Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yun L. Ma"'
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-20 (2017)
Abstract Background Smad4 is a critical effector of TGF-β signaling that regulates a variety of cellular functions. However, its role in the brain has rarely been studied. Here, we examined the molecular mechanisms underlying the post-translational
Externí odkaz:
https://doaj.org/article/b2ba92ad622f4202ae49e5b55af82f26
Autor:
Derek J. C. Tai, Yen C. Liu, Wei L. Hsu, Yun L. Ma, Sin J. Cheng, Shau Y. Liu, Eminy H. Y. Lee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
Post-translational modifications of methyl-CpG-binding protein 2 (MeCP2) are important for its function and dysfunction in Rett syndrome. Here, Tai et al. show a functional interaction between MeCP2 SUMOylation and phosphorylation in rodent behavior
Externí odkaz:
https://doaj.org/article/12ecdd0778e649b788738dc5fc934974
Autor:
Yun L. Ma, Shau Y. Liu, Wei L. Hsu, Sin J. Cheng, Eminy H.Y. Lee, Yen C. Liu, Derek J. C. Tai
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
Nature Communications
Nature Communications
The methyl-CpG-binding protein 2 (MeCP2) gene, MECP2, is an X-linked gene encoding the MeCP2 protein, and mutations of MECP2 cause Rett syndrome (RTT). However, the molecular mechanism of MECP2-mutation-caused RTT is less known. Here we find that MeC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f5233f218890c94c7af8c5d5caf8de
https://doaj.org/article/12ecdd0778e649b788738dc5fc934974
https://doaj.org/article/12ecdd0778e649b788738dc5fc934974
Publikováno v:
Brain Pathology. 21:150-162
Brain-derived neurotrophic factor (BDNF) was shown to produce its neuroprotective effect through extracellular signal-regulated kinase 1/2 (ERK1/2) and phosphatidylinositol-3 kinase (PI3-K) signaling. But whether other pathways also mediate the neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c08ee18afac8db8871e9025c63e1946
https://doi.org/10.1111/j.1750-3639.2010.00431.x
https://doi.org/10.1111/j.1750-3639.2010.00431.x
Publikováno v:
The EMBO Journal. 30:205-220
By using differential display PCR, we have previously identified 98 cDNA fragments from rat dorsal hippocampus, which are expressed differentially between the fast learners and slow learners from water-maze learning task. One cDNA fragment, which sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae0e8477fe9da696b2bf4dce36a7d00d
https://doi.org/10.1038/emboj.2010.290
https://doi.org/10.1038/emboj.2010.290
Publikováno v:
Journal of Neuroscience. 27:6243-6248
Casein kinase II (CK2) is a multifunctional serine/threonine protein kinase that is associated with the development of neuritogenesis and synaptic plasticity. The phosphoinositide 3-kinase (PI-3K)/Akt pathway is implicated in long-term memory formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2982dbd7fa983c33c85f101098063ea8
https://doi.org/10.1523/jneurosci.1531-07.2007
https://doi.org/10.1523/jneurosci.1531-07.2007
Publikováno v:
Learning & Memory. 13:114-118
Previous studies showed that the serum- and glucocorticoid-inducible kinase (sgk) gene plays an important role in long-term memory formation. The present study further examined the role of SGK in long-term potentiation (LTP). The dominant-negative mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c601eb0712b83fb16aec3668da231a8
https://doi.org/10.1101/lm.179206
https://doi.org/10.1101/lm.179206
Publikováno v:
European Journal of Neuroscience. 23:1311-1320
We have previously demonstrated that serum- and glucocorticoid-inducible kinase (SGK) plays a causal role in facilitating memory formation of spatial learning in rats, but the SGK signaling pathway involved in spatial memory formation is not known. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2316c5f761b8f1d2d648baf805e6a6c
https://doi.org/10.1111/j.1460-9568.2006.04650.x
https://doi.org/10.1111/j.1460-9568.2006.04650.x
Publikováno v:
Proceedings of the National Academy of Sciences. 99:3990-3995
By using differential display PCR, we have identified 98 cDNA fragments from the rat dorsal hippocampus that are expressed differentially between the fast learners and slow learners in the water maze learning task. One of these cDNA fragments encodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b96e117a482f6ffb830b335c05b7e5a
https://doi.org/10.1073/pnas.062405399
https://doi.org/10.1073/pnas.062405399
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 36(12)
Laminin is a major structural element of the basal lamina consisting of an α-chain, a β-chain, and a γ-chain arranged in a cross-like structure, with their C-terminal inter-coiled. Laminin is abundantly expressed in the hippocampus of mature brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3891eb63aefbf65af7201d4b7737c26
https://pubmed.ncbi.nlm.nih.gov/21849984
https://pubmed.ncbi.nlm.nih.gov/21849984