Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yun Rose Li"'
Autor:
Yun Rose Li, Joseph T. Glessner, Bradley P. Coe, Jin Li, Maede Mohebnasab, Xiao Chang, John Connolly, Charlly Kao, Zhi Wei, Jonathan Bradfield, Cecilia Kim, Cuiping Hou, Munir Khan, Frank Mentch, Haijun Qiu, Marina Bakay, Christopher Cardinale, Maria Lemma, Debra Abrams, Andrew Bridglall-Jhingoor, Meckenzie Behr, Shanell Harrison, George Otieno, Alexandria Thomas, Fengxiang Wang, Rosetta Chiavacci, Lawrence Wu, Dexter Hadley, Elizabeth Goldmuntz, Josephine Elia, John Maris, Robert Grundmeier, Marcella Devoto, Brendan Keating, Michael March, Renata Pellagrino, Struan F. A. Grant, Patrick M. A. Sleiman, Mingyao Li, Evan E. Eichler, Hakon Hakonarson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Associations of copy number variations (CNVs) with complex traits are challenging to study because of their low frequency. Here, the authors analyse SNP array and array comparative genomic hybridization data of 100,028 individuals and report their as
Externí odkaz:
https://doaj.org/article/bff05ccd6ca145f18966c6e073fcf8bb
Autor:
Yun Rose Li, Kyle D. Halliwill, Cassandra J. Adams, Vivek Iyer, Laura Riva, Rashid Mamunur, Kuang-Yu Jen, Reyno del Rosario, Erik Fredlund, Gillian Hirst, Ludmil B. Alexandrov, David Adams, Allan Balmain
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation.
Externí odkaz:
https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd4
Autor:
Hitoshi Kida, Yosuke Fukutani, Joel D. Mainland, Claire A. de March, Aashutosh Vihani, Yun Rose Li, Qiuyi Chi, Akemi Toyama, Linda Liu, Masaharu Kameda, Masafumi Yohda, Hiroaki Matsunami
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Biomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sens
Externí odkaz:
https://doaj.org/article/4bb70edca5cc4c01907d20a917e26727
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Immune checkpoint inhibitors targeting PD-1 and PD-L1 have demonstrated anti-tumor activity in several advanced solid malignancies. In previously treated metastatic castration resistant prostate cancer (mCRPC), a small subset of patients have a thera
Externí odkaz:
https://doaj.org/article/80871f0d1b744f7e94aedb7cb2b6adbb
Autor:
Gijs van Ingen, Jin Li, André Goedegebure, Rahul Pandey, Yun Rose Li, Michael E. March, Vincent W. V. Jaddoe, Marina Bakay, Frank D. Mentch, Kelly Thomas, Zhi Wei, Xiao Chang, Heather S. Hain, André G. Uitterlinden, Henriette A. Moll, Cornelia M. van Duijn, Fernando Rivadeneira, Hein Raat, Robert J. Baatenburg de Jong, Patrick M. Sleiman, Marc P. van der Schroeff, Hakon Hakonarson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Acute otitis media (AOM) is an acute infection of middle ear mucosa and among the most common pediatric diseases. Here, the authors performed a genome-wide association study to link a variant in the FNDC1 locus on 6q25.3 and differential methylation
Externí odkaz:
https://doaj.org/article/5e841bd590864ecca71796318ebd7c9f
Autor:
Che-Pei Kung, Meghan B Skiba, Erika J Crosby, Jessica Gorzelitz, Mary A Kennedy, Bethany A Kerr, Yun Rose Li, Sarah Nash, Melanie Potiaumpai, Amber S Kleckner, Dara L James, Michael F Coleman, Ciaran M Fairman, Gloria C Galván, David O Garcia, Max J Gordon, Mathilde His, Lyndsey M Hornbuckle, So-Youn Kim, Tae-Hyung Kim, Amanika Kumar, Mélanie Mahé, Karen K McDonnell, Jade Moore, Sangphil Oh, Xinghui Sun, Melinda L Irwin
Publikováno v:
JNCI Monographs. 2023:149-157
The overall goal of the annual Transdisciplinary Research in Energetics and Cancer (TREC) Training Workshop is to provide transdisciplinary training for scientists in energetics and cancer and clinical care. The 2022 Workshop included 27 early-to-mid
Autor:
Faiza Kalam, Dara L James, Yun Rose Li, Michael F Coleman, Violet A Kiesel, Elizabeth M Cespedes Feliciano, Stephen D Hursting, Dorothy D Sears, Amber S Kleckner
Publikováno v:
JNCI Monographs. 2023:84-103
Intermittent fasting entails restricting food intake during specific times of day, days of the week, religious practice, or surrounding clinically important events. Herein, the metabolic and circadian rhythm mechanisms underlying the proposed benefit
Autor:
Brian D. Piening, Alexa K. Dowdell, Mengqi Zhang, Bao-Li Loza, David Walls, Hui Gao, Maede Mohebnasab, Yun Rose Li, Eric Elftmann, Eric Wei, Divya Gandla, Hetal Lad, Hassan Chaib, Nancy K. Sweitzer, Mario Deng, Alexandre C. Pereira, Martin Cadeiras, Abraham Shaked, Michael P. Snyder, Brendan J. Keating
Publikováno v:
J Heart Lung Transplant
BACKGROUND: Heart transplantation provides a significant improvement in survival and quality of life for patients with end-stage heart disease, however many recipients experience different levels of graft rejection that can be associated with signifi
Autor:
Mark A. Taylor, Eve Kandyba, Kyle Halliwill, Reyno Delrosario, Matvei Koroshkin, Hani Goodarzi, David Quigley, Yun Rose Li, Di Wu, Saumya Bollam, Olga Mirzoeva, Rosemary J. Akhurst, Allan Balmain
Adult mammalian stem cells play critical roles in normal tissue homeostasis, as well as in tumor development, by contributing to cell heterogeneity, plasticity, and development of drug resistance. The relationship between different types of normal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce948eb8a49d3314c422f3a2d5bd0da6
https://doi.org/10.1101/2023.05.08.539863
https://doi.org/10.1101/2023.05.08.539863
Autor:
S.M. Ashiqul Islam, Marcos Díaz-Gay, Yang Wu, Mark Barnes, Raviteja Vangara, Erik N. Bergstrom, Yudou He, Mike Vella, Jingwei Wang, Jon W. Teague, Peter Clapham, Sarah Moody, Sergey Senkin, Yun Rose Li, Laura Riva, Tongwu Zhang, Andreas J. Gruber, Christopher D. Steele, Burçak Otlu, Azhar Khandekar, Ammal Abbasi, Laura Humphreys, Natalia Syulyukina, Samuel W. Brady, Boian S. Alexandrov, Nischalan Pillay, Jinghui Zhang, David J. Adams, Iñigo Martincorena, David C. Wedge, Maria Teresa Landi, Paul Brennan, Michael R. Stratton, Steven G. Rozen, Ludmil B. Alexandrov
Publikováno v:
Cell genomics, vol 2, iss 11
Mutational signature analysis is commonly performed in cancer genomic studies. Here, we present SigProfilerExtractor, an automated tool for de novo extraction of mutational signatures, and benchmark it against another 13 bioinformatics tools by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66650f68920d43fde2ce688d861fe80
https://escholarship.org/uc/item/9b82739r
https://escholarship.org/uc/item/9b82739r