Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yun Fu Hu"'
Autor:
Jai P. Pandey, Robert N. Schuck, Gideon M. Blumenthal, Laura M. Koontz, E. David Litwack, Eunice Y. Lee, Pamela Gallagher, Reena Philip, Anand Pathak, Hisani N. Horne, Julia A. Beaver, Yun Fu Hu, Donna Roscoe
Publikováno v:
JCO Precis Oncol
PURPOSE: Next-generation sequencing (NGS) oncology panels are becoming integral in hospital and academic settings to guide patient treatment and enrollment in clinical trials. Although NGS technologies have revolutionized decision-making for cancer t
Publikováno v:
Molecular Endocrinology. 24:657-666
When fed with a high-fat safflower oil diet for 3 wk, wild-type mice develop hepatic insulin resistance, whereas mice lacking glycerol-3-phosphate acyltransferase-1 retain insulin sensitivity. We examined early changes in the development of insulin r
Publikováno v:
Expert review of molecular diagnostics. 15(7)
Companion diagnostics are essential for the safe and effective use of the corresponding therapeutic products. The US FDA has approved a number of companion diagnostics used to select cancer patients for treatment with contemporaneously approved novel
Publikováno v:
Current Molecular Medicine. 5:29-38
Traditional biomarkers have played an important role in drug development as well as patient care. A single traditional biomarker or surrogate endpoint is unlikely to either characterize the complete pathophysiology of a complex disease or capture all
Autor:
Quivo Tahin, Xiang Ao, Jose Russo, Carolyn M. Slater, Irma H. Russo, Yun Fu Hu, M. Hasan Lareef
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 80:149-162
The association found between breast cancer development and prolonged exposure to estrogen suggests that this hormone is of etiologic importance in the causation of this disease. In order to prove this postulate, we treated the immortalized human bre
Publikováno v:
Statistics in medicine. 34(14)
A key component of personalized medicine is companion diagnostics that measure biomarkers, for example, protein expression, gene amplification or specific mutations. Most of the recent attention concerning molecular cancer diagnostics has been focuse
Autor:
JOSE RUSSO, YUN FU HU, QUIVO TAHIN, DANA MIHAILA, CAROLYN SLATER, M. HASAN LAREEF, IRMA H. RUSSO
Publikováno v:
APMIS. 109:S95-S111
Autor:
Carolyn M. Slater, Dana Mihaila, Yun Fu Hu, M. Hasan Lareef, Quivo Tahin, Irma H. Russo, Jose Russo
Publikováno v:
APMIS. 109:39-52
Epidemiological and clinical evidences indicate that breast cancer risk is associated with prolonged ovarian function that results in elevated circulating levels of steroid hormones. Principal among these is estrogen, which is associated with two imp
Publikováno v:
Microscopy Research and Technique. 52:204-223
The breast undergoes dramatic changes in size, shape, and function in association with growth, reproduction, and post-menopausal regression. Those changes impact women's lifetime breast cancer risk. An early first full-term pregnancy exerts a protect
Publikováno v:
JNCI Monographs. 2000:17-37
Breast cancer, which is the most common neoplastic disease in females and accounts for up to one third of all new cases of women's cancer in North America, continues to rise in incidence. In addition, the mortality caused by this disease has remained