Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Yun Kyoung Lee"'
Autor:
In-hee Kwak, Yun Kyoung Lee, Hyeo-il Ma, Sangwon Lee, Mijin Yun, Yun Joong Kim, Hee Sung Hwang, Young Eun Kim
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 1, p 18 (2023)
Background and Purpose: REM sleep behavior disorder (RBD) in Parkinson’s disease (PD) is associated with characteristic clinical subtypes and prognosis. In addition, nigrostriatal pathway, the most vulnerable anatomical area in PD, formed neuronal
Externí odkaz:
https://doaj.org/article/85dcb8566a7d409db596b08ab2832d0a
Autor:
Yun-Kyoung Lee, Wen Du, Yaohui Nie, Bryan Diaz, Nishat Sultana, Takumi Kitamoto, Rudolph L. Leibel, Domenico Accili, Sandro Belvedere
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101618- (2022)
Objectives: Insulin treatment remains the sole effective intervention for Type 1 Diabetes. Here, we investigated the therapeutic potential of converting intestinal epithelial cells to insulin-producing, glucose-responsive β-like cells by targeted in
Externí odkaz:
https://doaj.org/article/5b916d96958240c9a77147b77b3d5577
Autor:
Takumi Kitamoto, Yun-Kyoung Lee, Nishat Sultana, Hitoshi Watanabe, Wendy M. McKimpson, Wen Du, Jason Fan, Bryan Diaz, Hua V. Lin, Rudolph L. Leibel, Sandro Belvedere, Domenico Accili
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101624- (2022)
Objective: Lifelong insulin replacement remains the mainstay of type 1 diabetes treatment. Genetic FoxO1 ablation promotes enteroendocrine cell (EECs) conversion into glucose-responsive β-like cells. Here, we tested whether chemical FoxO1 inhibitors
Externí odkaz:
https://doaj.org/article/df93c47e5c174cc68dabf3af76c69142
Autor:
Yun-Kyoung Lee, Bryan Diaz, Marianne Deroose, Samuel X. Lee, Sandro Belvedere, Domenico Accili, Rudolph L. Leibel, Hua V. Lin
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101187- (2021)
Objective: Forkhead box protein O1 (FOXO1) plays a key role in regulating hepatic glucose production, but investigations of FOXO1 inhibition as a potential therapeutic approach have been hampered by a lack of selective chemical inhibitors. By profili
Externí odkaz:
https://doaj.org/article/638a5b8971d74b309029bffc59f3e20e
Publikováno v:
Social Economy & Policy Studies. 10:205-231
Autor:
Young Eun Kim, Hee Sung Hwang, Yun Joong Kim, Mijin Yun, Sangwon Lee, Hyeo-il Ma, Yun Kyoung Lee, In-hee Kwak
Publikováno v:
Journal of Integrative Neuroscience. 22:18
Autor:
Yu-Seong Choi, Jinyoung Park, Soyeon Park, Pureum Noh, Gilsang Jeong, Yun-Kyoung Lee, Jongmin Yoon, Sunghoon Choi, Seon Deok Jin
Publikováno v:
The Korean Journal of Ornithology. 26:69-74
Autor:
Anne M Whalen, Jian Li, Wenyu Fu, Lorin Weiner, Mario Clemente Estable, Laurel A. Raftery, Yun-Kyoung Lee, Janice L. Brissette, Kristin White
Publikováno v:
EMBO Reports
EMBO Rep
EMBO Rep
A long‐standing problem in biology is how to dissect traits for which no tractable model exists. Here, we screen for genes like the nude locus (Foxn1)—genes central to mammalian hair and thymus development—using animals that never evolved hair,
Autor:
Sabyasachi Dash, Yun-Kyoung Lee, Jenny Xiang, Teresa Sanchez, Hiroki Uchida, Keri Callegari, Akira Ito, Tuo Zhang
Increasing evidence implicates cerebral microvascular dysfunction in the pathophysiology of numerous central nervous system pathologies, including stroke. Understanding the molecular alterations in cerebral microvessels in these conditions will provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a034e743cb81eb970bb0b66c74bb316
The molecular characterization of cerebral microvessels in experimental disease models has been hindered by the lack of a standardized method to reproducibly isolate intact cerebral microvessels, with consistent cellular compositions, and without the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c158f15a51cc046cc1958384adfcb9