Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yun-An A. Shen"'
Autor:
Kimberle Shen, Mike Reichelt, Roxanne V. Kyauk, Hai Ngu, Yun-An A. Shen, Oded Foreman, Zora Modrusan, Brad A. Friedman, Morgan Sheng, Tracy J. Yuen
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108835- (2021)
Summary: In multiple sclerosis (MS) and other neurological diseases, the failure to repair demyelinated lesions contributes to axonal damage and clinical disability. Here, we provide evidence that Mertk, a gene highly expressed by microglia that alte
Externí odkaz:
https://doaj.org/article/9d23f8d6e57c4fce98cb7a14633a0b45
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 544-550.e3 (2018)
Summary: Emerging evidence suggests that neuronal signaling is important for oligodendrocyte myelination; however, the necessity of this signaling during development is unclear. By eliminating dynamic neuronal signaling along the developing optic ner
Externí odkaz:
https://doaj.org/article/ec720413336e43cb82181c0a126042fd
Autor:
Fei YIN, Yun LIU, Xie SHEN
Publikováno v:
Zhongguo quanke yixue, Vol 25, Iss 20, Pp 2498-2506 (2022)
Background Severe multiple trauma prevalence has been increasing recently, which has become the leading cause of labor force loss. Early and rapid assessment of patients' conditions will greatly affect their prognosis, which could be significantly su
Externí odkaz:
https://doaj.org/article/0574d11287484755b59fa80f735c4038
Autor:
Yuanyuan Wang, Roxanne V. Kyauk, Yun‐An A. Shen, Luke Xie, Mike Reichelt, Han Lin, Zhiyu Jiang, Hai Ngu, Kimberle Shen, Jacob J. Greene, Morgan Sheng, Tracy J. Yuen
Publikováno v:
Glia. 71:1247-1258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::310826d1052d34aaa1e36c1075bfb9f7
https://doi.org/10.1002/glia.24335
https://doi.org/10.1002/glia.24335
Autor:
Feng Mei, Klaus Lehmann-Horn, Yun-An A Shen, Kelsey A Rankin, Karin J Stebbins, Daniel S Lorrain, Kara Pekarek, Sharon A Sagan, Lan Xiao, Cory Teuscher, H-Christian von Büdingen, Jürgen Wess, J Josh Lawrence, Ari J Green, Stephen PJ Fancy, Scott S Zamvil, Jonah R Chan
Publikováno v:
eLife, Vol 5 (2016)
Demyelination in MS disrupts nerve signals and contributes to axon degeneration. While remyelination promises to restore lost function, it remains unclear whether remyelination will prevent axonal loss. Inflammatory demyelination is accompanied by si
Externí odkaz:
https://doaj.org/article/4da806c40b4949a2851d1bc03be524f7
Autor:
YUN, LISA LI-SHEN
Publikováno v:
Caribbean Quarterly, 2004 Jun 01. 50(2), 26-43.
Externí odkaz:
https://www.jstor.org/stable/40654451
Autor:
Shristi Pandey, Kimberle Shen, Seung-Hye Lee, Yun-An A. Shen, Yuanyuan Wang, Marcos Otero-García, Natalya Kotova, Stephen T. Vito, Benjamin I. Laufer, Dwight F. Newton, Mitchell G. Rezzonico, Jesse E. Hanson, Joshua S. Kaminker, Christopher J. Bohlen, Tracy J. Yuen, Brad A. Friedman
Publikováno v:
Cell Reports. 40:111189
Oligodendrocyte dysfunction has been implicated in the pathogenesis of neurodegenerative diseases, so understanding oligodendrocyte activation states would shed light on disease processes. We identify three distinct activation states of oligodendrocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d468c3ee18ff004b00fa74d78b995d6
https://doi.org/10.1016/j.celrep.2022.111189
https://doi.org/10.1016/j.celrep.2022.111189
Autor:
Mike Reichelt, Oded Foreman, Roxanne V. Kyauk, Hai Ngu, Brad A. Friedman, Yun-An A. Shen, Tracy J. Yuen, Zora Modrusan, Morgan Sheng, Kimberle Shen
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108835-(2021)
Summary: In multiple sclerosis (MS) and other neurological diseases, the failure to repair demyelinated lesions contributes to axonal damage and clinical disability. Here, we provide evidence that Mertk, a gene highly expressed by microglia that alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b283c43f708bbc42e2107769e7437b4
http://www.sciencedirect.com/science/article/pii/S2211124721001492
http://www.sciencedirect.com/science/article/pii/S2211124721001492
Autor:
Daniel S. Lorrain, Jonah R. Chan, Kelsey Rankin, Sonia R. Mayoral, Ari J. Green, Sergio E. Baranzini, Riley Bove, Kicheol Kim, Yun-An A Shen, Caroline Desponts, Feng Mei
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 39, iss 12
A significant unmet need for patients with multiple sclerosis (MS) is the lack of U.S. Food and Drug Administration (FDA)-approved remyelinating therapies. We have identified a compelling remyelinating agent, bazedoxifene (BZA), a European Medicines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e38e0b220e3bf6b8bb019244ca101d2
https://escholarship.org/uc/item/969099jq
https://escholarship.org/uc/item/969099jq
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1791
Myelination necessitates axons to initiate concentric membrane wrapping by oligodendroglia in the CNS. Here, we describe an in vitro system that models CNS myelination with a minimally permissive environment, termed Binary Indicant for myelination us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a2309cf390c73be0528235277e00aab
https://pubmed.ncbi.nlm.nih.gov/30006709
https://pubmed.ncbi.nlm.nih.gov/30006709