Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Yun Soo Bae"'
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Background Various renal abnormalities, including hydronephrosis, polycystic kidney disease, and hydroureter, have been reported, and these abnormalities are present in DiGeorge syndrome, renal dysplasia, and acute kidney failure. Previous s
Externí odkaz:
https://doaj.org/article/711387bd49894e70ba952d8f56924c98
Autor:
Sae Rom Lee, Hye Eun Lee, Jung-Yeon Yoo, Eun Jung An, Soo-Jin Song, Ki-Hwan Han, Dae Ryong Cha, Yun Soo Bae
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108868- (2024)
Summary: Nox4-derived H2O2 generation plays an important role in the pathogenesis of chronic kidney diseases (CKDs) such as diabetic nephropathy (DN). Here, we showed that SH3 domain-containing Ysc84-like 1 (SH3YL1), a Nox4 cytosolic activator, regul
Externí odkaz:
https://doaj.org/article/b4a1e488d3bf452e968bb23c2e9e9a5e
Autor:
Jung Min Suh, Yelin Son, Jung-Yeon Yoo, Yookyung Goh, Nabil G. Seidah, Sanghyuk Lee, Yun Soo Bae
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 993-1001 (2021)
Previously we demonstrated that Ahnak mediates transforming growth factor-β (TGFβ)-induced epithelial-mesenchymal transition (EMT) during tumor metastasis. It is well-known that circulating tumor cells (CTCs) invade the vasculature of adjacent targ
Externí odkaz:
https://doaj.org/article/2b988243c48b4ad689afc2b674a14241
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss Suppl 2, Pp S89-S98 (2022)
Oxidative stress can cause generation of uncontrolled reactive oxygen species (ROS) and lead to cytotoxic damage to cells and tissues. Recently, it has been shown that transient ROS generation can serve as a secondary messenger in receptor-mediated c
Externí odkaz:
https://doaj.org/article/bf22b146cb1d4f818ac05e7ce90e5f9f
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 7, Pp 1-13 (2019)
Atherosclerosis: halting plaque in its tracks TLR5-Nox4 signaling cascade plays a key role in atherosclerosis, hardening of the arteries, in which fatty deposits known as plaques accumulate in the inner walls of arteries. During plaque formation, vas
Externí odkaz:
https://doaj.org/article/a0760d51853741c38b1b21d17ef4c874
Autor:
Siddhartha Kumar Mishra, Yun Soo Bae, Yong-Moon Lee, Jae-Sung Kim, Seung Hyun Oh, Hwan Mook Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Chemosensitization of cancer cells with small molecules may improve the therapeutic index of antitumoral agents by making tumor cells sensitive to the drug regimen and thus overcome the treatment resistance and side effects of single therapy. Cell me
Externí odkaz:
https://doaj.org/article/ba96674a908148b9b49932c3b7d220a1
Autor:
Jung-Yeon Yoo, Dae Ryong Cha, Borim Kim, Eun Jung An, Sae Rom Lee, Jin Joo Cha, Young Sun Kang, Jung Yeon Ghee, Jee Young Han, Yun Soo Bae
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108245- (2020)
Summary: Cytosolic proteins are required for regulation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (Nox) isozymes. Here we show that Src homology 3 (SH3) domain-containing YSC84-like 1 (SH3YL1), as a Nox4 cytosolic regulator, medi
Externí odkaz:
https://doaj.org/article/c4db8bbe17f14753bfe684222bc94359
Autor:
Sarah A. Woller, Soo-Ho Choi, Eun Jung An, Hann Low, Dina A. Schneider, Roshni Ramachandran, Jungsu Kim, Yun Soo Bae, Dmitri Sviridov, Maripat Corr, Tony L. Yaksh, Yury I. Miller
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2667-2677 (2018)
Apolipoprotein A-I binding protein (AIBP) reduces lipid raft abundance by augmenting the removal of excess cholesterol from the plasma membrane. Here, we report that AIBP prevents and reverses processes associated with neuroinflammatory-mediated spin
Externí odkaz:
https://doaj.org/article/752f1381fb2546bd8b718014a285dc72
Autor:
Ji Hye Kim, Jina Lee, Su-Jin Bae, Yeeun Kim, Byung-Joon Park, Jae-Won Choi, Jaeyul Kwon, Guang-Ho Cha, Heon Jong Yoo, Eun-Kyeong Jo, Yun Soo Bae, Young-Ha Lee, Jae-Min Yuk
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are an important family of catalytic enzymes that generate reactive oxygen species (ROS), which mediate the regulation of diverse cellular functions. Although phagocyte Nox2/
Externí odkaz:
https://doaj.org/article/4283dbd78b614c17a4ad3a03b5ead2b0
Publikováno v:
Pharmaceutics, Vol 11, Iss 9, p 482 (2019)
In a previous study, the specific NOX1/2/4 inhibitor Ewha-18278 was confirmed as a possible treatment for osteoporosis both in vitro and in vivo. Here, we investigated the pharmacokinetics (PK) of the compound by intravenous (IV) and oral administrat
Externí odkaz:
https://doaj.org/article/747046da6e5c44798e8ace5f6122abcf