Zobrazeno 1 - 10
of 1 504
pro vyhledávání: '"Yun Che"'
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Lung squamous cell carcinoma (LUSC) is the second most common lung cancer worldwide, leading to millions of deaths annually. Although immunotherapy has expanded the therapeutic choices for LUSC and achieved considerable efficacy in a subset
Externí odkaz:
https://doaj.org/article/1d4d24951dca4eb8961edd4d14f927e0
Autor:
Chaoqi Zhang, Feng Wang, Nan Sun, Zhen Zhang, Guochao Zhang, Zhihui Zhang, Yuejun Luo, Yun Che, Hong Cheng, Jiagen Li, Jie He
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 415-428 (2022)
Studies on immune checkpoint inhibitors targeting B7-CD28 family pathways in esophageal squamous cell carcinoma (ESCC) have shown promising results. However, a comprehensive understanding of B7-CD28 family members in ESCC is still limited. This study
Externí odkaz:
https://doaj.org/article/b201ff4c45374c36b159e1da1dd632ec
Autor:
Lingling Fang, Yun Che, Chaoqi Zhang, Jianbing Huang, Yuanyuan Lei, Zhiliang Lu, Nan Sun, Jie He
Publikováno v:
Molecular Oncology, Vol 15, Iss 11, Pp 3125-3146 (2021)
Cancer‐associated fibroblasts (CAF) are a heterogeneous cell population within the tumor microenvironment,and play an important role in tumor development. By regulating the heterogeneity of CAF, transforming growth factor β (TGFβ) influences tumo
Externí odkaz:
https://doaj.org/article/b4d49d87482c43cf818717a8308c8541
Autor:
Lingling Fang, Yun Che, Chaoqi Zhang, Jianbing Huang, Yuanyuan Lei, Zhiliang Lu, Nan Sun, Jie He
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Cancer-associated fibroblasts (CAFs) plays an important role in the tumor microenvironment. The heterogeneity of CAFs affects the effect of CAFs on promoting or inhibiting tumors, which can be regulated by other cells in the tumor microenvir
Externí odkaz:
https://doaj.org/article/325a4bd9923a4995a675015869e22ea3
Autor:
Shuangshuang Mao, Yuan Li, Zhiliang Lu, Yun Che, Jianbing Huang, Yuanyuan Lei, Yalong Wang, Chengming Liu, Xinfeng Wang, Sufei Zheng, Nan Sun, Jie He
Publikováno v:
Cancer Medicine, Vol 8, Iss 5, Pp 2429-2441 (2019)
Abstract Alternative splicing (AS) and the regulation of AS by splicing factors play critical roles in cancer. Plant homeodomain (PHD)–finger domain protein PHF5A, a critical splicing factor involved in AS, has been demonstrated to play an oncogeni
Externí odkaz:
https://doaj.org/article/697c203cca1e4252907df9b369ec9643
Autor:
Chaoqi Zhang, Yuejun Luo, Zhen Zhang, Zhihui Zhang, Guochao Zhang, Feng Wang, Yun Che, Lingling Fang, Yi Zhang, Nan Sun, Jie He
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Immunotherapy has achieved success in the treatment of esophageal squamous cell carcinoma (ESCC). However, studies concerning immune phenotypes within the ESCC microenvironment and their relationship with prognostic outcomes are limited. We construct
Externí odkaz:
https://doaj.org/article/8d808855fae343bdb1337798c501a8e6
Autor:
Chaoqi Zhang, Guochao Zhang, Nan Sun, Zhen Zhang, Zhihui Zhang, Yuejun Luo, Yun Che, Qi Xue, Jie He
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102959- (2020)
Background: Tumour Necrosis Factor (TNF) family members play important roles in mounting anti-tumour immune responses, and clinical trials targeting these molecules are ongoing. However, the expression patterns and clinical significance of TNF member
Externí odkaz:
https://doaj.org/article/55ed7bd2906047f7b3d55c1f107463a0
Autor:
Chaoqi Zhang, Zhihui Zhang, Guochao Zhang, Liyan Xue, Haijun Yang, Yuejun Luo, Xiaoli Zheng, Yonglei Zhang, Yufen Yuan, Ruixue Lei, Zhaoyang Yang, Bo Zheng, Zhen Zhang, Le Wang, Yun Che, Sihui Wang, Feng Wang, Lingling Fang, Qingpeng Zeng, Jiagen Li, Shugeng Gao, Qi Xue, Nan Sun, Jie He
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 4, Pp n/a-n/a (2020)
Abstract Background Current strategies are insufficient to predict pathologically complete response (pCR) for esophageal squamous cell carcinomas (ESCCs) before treatment. Here, we aim to develop a novel long noncoding RNA (lncRNA) signature for pCR
Externí odkaz:
https://doaj.org/article/370cb2c660b840cbbfacb2807738bf82
Autor:
Yuanyuan Lei, Nan Sun, Guochao Zhang, Chengming Liu, Zhiliang Lu, Jianbing Huang, Chaoqi Zhang, Ruochuan Zang, Yun Che, Shuangshuang Mao, Lingling Fang, Xinfeng Wang, Sufei Zheng, Jie He
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 3, Pp n/a-n/a (2020)
Abstract Background Many tumor‐derived endothelial cells (TECs) are shed into the blood and turn into circulating TECs (CTECs). Rare circulating non‐hematologic aneuploid cells contain CTCs and CTECs, which are biologically and functionally diffe
Externí odkaz:
https://doaj.org/article/33542e7952b94e4ba829ab4cfc0293a2
Autor:
Chaoqi Zhang, Zhihui Zhang, Nan Sun, Zhen Zhang, Guochao Zhang, Feng Wang, Yuejun Luo, Yun Che, Jie He
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Background Costimulatory molecules play significant roles in mounting anti-tumor immune responses, and antibodies targeting these molecules are recognized as promising adjunctive cancer immunotherapies. Here, we aim to conduct a first full-scale expl
Externí odkaz:
https://doaj.org/article/c51b4ca67137429d8a7cb93fae29c145