Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Yun-Fai Chris Lau"'
Autor:
Tatsuo Kido, Yun-Fai Chris Lau
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-9 (2023)
Abstract Androgen receptor variant 7 (AR-V7), an AR isoform with a truncated ligand-binding domain, functions as a transcription factor in an androgen-independent manner. AR-V7 is expressed in a subpopulation of hepatocellular carcinoma (HCC), howeve
Externí odkaz:
https://doaj.org/article/6328bcd0ba934f04a0e2892e682c1203
Autor:
Yun-Fai Chris Lau
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Sex differences are prevalent in normal development, physiology and disease pathogeneses. Recent studies have demonstrated that mosaic loss of Y chromosome and aberrant activation of its genes could modify the disease processes in male biase
Externí odkaz:
https://doaj.org/article/728a27029c57478d8ce05b20d747c0e4
Autor:
Tatsuo Kido, Yun-Fai Chris Lau
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Background Liver cancer is one of the major causes of cancer death worldwide, with significantly higher incidence and mortality among the male patients. Although sex hormones and their receptors could contribute to such sex differences, the
Externí odkaz:
https://doaj.org/article/9f6e9c8251b244138fe1d99e3a925ad8
Autor:
Yun-Fai Chris Lau
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-1 (2021)
Abstract Three articles published by the research groups led by Yun-Bo Shi of the National Institute of Child Health and Human Development, National Institutes of Health, USA; Aria Baniahmad of the Institute of Human Genetics, Jena University Hospita
Externí odkaz:
https://doaj.org/article/806e2575d82c4dea9a46740edd7cd75f
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Sexual dimorphisms are prevalent in development, physiology and diseases in humans. Currently, the contributions of the genes on the male-specific region of the Y chromosome (MSY) in these processes are uncertain. Using a transgene activatio
Externí odkaz:
https://doaj.org/article/41ff5c0cb38e41218f0c9cb9f402d29c
Autor:
Yun-Fai Chris Lau
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-2 (2020)
Abstract Two articles published by the research groups led by You-Shuo Liu of the Central South University, Changsha, Hunan, and Min Fang of the Huazhong University of Science and Technology, Wuhan, China have been selected as the recipients of the 2
Externí odkaz:
https://doaj.org/article/79e8697ee7634249b0c8bd0683666d5f
Autor:
Tatsuo Kido, Yun-Fai Chris Lau
Publikováno v:
Asian Journal of Andrology, Vol 17, Iss 3, Pp 373-380 (2015)
Male and female differ genetically by their respective sex chromosome composition, that is, XY as male and XX as female. Although both X and Y chromosomes evolved from the same ancestor pair of autosomes, the Y chromosome harbors male-specific genes,
Externí odkaz:
https://doaj.org/article/6a599cdd850f48c1a02b588cef406144
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 723-733 (2014)
Male sex determination is mediated sequentially by sex-determining region Y (SRY) and related SRY-box 9 (SOX9) transcription factors. To understand the gene regulatory hierarchy for SRY and SOX9, a series of chromatin immunoprecipitation and whole-ge
Externí odkaz:
https://doaj.org/article/cda3263e14014174bb665429fd4d7e80
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22979 (2011)
Hepatitis B virus (HBV) infection is a major risk for hepatocellular carcinoma (HCC), and it is a serious global health problem with two billion people exposed to it worldwide. HBx, an essential factor for viral replication and a putative oncoprotein
Externí odkaz:
https://doaj.org/article/66dd85817b894208a4f20cbabb88337b
Publikováno v:
Cancer Science
Hepatocellular carcinoma (HCC) is a highly heterogeneous liver cancer with significant male biases in incidence, disease progression, and outcomes. Previous studies have suggested that genes on the Y chromosome could be expressed and exert various ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c89abbd21c506b03848079ee4e8535
https://doi.org/10.1111/cas.14506
https://doi.org/10.1111/cas.14506