Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Yun-Chi Lu"'
Autor:
Wen-Wei Lin, Yun-Chi Lu, Bo-Cheng Huang, Chih-Hung Chuang, Yi-An Cheng, I.-Ju Chen, Hui-Ju Liu, Kai-Wen Ho, Tzu-Yi Liao, En-Shuo Liu, Ting-Yi Wu, Long-Sen Chang, Shih-Ting Hong, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Canakinumab is a fully human monoclonal antibody that specifically neutralizes human interleukin (IL)-1β and has been approved by the US Food and Drug Administration for treating different types of autoinflammatory disorders such as cryopyr
Externí odkaz:
https://doaj.org/article/cbc2120056d34be588820d88d63a8a3e
Autor:
Wen-Wei Lin, Yi-An Cheng, Chia-Ching Li, Kai-Wen Ho, Huei-Jen Chen, I.-J.u Chen, Bo-Cheng Huang, Hui-Ju Liu, Yun-Chi Lu, Chiu-Min Cheng, Ming-Yii Huang, Hung-Wen Lai, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby elim
Externí odkaz:
https://doaj.org/article/63d97e87db234af79d3c1e4526c6bbd3
Autor:
Kai-Wen Ho, I.-J.u Chen, Yi-An Cheng, Tzu-Yi Liao, En-Shuo Liu, Huei-Jen Chen, Yun-Chi Lu, Yu-Cheng Su, Steve R. Roffler, Bo-Cheng Huang, Hui-Ju Liu, Ming-Yii Huang, Chiao-Yun Chen, Tian-Lu Cheng
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization. Methods In this s
Externí odkaz:
https://doaj.org/article/90203a981820425d90aa6193a4e80d5c
Autor:
Yi-An Cheng, Tung-Ho Wu, Yun-Ming Wang, Tian-Lu Cheng, I-Ju Chen, Yun-Chi Lu, Kuo-Hsiang Chuang, Chih-Kuang Wang, Chiao-Yun Chen, Rui-An Lin, Huei-Jen Chen, Tzu-Yi Liao, En-Shuo Liu, Fang-Ming Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Developing a universal strategy to improve the specificity and sensitivity of PEGylated nanoaparticles (PEG-NPs) for assisting in the diagnosis of tumors is important in multimodality imaging. Here, we developed the anti-methoxypo
Externí odkaz:
https://doaj.org/article/a1709e686d1b41b7aed8c1d16fb3348b
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-20 (2020)
Abstract Monoclonal antibodies (mAbs) are a major targeted therapy for malignancies, infectious diseases, autoimmune diseases, transplant rejection and chronic inflammatory diseases due to their antigen specificity and longer half-life than conventio
Externí odkaz:
https://doaj.org/article/683231de7fa74837b659cda00e6f7b17
Autor:
Wen-Wei Lin, Kai-Wen Ho, Hsiang-Han Su, Tien-Fang Fang, Shey-Cherng Tzou, I-Ju Chen, Yun-Chi Lu, Mu-Shen Chang, Yun-Chen Tsai, En-Shuo Liu, Yu-Cheng Su, Yen-Tseng Wang, Tian-Lu Cheng, Hsin-Kai Huang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Fibrinogen-like protein 1 (FGL1) was recently identified as a major ligand of lymphocyte-activation gene-3 (LAG-3) on activated T cells and serves as an immune suppressive molecule for regulation of immune homeostasis. However, whether FGL1 has thera
Externí odkaz:
https://doaj.org/article/2f22afbac68e419987c354eef80b6a3e
Autor:
Yun-Chi Lu, Chih-Hung Chuang, Kuo-Hsiang Chuang, I-Ju Chen, Bo-Cheng Huang, Wen-Han Lee, Hsin-Ell Wang, Jia-Je Li, Yi-An Cheng, Kai-Wen Cheng, Jaw-Yuan Wang, Yuan-Chin Hsieh, Wen-Wei Lin, Tian-Lu Cheng
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000286 (2019)
During rheumatoid arthritis (RA) treatment, long-term injection of antitumor necrosis factor α antibodies (anti-TNFα Abs) may induce on-target toxicities, including severe infections (tuberculosis [TB] or septic arthritis) and malignancy. Here, we
Externí odkaz:
https://doaj.org/article/39db0cdbd8aa45ea8f35056529c673f5
Autor:
Chia-Ching Li, Chiu-Min Cheng, Yun-Chi Lu, Hung-Wen Lai, Kai-Wen Ho, I-Ju Chen, Yi-An Cheng, Ming-Yii Huang, Huei-Jen Chen, Hui-Ju Liu, Bo-Cheng Huang, Wen-Wei Lin, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby eliminating r
Autor:
Tian-Lu Cheng, I-Ju Chen, Yun Chi Lu, Yu-Cheng Su, Tzu Yi Liao, Yi An Cheng, Ming-Yii Huang, Kai Wen Ho, Steve R. Roffler, Huei Jen Chen, En Shuo Liu, Chiao Yun Chen, Hui Ju Liu, Bo Cheng Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization. Methods In this study, we
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-20 (2020)
Journal of Biomedical Science
Journal of Biomedical Science
Monoclonal antibodies (mAbs) are a major targeted therapy for malignancies, infectious diseases, autoimmune diseases, transplant rejection and chronic inflammatory diseases due to their antigen specificity and longer half-life than conventional drugs