Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Yun-Feng, Li"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionMajor depressive disorder (MDD) is a common and disabling mental health condition; the currently available treatments for MDD are insufficient to meet clinical needs due to their limited efficacy and slow onset of action. Hypidone hydroch
Externí odkaz:
https://doaj.org/article/78402d27e0a14a49aabd4d669dd6c202
Autor:
Xiao-Qiong Chen, Xuan Zhang, Ding-Guo Pan, Guo-Yu Li, Rui-Xi Hu, Tao Wu, Tao Shen, Xin-Yi Cai, Xian-Shuo Cheng, Junying Qin, Fu-Hui Xiao, Yun-Feng Li
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33738- (2024)
Background: Colon adenocarcinoma (COAD) is one of the most common malignant tumors. The interplay involving ferroptosis between tumor and immune cells plays a crucial in cancer progression. However, the biological basis of this interplay in COAD deve
Externí odkaz:
https://doaj.org/article/e5714de55d374368a3e9e6d1f2670eb7
Autor:
Zeina Salloum, Kristin Dauner, Yun-feng Li, Neha Verma, David Valdivieso-González, Víctor Almendro-Vedia, John D Zhang, Kiran Nakka, Mei Xi Chen, Jeffrey McDonald, Chase D Corley, Alexander Sorisky, Bao-Liang Song, Iván López-Montero, Jie Luo, Jeffrey F Dilworth, Xiaohui Zha
Publikováno v:
eLife, Vol 13 (2024)
Statins are known to be anti-inflammatory, but the mechanism remains poorly understood. Here, we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol levels and higher expression of Jmjd3, a
Externí odkaz:
https://doaj.org/article/ed7269abf3734a6fbbad42dc2661c083
Autor:
Xiao-Qiong Chen, Ke Lian, Zi-Wei Chen, Xuan Zhang, Ting Li, Tao Wu, Tao Shen, Xin-Yi Cai, Xian-Shuo Cheng, Fu-Hui Xiao, Yun-Feng Li
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 13 (2024)
Background: Ferroptosis, an iron-dependent form of cell death, plays a crucial role in the progression of various cancers, including colon adenocarcinoma (COAD). However, the multi-omics signatures relevant to ferroptosis regulation in COAD diagnosis
Externí odkaz:
https://doaj.org/article/9605e55e597e44168cf84a252b728f4b
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/b65faa49f6a742f48a58d374312b394d
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Intracerebral microglia play a vital role in mediating central immune response, neuronal repair and synaptic pruning, but its precise role and mechanism in fast action of antidepressants have remained unknown. In this study, we identifi
Externí odkaz:
https://doaj.org/article/945acbdbae554d82b71642c68336673e
Autor:
Yong-Yu Yin, Zhao-Kai Lai, Jiao- Zhao Yan, Qian-Qian Wei, Bin Wang, Li-Ming Zhang, Yun-Feng Li
Publikováno v:
Neurobiology of Stress, Vol 24, Iss , Pp 100536- (2023)
Social hierarchy greatly impacts physical and mental health, but the relationship between social hierarchy and depression/anxiety and the underlying neural mechanism remain unclear. The present study used the tube test to determine the social hierarc
Externí odkaz:
https://doaj.org/article/28512b61f762465bb18e3d2151a1c247
Publikováno v:
Journal of Integrative Agriculture, Vol 21, Iss 4, Pp 1188-1202 (2022)
Domestication and genetic improvement of maize improve yield and stress tolerance due to changes in morphological and physiological properties, which likely alter rhizosphere microbial diversity. Understanding how the evolution of maize germplasm imp
Externí odkaz:
https://doaj.org/article/aeae5e31e0f94d2ea37aaf4756358502
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Major depression disorder (MDD) is a common and potentially life-threatening mental illness; however, data on its pathogenesis and effective therapeutic measures are lacking. Pathological changes in astrocytes play a pivotal role in MDD
Externí odkaz:
https://doaj.org/article/4e3c0c4cb24d48ffa6e994fa40643890
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Aging is a major risk factor for cancer development. As dysfunction in protein homeostasis, or proteostasis, is a universal hallmark of both the aging process and cancer, a comprehensive understanding of the proteostasis system and its roles in aging
Externí odkaz:
https://doaj.org/article/e251097c1af04747ba3adb6ef56ad682