophobic BAs showing greater responses than hydrophilic BAs, of which the underlying mechanisms are still unclear. Caveolae are inv