Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yun‐Song Yang"'
Autor:
Fan Yang, Rui Sun, Zeng Hou, Fang‐Lin Zhang, Yi Xiao, Yun‐Song Yang, Shao‐Ying Yang, Yi‐Fan Xie, Ying‐Ying Liu, Cheng Luo, Guang‐Yu Liu, Zhi‐Min Shao, Da‐Qiang Li
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Abstract Aims MORC family CW‐type zinc finger 2 (MORC2), a GHKL‐type ATPase, is aberrantly upregulated in multiple types of human tumors with profound effects on cancer aggressiveness, therapeutic resistance, and clinical outcome, thus making it
Externí odkaz:
https://doaj.org/article/74c9297b325c4c5c89950cc75fdb96a8
Autor:
Guan-Tian Lang, Yi-Zhou Jiang, Jin-Xiu Shi, Fan Yang, Xiao-Guang Li, Yu-Chen Pei, Chen-Hui Zhang, Ding Ma, Yi Xiao, Peng-Chen Hu, Hai Wang, Yun-Song Yang, Lin-Wei Guo, Xun-Xi Lu, Meng-Zhu Xue, Peng Wang, A-Yong Cao, Hong Ling, Zhong-Hua Wang, Ke-Da Yu, Gen-Hong Di, Da-Qiang Li, Yun-Jin Wang, Ying Yu, Le-Ming Shi, Xin Hu, Wei Huang, Zhi-Ming Shao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Chinese breast cancer patients have not been well represented in clinical sequencing studies. Here the authors analyse the mutational landscape of 1,134 Chinese breast cancer patients, finding actionable targets and a higher prevalence of p53 and Hip
Externí odkaz:
https://doaj.org/article/61dd0a122435489e99726b2dc7d128dc
Autor:
Lin‐Wei Guo, Xiao‐Guang Li, Yun‐Song Yang, Xun‐Xi Lu, Xiang‐Chen Han, Guan‐Tian Lang, Li Chen, Zhi‐Ming Shao, Xin Hu
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Background Few studies have discussed the contradictory roles of mutated‐PI3Kα in HER2‐positive (HER2+) breast cancer. Thus, we characterised the adaptive roles of PI3Kα mutations among HER2+ tumour progression. Methods We conducted pr
Externí odkaz:
https://doaj.org/article/95e5f690bc48412b8e7f6cd96e0d6269
Autor:
Yun-Song Yang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Purpose Regulatory T cells (Tregs) heavily infiltrate triple-negative breast cancer (TNBC), and their accumulation is affected by the metabolic reprogramming in cancer cells. In the present study, we sought to identify cancer cell-intrinsic metabolic
Externí odkaz:
https://doaj.org/article/68a3d6b36fa14195aaeaa0f6f6feeed4
Publikováno v:
Cancer Research. 83:1711-1724
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with unfavorable outcomes. Developing therapeutic targets for TNBC remains a challenge. Here, we identified that acetyl-CoA acyltransferase 1 (ACAA1) is highly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a1251aad4b62f2286abec55b8abff48
https://doi.org/10.1158/0008-5472.can-22-2143
https://doi.org/10.1158/0008-5472.can-22-2143
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with unfavorable outcomes. Developing therapeutic targets for TNBC remains a challenge. Here, we identified that acetyl-CoA acyltransferase 1 (ACAA1) is highly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e583b46624e200ce14b61165d68d4d
https://doi.org/10.1158/0008-5472.c.6626689
https://doi.org/10.1158/0008-5472.c.6626689
Supplementary methods, figures, figure legends, and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf8ad7a17f06416d75ae5bae3dcd1eb
https://doi.org/10.1158/0008-5472.22732543.v1
https://doi.org/10.1158/0008-5472.22732543.v1
Autor:
Xiao-En Xu, Zhi-Ming Shao, Shuang Hao, Cheng-Lin Liu, Yi-Xing Ren, Yun-Song Yang, Xi Jin, Yi-Zhou Jiang
Publikováno v:
Breast Cancer Research and Treatment. 193:319-330
Purpose: Triple-negative breast cancer (TNBC) is a highly heterogeneous disease. Patients with early-stage TNBCs have distinct likelihood of distant recurrence. Current therapeutic guidance is still limited.Methods: We extracted transcriptome data fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c264e8ab61fc5be7a9e9923a1b784aac
https://doi.org/10.1007/s10549-022-06537-z
https://doi.org/10.1007/s10549-022-06537-z
Introduction: Normalization cancer immunotherapy is a new strategy to treat breast cancer. Sialic acid binding Ig-like lectin 15 (Siglec-15) is a new potential target for normalization cancer immunotherapy. In this study, we evaluated the role of Sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fea5dc063ff781a0d84b3166e0bca27
https://doi.org/10.21203/rs.3.rs-1018792/v2
https://doi.org/10.21203/rs.3.rs-1018792/v2
Autor:
Yun-Song Yang, Xi Jin, Qin Li, Yi-Yu Chen, Fenfang Chen, Hena Zhang, Ying Su, Yi Xiao, Gen-Hong Di, Yi-Zhou Jiang, Shenglin Huang, Zhi-Ming Shao
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The transcription variation, leading to various forms of transcripts and protein diversity, remains largely unexplored in triple-negative breast cancers (TNBCs). Here, we presented a comprehensive analysis of RNA splicing in breast cancer to illustra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aaeb98da13c5a7af91f489ee7cdff10
https://doi.org/10.1073/pnas.2207201119
https://doi.org/10.1073/pnas.2207201119