Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Yun William Yu"'
Autor:
Spouge JL; Intramural Research Program, National Library of Medicine, Bethesda, MD 20894, USA.
Publikováno v:
Bioinformatics (Oxford, England) [Bioinformatics] 2022 Oct 14; Vol. 38 (20), pp. 4848-4849.
Autor:
Jim Shaw, Yun William Yu
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background Metagenomic binning, the clustering of assembled contigs that belong to the same genome, is a crucial step for recovering metagenome-assembled genomes (MAGs). Contigs are linked by exploiting consistent signatures along a genome,
Externí odkaz:
https://doaj.org/article/f77300fb0b224c038718c4e822d9351d
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Taxonomic classification of reads obtained by metagenomic sequencing is often a first step for understanding a microbial community, but correctly assigning sequencing reads to the strain or sub-species level has remained a challen
Externí odkaz:
https://doaj.org/article/49cab98897c847afb0115ea04022830f
Autor:
John Spouge
Publikováno v:
Bioinformatics
Selecting a subset of k-mers in a string in a local manner is a common task in bioinformatics tools for speeding up computation. Arguably the most well-known and common method is the minimizer technique, which selects the 'lowest-ordered' k-mer in a
Autor:
Luke Staniscia, Yun William Yu
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Because of the rapid generation of data, the study of compression algorithms to reduce storage and transmission costs is important to bioinformaticians. Much of the focus has been on sequence data, including both genomes and prote
Externí odkaz:
https://doaj.org/article/740ecc683de3448d924fa0cbb51d4a5a
Autor:
Spouge, John L1 (AUTHOR) spouge@nih.gov
Publikováno v:
Bioinformatics. 10/15/2022, Vol. 38 Issue 20, p4848-4849. 2p.
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Microbial populations exhibit functional changes in response to different ambient environments. Although whole metagenome sequencing promises enough raw data to study those changes, existing tools are limited in their ability to directly com
Externí odkaz:
https://doaj.org/article/d49f622598864a3f8a82270729879f28
Autor:
Bonnie Berger, Yun William Yu
Publikováno v:
Nat Rev Genet
Genome sequencing and analysis allow researchers to decode the functional information hidden in DNA sequences as well as to study cell to cell variation within a cell population. Traditionally, the primary bottleneck in genomic analysis pipelines has
Autor:
Yun William Yu, Jim Shaw
Publikováno v:
Journal of Computational Biology. 29:195-211
Resolving haplotypes in polyploid genomes using phase information from sequencing reads is an important and challenging problem. We introduce two new mathematical formulations of polyploid haplotype phasing: (1) the min-sum max tree partition problem
Autor:
Yun William Yu, Jim Shaw
Publikováno v:
Bioinformatics. 38:4659-4669
Motivation Selecting a subset of k-mers in a string in a local manner is a common task in bioinformatics tools for speeding up computation. Arguably the most well-known and common method is the minimizer technique, which selects the ‘lowest-ordered