Zobrazeno 1 - 10
of 438
pro vyhledávání: '"Yun Bo Shi"'
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background The adult intestinal epithelium is a complex, self-renewing tissue composed of specialized cell types with diverse functions. Intestinal stem cells (ISCs) located at the bottom of crypts, where they divide to either self-renew, or
Externí odkaz:
https://doaj.org/article/448371cac9694777a9530ddc50b06c00
Autor:
Yang Liu, Feifei Song, Xianhuang Zeng, Siqi Yang, Zixu Zhai, Ze Wang, Wajeeha Naz, Tanzeel Yousaf, Junwei Sun, Yangjun Zhang, Ying Zhou, Mingxiong Guo, Yun-Bo Shi, Geng Tian, Guihong Sun
Publikováno v:
Genes and Diseases, Vol 12, Iss 2, Pp 101316- (2025)
Externí odkaz:
https://doaj.org/article/53c45aa963b6429d80b3f5986a4fe00e
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract Targeted genome editing is a powerful tool for studying gene function in almost every aspect of biological and pathological processes. The most widely used genome editing approach is to introduce engineered endonucleases or CRISPR/Cas system
Externí odkaz:
https://doaj.org/article/2096fe1a402b4222b3ef877cdbd95653
Autor:
Shouhong Wang, Yuki Shibata, Liezhen Fu, Yuta Tanizaki, Nga Luu, Lingyu Bao, Zhaoyi Peng, Yun-Bo Shi
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Animal regeneration is the natural process of replacing or restoring damaged or missing cells, tissues, organs, and even entire body to full function. Studies in mammals have revealed that many organs lose regenerative ability soo
Externí odkaz:
https://doaj.org/article/86af79ac63654189b0de74c893c9ea27
Publikováno v:
Cells, Vol 13, Iss 3, p 247 (2024)
Targeted genome editing is a powerful tool in reverse genetic studies of gene function in many aspects of biological and pathological processes. The CRISPR/Cas system or engineered endonucleases such as ZFNs and TALENs are the most widely used genome
Externí odkaz:
https://doaj.org/article/9c6523c536a748bebcea3ace14beccdd
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Amphibian metamorphosis resembles mammalian postembryonic development, a period around birth when many organs mature into their adult forms and when plasma thyroid hormone (T3) concentration peaks. T3 plays a causative role for amphibian metamorphosi
Externí odkaz:
https://doaj.org/article/d9cb30b5f444404b84bc02669f1ae1e5
Autor:
Gyujin Park, Kazuya Fukasawa, Tetsuhiro Horie, Yusuke Masuo, Yuka Inaba, Takanori Tatsuno, Takanori Yamada, Kazuya Tokumura, Sayuki Iwahashi, Takashi Iezaki, Katsuyuki Kaneda, Yukio Kato, Yasuhito Ishigaki, Michihiro Mieda, Tomohiro Tanaka, Kazuma Ogawa, Hiroki Ochi, Shingo Sato, Yun-Bo Shi, Hiroshi Inoue, Hojoon Lee, Eiichi Hinoi
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Hypothalamic neurons regulate body homeostasis by sensing and integrating changes in the levels of key hormones and primary nutrients (amino acids, glucose, and lipids). However, the molecular mechanisms that enable hypothalamic neurons to detect pri
Externí odkaz:
https://doaj.org/article/69274c6ccd734fd68d05813f708b0c90
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106301- (2023)
Summary: Thyroid hormone (T3) regulates vertebrate organ development, growth, and metabolism through the T3 receptor (TR). Due to maternal influence in mammals, it has been difficult to study if and how T3 regulates liver development. Liver remodelin
Externí odkaz:
https://doaj.org/article/65333bd9ca364ccda83c18c29600f0bd
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Tanizaki et al use ChIP-Seq to identify over 3000 Thyroid hormone (T3) receptor (TR)-bound genes in the intestine of premetamorphic wild type Xenopus tropicalis tadpoles and in TRα-knockouts. They show that treatment of tadpoles with cell cycle inhi
Externí odkaz:
https://doaj.org/article/cb0feff07804433abbe48613e9225b4b
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 11, Pp 1001-1012 (2021)
Introduction: Tadpole tail develops from the tailbud, an apparently homogenous mass of cells at the posterior of the embryo. While much progress has been made in understanding the origin and the induction of the tailbud, the subsequent outgrowth and
Externí odkaz:
https://doaj.org/article/62f60902d0904b24872c8a328088a1c5