Zobrazeno 1 - 10
of 4 975
pro vyhledávání: '"Yun Huang"'
Autor:
Jiabao Zhang, Aili Zhang, Jiaxin Liu, Xu Xiao, Yun Huang, Wei Zhou, Shenghui Chen, Ping Yu, Yifeng Xie, Sili Wang, Zhan Chen, Jianbao Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Objective The CHOP combined chemotherapy regimen (cyclophosphamide, doxorubicin, vincristine, and prednisone) is commonly used to treat non-Hodgkin Lymphoma (NHL). While these drugs are effective for cancer treatment, they may have side effe
Externí odkaz:
https://doaj.org/article/7b22af908e5b4315b53d38126db986aa
Autor:
Yanyan Zhang, Yun Huang, Dianping Yu, Mengting Xu, Hongmei Hu, Qing Zhang, Minchen Cai, Xiangxin Geng, Hongwei Zhang, Jianhua Xia, Mengmeng Guo, Dong Lu, Hanchi Xu, Linyang Li, Xing Zhang, Qun Wang, Sanhong Liu, Weidong Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4312-4328 (2024)
Programmed cell death ligand-1 (PD-L1) is a T cell inhibitory immune checkpoint molecule that interacts with programmed cell death-1 (PD-1) to promote immune escape of tumor cells. Compared with antibody therapies, small molecule drugs show better pr
Externí odkaz:
https://doaj.org/article/a7130bd47bb441cfbc68faa19f780568
Autor:
Zitong Huang, Liling Lin, Xing Li, Zuhua Rong, Jianxiong Hu, Jianguo Zhao, Weilin Zeng, Zhihua Zhu, Yihong Li, Yun Huang, Li Zhang, Dexin Gong, Jiaqing Xu, Yan Li, Huibing Lai, Wangjian Zhang, Yuantao Hao, Jianpeng Xiao, Lifeng Lin
Publikováno v:
Archives of Public Health, Vol 82, Iss 1, Pp 1-9 (2024)
Abstract Background From January 2020 to June 2022, strict interventions against COVID-19 were implemented in Guangdong Province, China. However, the evolution of COVID-19 dynamics remained unclear in this period. Objectives This study aims to invest
Externí odkaz:
https://doaj.org/article/f77eafc458b84cfe8a1db5355931f6ec
Autor:
Ling Jiang, Yu Zhao, Fang Liu, Yun Huang, Yujiao Zhang, Baoyi Yuan, Jiaying Cheng, Ping Yan, Jinle Ni, Yongshuai Jiang, Quan Wu, Xuejie Jiang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Approximately 25–30% of patients with acute myeloid leukemia (AML) have FMS-like receptor tyrosine kinase-3 (FLT3) mutations that contribute to disease progression and poor prognosis. Prolonged exposure to FLT3 tyrosine kinase i
Externí odkaz:
https://doaj.org/article/14b61ae9140e425ebfee0407ee01a1be
Autor:
Yu Wang, Wenjun Wei, Heming Guo, Dengmin Wang, Xueli Wei, Chunlan Zhang, Xiaoyan Zhang, Yun Huang
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 8, Pp 1115-1128 (2024)
ABSTRACT Aims/Introduction Type 2 diabetes mellitus is a major metabolic disease that seriously endangers life and health, but women with gestational diabetes mellitus are at increased risk for developing type 2 diabetes mellitus. This study aimed to
Externí odkaz:
https://doaj.org/article/db10415d0a764acca4cf1c7e6eef6201
Autor:
Mengmeng Zhu, Qiaoliang Huang, Heng Li, Yujie Zhao, Heming Guo, Tao Wang, Xiaodan Liu, Yun Huang, Ji Hu, Chen Fang, Jian Huang
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e39934- (2024)
Aims: This study explores the correlation between site-specific methylation levels of the KCNJ11 promoter and type 2 diabetes mellitus (T2DM), analyzing potential molecular mechanisms. Methods: Thirty patients newly diagnosed with T2DM and 30 healthy
Externí odkaz:
https://doaj.org/article/191c9e79832a4ae0b5af1d28eb9c5ae1
Publikováno v:
Environmental Science and Ecotechnology, Vol 22, Iss , Pp 100480- (2024)
Biofilm reactors, known for utilizing biofilm formation for cell immobilization, offer enhanced biomass concentration and operational stability over traditional planktonic systems. However, the dense nature of biofilms poses challenges for substrate
Externí odkaz:
https://doaj.org/article/2bfe9d3d2aaa460ba1a93e6a9da1a52a
Autor:
Haoyu Wang, Mu Xu, Tong Zhang, Jinkun Pan, Chaopu Li, Bei Pan, Linpeng Zhou, Yun Huang, Chenzi Gao, Mengping He, Yao Xue, Xuetao Ji, Xu Zhang, Ning Wang, Hongwen Zhou, Qian Wang, John Zhong Li
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Liver cancer (LC) is among the deadliest cancers worldwide, with existing treatments showing limited efficacy. This study aimed to elucidate the role and underlying mechanisms of pyrroline‐5‐carboxylate reductase 1 (PYCR1) as
Externí odkaz:
https://doaj.org/article/b74992dd2cbd43668e2a947cdf52e33a
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionPyroptosis is an inflammatory form of programmed cell death that plays a significant role in tumorigenesis. Cinobufotalin (CB), a bufadienolide extracted from toad venom, is associated with antitumor effects in various cancers, including
Externí odkaz:
https://doaj.org/article/992d57faf0ba47b5a9c991019746834c
Autor:
Cordelia Dunai, Claire Hetherington, Sarah A. Boardman, Jordan J. Clark, Parul Sharma, Krishanthi Subramaniam, Kukatharmini Tharmaratnam, Edward J. Needham, Robyn Williams, Yun Huang, Greta K. Wood, Ceryce Collie, Andrew Fower, Hannah Fox, Mark A. Ellul, Marie Held, Franklyn N. Egbe, Michael Griffiths, Tom Solomon, Gerome Breen, Anja Kipar, Jonathan Cavanagh, Sarosh R. Irani, Angela Vincent, James P. Stewart, Leonie S. Taams, David K. Menon, Benedict D. Michael
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Neurological complications, including encephalopathy and stroke, occur in a significant proportion of COVID-19 cases but viral protein is seldom detected in the brain parenchyma. To model this situation, we developed a novel low-inoculum K18-hACE2 mo
Externí odkaz:
https://doaj.org/article/b407a024b99e4716aa954f209f08e65d