Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yun K. Hahn"'
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Opioid use disorder (OUD) is a critical problem that contributes to the spread of HIV and may intrinsically worsen neuroHIV. Despite the advent of combined antiretroviral therapies (cART), about half of persons infected with HIV (PWH) experience cogn
Externí odkaz:
https://doaj.org/article/794d623f615d423caa4d007d496ffa56
Autor:
Sara R. Nass, Yun K. Hahn, Michael Ohene-Nyako, Virginia D. McLane, M. Imad Damaj, Leroy R. Thacker, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Viruses, Vol 15, Iss 3, p 590 (2023)
Opioid use disorder (OUD) and HIV are comorbid epidemics that can increase depression. HIV and the viral protein Tat can directly induce neuronal injury within reward and emotionality brain circuitry, including the prefrontal cortex (PFC). Such damag
Externí odkaz:
https://doaj.org/article/5268e4498a2d4d1f9e58f8b18d1037fa
Publikováno v:
ASN Neuro, Vol 13 (2021)
People infected with HIV (PWH) are highly susceptible to striatal and hippocampal damage. Motor and memory impairments are common among these patients, likely as behavioral manifestations of damage to these brain regions. GABAergic dysfunction from H
Externí odkaz:
https://doaj.org/article/b0db22fe778a4366ae859dcb815f3f00
Autor:
Sara R. Nass, Yun K. Hahn, Virginia D. McLane, Neil B. Varshneya, M. Imad Damaj, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 5, Iss , Pp 100077- (2020)
HIV-1 selectively disrupts neuronal integrity within specific brain regions, reflecting differences in viral tropism and/or the regional differences in the vulnerability of distinct neuronal subpopulations within the CNS. Deficits in prefrontal corte
Externí odkaz:
https://doaj.org/article/36d781f16f68483aa88fb1011fa10433
Autor:
Yun K. Hahn, Jason J. Paris, Aron H. Lichtman, Kurt F. Hauser, Laura J. Sim-Selley, Dana E. Selley, Pamela E. Knapp
Publikováno v:
Neurobiology of Disease, Vol 92, Iss , Pp 124-136 (2016)
Co-exposure to opiates and HIV/HIV proteins results in enhanced CNS morphological and behavioral deficits in HIV+ individuals and in animal models. Opiates with abuse liability, such as heroin and morphine, bind preferentially to and have pharmacolog
Externí odkaz:
https://doaj.org/article/46a94e8e2b4741659b64212514726b3d
Autor:
Viktor Yarotskyy, Arianna R. S. Lark, Sara R. Nass, Yun K. Hahn, Michael G. Marone, A. Rory McQuiston, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Am J Physiol Cell Physiol
Dynamic chloride (Cl−) regulation is critical for synaptic inhibition. In mature neurons, Cl− influx and extrusion are primarily controlled by ligand-gated anion channels (GABAA and glycine receptors) and the potassium chloride cotransporter K+-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdfb8a93234a59dc3a1bf6ea1c5e3ef
https://europepmc.org/articles/PMC8917939/
https://europepmc.org/articles/PMC8917939/
Autor:
Kurt F. Hauser, Pamela E. Knapp, M. Imad Damaj, Virginia D. McLane, Neil B. Varshneya, Sara R. Nass, Yun K. Hahn
Publikováno v:
Brain, behavior, & immunity-health
Brain, Behavior, & Immunity-Health, Vol 5, Iss, Pp 100077-(2020)
Brain, Behavior, & Immunity-Health, Vol 5, Iss, Pp 100077-(2020)
HIV-1 selectively disrupts neuronal integrity within specific brain regions, reflecting differences in viral tropism and/or the regional differences in the vulnerability of distinct neuronal subpopulations within the CNS. Deficits in prefrontal corte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1a767df64c48e0d40b35f811056bac
http://europepmc.org/articles/PMC7571616
http://europepmc.org/articles/PMC7571616
Autor:
Pamela E. Knapp, T. Celeste Napier, Virginia D. McLane, Therese M. Ihrig, Sara R. Nass, Arianna R.S. Lark, Liangru Contois, Yun K. Hahn, Kurt F. Hauser
Publikováno v:
Horm Behav
Many persons infected with HIV-1 (PWH) and opioid-dependent individuals experience deficits in sociability that interfere with daily living. Sociability is regulated by the prefrontal cortico-hippocampal-amygdalar circuit. Within this circuit HIV-1 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215f364969368b65666de3157c205449
https://doi.org/10.1016/j.yhbeh.2021.105008
https://doi.org/10.1016/j.yhbeh.2021.105008
Publikováno v:
ASN NEURO
ASN Neuro, Vol 13 (2021)
ASN Neuro, Vol 13 (2021)
People infected with HIV (PWH) are highly susceptible to striatal and hippocampal damage. Motor and memory impairments are common among these patients, likely as behavioral manifestations of damage to these brain regions. GABAergic dysfunction from H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9bc3fb103a9b8aa66f8317fc342fab2
https://doi.org/10.1177/17590914211022089
https://doi.org/10.1177/17590914211022089
Publikováno v:
Neurosci Lett
Opiate abuse is prevalent among HIV-infected individuals and may exacerbate HIV-associated age-related neurocognitive disorders. However, the extent to which HIV and opiates converge to accelerate pathological traits indicative of brain aging remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884b3df4ef0ab0d5d8139e48c2ad7f15
https://doi.org/10.1016/j.neulet.2020.135502
https://doi.org/10.1016/j.neulet.2020.135502