Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Yun Ti Chen"'
Autor:
Yun-Ti Chen, Jinhui Li, Jen-Ning Chang, Yong-Chun Luo, Wuyue Yu, Lung-Chi Chen, Jinn-Moon Yang
Publikováno v:
Environment International, Vol 177, Iss , Pp 108027- (2023)
Over 400,000 people are estimated to have been exposed to World Trade Center particulate matter (WTCPM) since the attack on the Twin Towers in Lower Manhattan on September 11, 2001. Epidemiological studies have found that exposure to dust may cause r
Externí odkaz:
https://doaj.org/article/a8ce409e572f49f388f943a9f3479204
Autor:
Xiang-Yu Lin, Yu-Wei Huang, You-Wei Fan, Yun-Ti Chen, Nikhil Pathak, Yen-Chao Hsu, Jinn-Moon Yang
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S4, Pp 1-13 (2022)
Abstract Background Human protein kinases, the key players in phosphoryl signal transduction, have been actively investigated as drug targets for complex diseases such as cancer, immune disorders, and Alzheimer’s disease, with more than 60 successf
Externí odkaz:
https://doaj.org/article/df07a3ef2fba48bf879af1badd82978c
Autor:
You-Wei Fan, Wan-Hsin Liu, Yun-Ti Chen, Yen-Chao Hsu, Nikhil Pathak, Yu-Wei Huang, Jinn-Moon Yang
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S4, Pp 1-17 (2022)
Abstract Background While it has been known that human protein kinases mediate most signal transductions in cells and their dysfunction can result in inflammatory diseases and cancers, it remains a challenge to find effective kinase inhibitor as drug
Externí odkaz:
https://doaj.org/article/e537cc754f024ceeb96fda93cc9b5961
Autor:
Yu-Wei Huang, Yen-Chao Hsu, Yi-Hsuan Chuang, Yun-Ti Chen, Xiang-Yu Lin, You-Wei Fan, Nikhil Pathak, Jinn-Moon Yang
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S4, Pp 1-13 (2022)
Abstract Background Human protein kinases play important roles in cancers, are highly co-regulated by kinase families rather than a single kinase, and complementarily regulate signaling pathways. Even though there are > 100,000 protein kinase inhibit
Externí odkaz:
https://doaj.org/article/82a0cd673e1d49fdabb77c7a5444370a
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Protein kinase-inhibitor interactions are key to the phosphorylation of proteins involved in cell proliferation, differentiation, and apoptosis, which shows the importance of binding mechanism research and kinase inhibitor design. In this st
Externí odkaz:
https://doaj.org/article/aa489f0f47934d49b343e21f286e90cb
Autor:
Yun-Ti Chen, Yu-Hsiu Chang, Nikhil Pathak, Shey-Cherng Tzou, Yong-Chun Luo, Yen-Chao Hsu, Tian-Neng Li, Jung-Yu Lee, Yi-Cyun Chen, Yu-Wei Huang, Hsin-Ju Yang, Nung-Yu Hsu, Hui-Ping Tsai, Tein-Yao Chang, Shu-Chen Hsu, Ping-Cheng Liu, Yuan-Fan Chin, Wen-Chin Lin, Chuen-Mi Yang, Hsueh-Ling Wu, Chia-Ying Lee, Hui-Ling Hsu, Yi-Chun Liu, Jhih-Wei Chu, Lily Hui-Ching Wang, Jann-Yuan Wang, Chih-Heng Huang, Chi-Hung Lin, Po-Shiuan Hsieh, Yan-Hwa Wu Lee, Yi-Jen Hung, Jinn-Moon Yang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDrug repurposing is a fast and effective way to develop drugs for an emerging disease such as COVID-19. The main challenges of effective drug repurposing are the discoveries of the right therapeutic targets and the right drugs for combating
Externí odkaz:
https://doaj.org/article/e0d9b744dc564e78affee0cda9c37a2a
Autor:
Wei-Chung Chiou, Meng-Shiuan Hsu, Yun-Ti Chen, Jinn-Moon Yang, Yeou-Guang Tsay, Hsiu-Chen Huang, Cheng Huang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 147-153 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19). Since its emergence, the COVID-19 pandemic has not only distressed medical services but also caused economic upheavals, marking urgen
Externí odkaz:
https://doaj.org/article/26dcef64fb0d4fa0822e163bcbe9f3a1
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14958 (2022)
Autoimmune hypophysitis (AH) is an autoimmune disease of the pituitary for which the pathogenesis is incompletely known. AH is often treated with corticosteroids; however, steroids may lead to considerable side effects. Using a mouse model of AH (exp
Externí odkaz:
https://doaj.org/article/4bd6430dd0434c469707e91f6b5618a5
Autor:
Chien‐Chin Lee, Wen‐Hsin Chang, Ya‐Sian Chang, Jinn‐Moon Yang, Chih‐Shiang Chang, Kai‐Cheng Hsu, Yun‐Ti Chen, Ting‐Yuan Liu, Yu‐Chia Chen, Shyr‐Yi Lin, Yang‐Chang Wu, Jan‐Gowth Chang
Publikováno v:
Molecular Oncology, Vol 13, Iss 8, Pp 1744-1762 (2019)
Alternative splicing (AS) is a process that enables the generation of multiple protein isoforms with different biological properties from a single mRNA. Cancer cells often use the maneuverability conferred by AS to produce proteins that contribute to
Externí odkaz:
https://doaj.org/article/3700c3880d7a404398b4825c427c67e3
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