Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yumin Chun"'
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 10, Pp n/a-n/a (2023)
Abstract Small‐interfering RNA (siRNA) therapy is considered a powerful therapeutic strategy for treating cardiac hypertrophy, an important risk factor for subsequent cardiac morbidity and mortality. However, the lack of safe and efficient in vivo
Externí odkaz:
https://doaj.org/article/2909577102da499dab43f699f339d248
Generation of two PITX2 knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system
Autor:
Dasom Mun, Ji-Young Kang, Yumin Chun, Da-Seul Park, Hyoeun Kim, Nuri Yun, Seung-Hyun Lee, Boyoung Joung
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102940- (2022)
PITX2 is a homeobox gene located in the human 4q25 locus and is commonly associated with atrial fibrillation (AF). Here, we generated two PITX2 knock-out human induced pluripotent stem cell (iPSC) lines using CRISPR/Cas9 genome editing. The edited iP
Externí odkaz:
https://doaj.org/article/728513e601b34ec4b017545106bd69c1
Generation of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system
Autor:
Ji-Young Kang, Dasom Mun, Yumin Chun, Da-Seul Park, Hyoeun Kim, Nuri Yun, Seung-Hyun Lee, Boyoung Joung
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102901- (2022)
TTN mutations are the common genetic cause for various types of cardiomyopathies (e.g., dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy) and skeletal myopathies. Her
Externí odkaz:
https://doaj.org/article/e8b63f964ebf401b8c6c3f49883d1327
Publikováno v:
Stem Cell Research, Vol 63, Iss , Pp 102878- (2022)
E192K missense mutation of TPM1 has been found in different types of cardiomyopathies (e.g., hypertrophic cardiomyopathy, dilated cardiomyopathy, and left ventricular non-compaction), leading to systolic dysfunction, diastolic dysfunction, and/or tac
Externí odkaz:
https://doaj.org/article/1a1f28a69b3b4ac086927170d25560ce
Autor:
Hyunsung Kim, Yeseul Kim, Yumin Chung, Rehman Abdul, Jongmin Sim, Hyein Ahn, Su-Jin Shin, Seung Sam Paik, Han Joon Kim, Kiseok Jang, Dongho Choi
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background SSBP2, single-stranded DNA binding protein 2, is a subunit of the ssDNA-binding complex that is involved in the maintenance of genome stability. The majority of previous studies have suggested a tumor-suppressive role of SSBP2, wh
Externí odkaz:
https://doaj.org/article/c2d20dd03b1a41a7b1fbaecbe5e3f535
Autor:
Yumin Chung, Young Chan Wi, Yeseul Kim, Seong Sik Bang, Jung-Ho Yang, Kiseok Jang, Kyueng-Whan Min, Seung Sam Paik
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 52, Iss 1, Pp 37-44 (2018)
Background Smad4 and PTEN are prognostic indicators for various tumor types. Smad4 regulates tumor suppression, whereas PTEN inhibits cell proliferation. We analyzed and compared the performance of Smad4 and PTEN for predicting the prognosis of patie
Externí odkaz:
https://doaj.org/article/4ed66f4774c4453d99001289034bbc74
Publikováno v:
Diagnostics, Vol 10, Iss 12, p 1097 (2020)
Single-stranded DNA binding protein 2 (SSBP2) is involved in DNA damage response and may induce growth arrest in cancer cells, having a potent tumor suppressor role. SSBP2 is ubiquitously expressed and the loss of its expression has been reported in
Externí odkaz:
https://doaj.org/article/94771258bbc246c6b38d23daf3258991
Autor:
Kijong Yi, Hyunsung Kim, Yumin Chung, Hyein Ahn, Jongmin Sim, Young Chan Wi, Ju Yeon Pyo, Young-Soo Song, Seung Sam Paik, Young-Ha Oh
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 50, Iss 5, Pp 327-336 (2016)
Background Developing predictive markers for hepatocellular carcinoma (HCC) is important, because many patients experience recurrence and metastasis. Epithelial to mesenchymal transition (EMT) is a developmental process that plays an important role d
Externí odkaz:
https://doaj.org/article/0127a28f8342424e9fb6036739ec90e6
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 50, Iss 5, Pp 397-400 (2016)
Externí odkaz:
https://doaj.org/article/c12f62efeab045689155ab1ea112b7a6
Autor:
Hyunsung Kim, Abdul Rehman, Yumin Chung, Kijong Yi, Young Chan Wi, Yeseul Kim, Kiseok Jang, Se Min Jang, Seung Sam Paik
Publikováno v:
Gastroenterology Research and Practice, Vol 2016 (2016)
Background. This study investigated the clinicopathologic significance of extranodal tumor extension in colorectal adenocarcinoma with lymph node metastasis. Method. Included were 419 patients who underwent curative resection for primary colorectal a
Externí odkaz:
https://doaj.org/article/a759b312cd5440c586e188194aa67649