Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Yun‐Sil Lee"'
Autor:
Joonho Suh, Yun-Sil Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 66-85 (2024)
Abstract Mitochondria have been primarily considered intracellular organelles that are responsible for generating energy for cell survival. However, accumulating evidence suggests that mitochondria are secreted into the extracellular space under phys
Externí odkaz:
https://doaj.org/article/3e32a485f1de426f8e489af03598d9c3
Autor:
Seulgi Jeon, Hee Jin, Jin-Mo Kim, Youmin Hur, Eun Joo Song, Yoon-Jin Lee, Younghwa Na, Jaeho Cho, Yun-Sil Lee
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-15 (2023)
Abstract Background Heat shock protein 27 (HSP27) is overexpressed during pulmonary fibrosis (PF) and exacerbates PF; however, the upregulation of HSP27 during PF and the therapeutic strategy of HSP27 inhibition is not well elucidated. Methods We hav
Externí odkaz:
https://doaj.org/article/d0a375e845924f3cbfe10b963f6260a5
Autor:
Scisung Chung, Mi-Sun Kang, Dauren S. Alimbetov, Gil-Im Mun, Na-Oh Yunn, Yunjin Kim, Byung-Gyu Kim, Minwoo Wie, Eun A. Lee, Jae Sun Ra, Jung-Min Oh, Donghyun Lee, Keondo Lee, Jihan Kim, Seung Hyun Han, Kyong-Tai Kim, Wan Kyun Chung, Ki Hyun Nam, Jaehyun Park, ByungHoon Lee, Sunghoon Kim, Weixing Zhao, Sung Ho Ryu, Yun-Sil Lee, Kyungjae Myung, Yunje Cho
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Aminoacyl-tRNA synthetases possess unique domains. In this study the structure of the vertebrate IARS1 and EARS1 complex reveals that vertebrate IARS1 protects the DNA repair factor BRCA1 from proteolytic degradation via its UBX-fold domain.
Externí odkaz:
https://doaj.org/article/3a702a1ed24a45f995d55ea263c1b376
Autor:
Young Jo Yoo, Seulgi Jeon, Hee Jin, Hee Yeon Won, Mi Gyeong Jeong, Yeseul Cho, Eun Sook Hwang, Younghwa Na, Jaeho Cho, Yun-Sil Lee
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Pulmonary fibrosis (PF) is a progressive lung disease characterized by fibroblast accumulation and collagen deposition, resulting in lung scarring and impaired gas exchange. Current treatments for idiopathic pulmonary fibrosis (IPF) have
Externí odkaz:
https://doaj.org/article/d204f7a99021418ca804732268592569
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114090- (2023)
Mutations in breast cancer-associated 1 (BRCA1) increase the lifetime risk of developing breast cancer by up to 51% over the risk of the general population. Many aspects of this multifunctional protein have been revealed, including its essential role
Externí odkaz:
https://doaj.org/article/497092d4a15d4d5bbbb873adb33661d3
Autor:
Kyeonghee Yoon, Sojung Choi, Hyung-Do Choi, Nam Kim, Sang Bong Jeon, Kyung-Min Lim, Hae-June Lee, Yun-Sil Lee
Publikováno v:
Journal of Electromagnetic Engineering and Science, Vol 20, Iss 4, Pp 307-319 (2020)
The growing concerns regarding the adverse biological effects of radiofrequency electromagnetic fields (RF-EMFs), which are generated by common electronic devices, on the human brain led us to investigate their impact on Alzheimer’s disease (AD). W
Externí odkaz:
https://doaj.org/article/7515ee03d2e44c49a7f053a8ed59d75e
Autor:
Joonho Suh, Yun-Sil Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 10, Pp 1673-1693 (2020)
Growth factors: untangling twin proteins A growth factor protein called GDF11 has potential for rejuvenation of heart, brain, and muscle tissues, but first its relationship with a twin growth factor (MSTN) must be unraveled. Although GDF11 and MSTN a
Externí odkaz:
https://doaj.org/article/b576f82da4d04d7999c6d61e8c98708b
Autor:
YoungJo Yoo, Eun Choi, Yejin Kim, Yunyoung Cha, Eunhye Um, Younghwa Kim, Yunji Kim, Yun-Sil Lee
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112245- (2022)
Cathepsin S (CTSS), a lysosomal protease, belongs to a family of cysteine cathepsin proteases that promote degradation of damaged proteins in the endolysosomal pathway. Aberrant CTSS expression and regulation are associated with the pathogenesis of s
Externí odkaz:
https://doaj.org/article/b449d7c5e2074c2aa98e91e2e9c3c139
Autor:
Areum Oh, Seulgi Jeon, Mi Gyeong Jeong, Hyo Kyeong Kim, Jio Kang, Yun-Sil Lee, Eun Sook Hwang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112225- (2021)
Heat shock protein beta-1 (HSPB1) is a multifaceted protein that controls cellular stress, modulates cell differentiation and development, and inhibits apoptosis of cancer cells. Increased HSPB1 expression is highly associated with poor outcomes in l
Externí odkaz:
https://doaj.org/article/5fc23238ee6641589cafb81ad11214d2
Publikováno v:
Brain and Behavior, Vol 10, Iss 11, Pp n/a-n/a (2020)
Abstract Introduction Due to public concerns about deleterious biological consequences of radiofrequency electromagnetic fields (RF‐EMF), the potential effects of RF‐EMF on the central nervous system have received wide consideration. Methods Here
Externí odkaz:
https://doaj.org/article/15fdf9b3709645df84373dbcb6d5b03a